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Specialty: Genetics & Stem Cells
Drug: Losartan
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Total 1 results found since Jan 2013.
Calcitriol ameliorates renal injury with high-salt diet-induced hypertension by upregulating GLIS2 expression and AMPK/mTOR-regulated autophagy
Gene. 2022 Jan 31:146239. doi: 10.1016/j.gene.2022.146239. Online ahead of print.ABSTRACTThe goal of the present study was to investigate the protective effect of calcitriol on high-salt diet-induced hypertension. The hypertension rat model was established by a long-term high-salt diet (8% NaCl). Rats were treated with calcitriol, losartan, or their combination. Histological staining was used to confirm renal pathology. Global transcriptome analysis of renal tissues was performed, and the mechanism of the therapeutic effect of calcitriol was analysed by functional annotation and pathway analysis of the differentially expre...
Source: Gene - February 3, 2022 Category: Genetics & Stem Cells Authors: Ruifeng Ding Yufeng Jiang Yi Yang Yong Shi Yang Ji Timing Zhen Zhiliang Fu Xunxia Bao Jia Tan Shuyong Zhang Jiahui Li Kaichen Xing Xinli Zhou Sibo Zhu Source Type: research
