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Source: The International Journal of Biochemistry and Cell Biology
Cancer: Esophagus Cancer
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Total 6 results found since Jan 2013.
AKT serine/threonine kinase 2-mediated phosphorylation of fascin threonine 403 regulates esophageal cancer progression
Int J Biochem Cell Biol. 2022 Feb 24;145:106188. doi: 10.1016/j.biocel.2022.106188. Online ahead of print.ABSTRACTFascin is the main actin-bundling protein in filopodia and is highly expressed in metastatic tumor cells. The overexpression of Fascin has been associated with poor clinical prognosis and metastatic progression. Post-translational modifications of Fascin, such as phosphorylation, can affect the proliferation and invasion of tumor cells by regulating the actin-bundling activity of Fascin. However, the phosphorylation sites of Fascin and their corresponding kinases require further exploration. In the current stud...
Source: The International Journal of Biochemistry and Cell Biology - February 27, 2022 Category: Biochemistry Authors: Zhi-Da Zhang Bing Wen Da-Jia Li Dan-Xia Deng Xiao-Dong Wu Yin-Wei Cheng Lian-Di Liao Lin Long Geng Dong Li-Yan Xu En-Min Li Source Type: research
AKT Serine/Threonine Kinase 2-mediated phosphorylation of Fascin Threonine 403 regulates esophageal cancer progression
Int J Biochem Cell Biol. 2022 Feb 24:106188. doi: 10.1016/j.biocel.2022.106188. Online ahead of print.ABSTRACTFascin is the main actin-bundling protein in filopodia and is highly expressed in metastatic tumor cells. The overexpression of Fascin has been associated with poor clinical prognosis and metastatic progression. Post-translational modifications of Fascin, such as phosphorylation, can affect the proliferation and invasion of tumor cells by regulating the actin-bundling activity of Fascin. However, the phosphorylation sites of Fascin and their corresponding kinases require further exploration. In the current study, w...
Source: The International Journal of Biochemistry and Cell Biology - February 27, 2022 Category: Biochemistry Authors: Zhi-Da Zhang Bing Wen Da-Jia Li Dan-Xia Deng Xiao-Dong Wu Yin-Wei Cheng Lian-Di Liao Lin Long Geng Dong Li-Yan Xu En-Min Li Source Type: research
AKT serine/threonine kinase 2-mediated phosphorylation of fascin threonine 403 regulates esophageal cancer progression
Int J Biochem Cell Biol. 2022 Feb 24;145:106188. doi: 10.1016/j.biocel.2022.106188. Online ahead of print.ABSTRACTFascin is the main actin-bundling protein in filopodia and is highly expressed in metastatic tumor cells. The overexpression of Fascin has been associated with poor clinical prognosis and metastatic progression. Post-translational modifications of Fascin, such as phosphorylation, can affect the proliferation and invasion of tumor cells by regulating the actin-bundling activity of Fascin. However, the phosphorylation sites of Fascin and their corresponding kinases require further exploration. In the current stud...
Source: The International Journal of Biochemistry and Cell Biology - February 27, 2022 Category: Biochemistry Authors: Zhi-Da Zhang Bing Wen Da-Jia Li Dan-Xia Deng Xiao-Dong Wu Yin-Wei Cheng Lian-Di Liao Lin Long Geng Dong Li-Yan Xu En-Min Li Source Type: research
AKT Serine/Threonine Kinase 2-mediated phosphorylation of Fascin Threonine 403 regulates esophageal cancer progression
Int J Biochem Cell Biol. 2022 Feb 24:106188. doi: 10.1016/j.biocel.2022.106188. Online ahead of print.ABSTRACTFascin is the main actin-bundling protein in filopodia and is highly expressed in metastatic tumor cells. The overexpression of Fascin has been associated with poor clinical prognosis and metastatic progression. Post-translational modifications of Fascin, such as phosphorylation, can affect the proliferation and invasion of tumor cells by regulating the actin-bundling activity of Fascin. However, the phosphorylation sites of Fascin and their corresponding kinases require further exploration. In the current study, w...
Source: The International Journal of Biochemistry and Cell Biology - February 27, 2022 Category: Biochemistry Authors: Zhi-Da Zhang Bing Wen Da-Jia Li Dan-Xia Deng Xiao-Dong Wu Yin-Wei Cheng Lian-Di Liao Lin Long Geng Dong Li-Yan Xu En-Min Li Source Type: research
AKT serine/threonine kinase 2-mediated phosphorylation of fascin threonine 403 regulates esophageal cancer progression
Int J Biochem Cell Biol. 2022 Feb 24;145:106188. doi: 10.1016/j.biocel.2022.106188. Online ahead of print.ABSTRACTFascin is the main actin-bundling protein in filopodia and is highly expressed in metastatic tumor cells. The overexpression of Fascin has been associated with poor clinical prognosis and metastatic progression. Post-translational modifications of Fascin, such as phosphorylation, can affect the proliferation and invasion of tumor cells by regulating the actin-bundling activity of Fascin. However, the phosphorylation sites of Fascin and their corresponding kinases require further exploration. In the current stud...
Source: The International Journal of Biochemistry and Cell Biology - February 27, 2022 Category: Biochemistry Authors: Zhi-Da Zhang Bing Wen Da-Jia Li Dan-Xia Deng Xiao-Dong Wu Yin-Wei Cheng Lian-Di Liao Lin Long Geng Dong Li-Yan Xu En-Min Li Source Type: research
