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Condition: Vitiligo
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Total 18 results found since Jan 2013.
miR-196a-2 rs11614913 polymorphism is associated with vitiligo by affecting heterodimeric molecular complexes of Tyr and Tyrp1
In conclusion, our findings suggest that miR-196a-2 polymorphisms can regulate the Tyr levels, which influences the susceptibility of vitiligo.
Source: Archives of Dermatological Research - October 1, 2015 Category: Dermatology Source Type: research
Protease-activated receptor-2 activates NQO-1 via Nrf2 stabilization in keratinocytes
Conclusion: Collectively, PAR-2 activation enhanced nuclear Nrf2 translocation, and PAR-2-mediated Nrf2 activation was attributable to existing Nrf2 stabilization rather than de novo production. Our findings suggest that in addition to induction of inflammation, PAR-2 can play a chemopreventative role via Nrf2 stabilization in keratinocytes.
Source: Journal of Dermatological Science - December 9, 2013 Category: Dermatology Authors: Ji Young Kim, Do Young Kim, Hyojung Son, Yoon Jee Kim, Sang Ho Oh Tags: Regular Articles Source Type: research
