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Condition: Endometriosis
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Total 104 results found since Jan 2013.
Lowered expression of CCN5 in endometriotic tissues promotes proliferation, migration and invasion of endometrial stromal cells
CONCLUSION: CCN5 can regulate the proliferation, migration and invasion of HESCs and thus plays an important role in EMT of HESCs, suggesting the potential of CCN5 as a therapeutic target for endometriosis.PMID:35249874 | PMC:PMC8901405 | DOI:10.12122/j.issn.1673-4254.2022.01.10
Source: Journal of Southern Medical University - March 7, 2022 Category: Universities & Medical Training Authors: H Cai M Liu M Lin H Li L Shen S Quan Source Type: research
Down-Regulation of Casein Kinase 1 α Contributes to Endometriosis through Phosphatase and Tensin Homolog/Autophagy-Related 7-Mediated Autophagy
Am J Pathol. 2021 Dec;191(12):2195-2202. doi: 10.1016/j.ajpath.2021.08.015.ABSTRACTThe present study aimed to explore the roles of casein kinase 1α (CK1α) in endometriosis and its underlying mechanisms. Endometrial specimen were collected from the patients and healthy volunteers. The expression patterns of CK1α, phosphatase and tensin homolog (PTEN), and autophagy-related proteins were determined using immunohistochemistry staining, Western blot analysis, and quantitative RT-PCR. Besides, the CK1α-overexpressing cells and PTEN knockdown cells were constructed in the endometrial stromal cells isolated from endometriosis...
Source: The American Journal of Pathology - November 23, 2021 Category: Pathology Authors: Aixiu Zhou Qiongyi Cai Yiting Hong Yuchun Lv Source Type: research
