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Condition: Vitiligo
Cancer: Neuroblastoma
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Psoralidin protects against cerebral hypoxia/reoxygenation injury: Role of GAS6/Axl signaling
Phytother Res. 2022 May 18. doi: 10.1002/ptr.7481. Online ahead of print.ABSTRACTPsoralidin (PSO) is a natural phenolic coumarin extracted from the seeds of Psoralea corylifolia L. Growing preclinical evidence indicates that PSO has anti-inflammatory, anti-vitiligo, anti-bacterial, and anti-viral effects. Growth arrest-specific gene 6 (GAS6) and its receptor, Axl, modulate cellular oxidative stress, apoptosis, survival, proliferation, migration, and mitogenesis. Notably, the neuroprotective role of the GAS6/Axl axis has been identified in previous studies. We hypothesize that PSO ameliorates cerebral hypoxia/reoxygenation ...
Source: Cell Research - May 18, 2022 Category: Cytology Authors: Wangrui Lei Songdi Wu Aizhen Zhao Zhen Wu Baoping Ding Wenwen Yang Chenxi Lu Xue Wu Xiyang Li Shaofei Zhang Ye Tian Yang Yang Source Type: research
