Filtered By:
Condition: Hypertension
Drug: Verapamil
This page shows you your search results in order of date.
Order by Relevance | Date
Total 1 results found since Jan 2013.
Dihydropyridine Ca2+ Channel Blockers Increase Cytosolic Ca2+ by Activating Ca2+-sensing Receptors in Pulmonary Arterial Smooth Muscle Cells.
Conclusions: The dihydropyridine derivatives increase [Ca(2+)](cyt) by potentiating the activity of CaSR in PASMC independently of their blocking (or activating) effect on Ca(2+) channels; therefore, it is possible that use the dihydropyridine Ca(2+) channel blockers (e.g., nifedipine) to treat IPAH patients with upregulated CaSR in PASMC may exacerbate pulmonary hypertension.
PMID: 23300272 [PubMed - as supplied by publisher]
Source: Circulation Research - January 8, 2013 Category: Cardiology Authors: Yamamura A, Yamamura H, Guo Q, Zimnicka AM, Wang J, Ko EA, Smith KA, Pohl NM, Song S, Zeifman A, Makino A, Yuan JX Tags: Circ Res Source Type: research
