Filtered By:
Condition: Ganglions
Drug: Carisoprodol
This page shows you your search results in order of date.
Order by Relevance | Date
Total 1 results found since Jan 2013.
Deimination restores inner retinal visual function in murine demyelinating disease
Progressive loss of visual function frequently accompanies demyelinating diseases such as multiple sclerosis (MS) and is hypothesized to be the result of damage to the axons and soma of neurons. Here, we show that dendritic impairment is also involved in these diseases. Deimination, a posttranslational modification, was reduced in the retinal ganglion cell layer of MS patients and in a transgenic mouse model of MS (ND4 mice). Reduced deimination accompanied a decrease in inner retinal function in ND4 mice, indicating loss of vision. Local restoration of deimination dramatically improved retinal function and elongation of n...
Source: Journal of Clinical Investigation - January 3, 2013 Category: Biomedical Science Authors: Mabel Enriquez-Algeciras, Di Ding, Fabrizio G. Mastronardi, Robert E. Marc, Vittorio Porciatti, Sanjoy K. Bhattacharya Source Type: research
