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Role of long noncoding RNA SNHG3 in regulating proliferation, migration and invasion of cervical cancer SiHa cells
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Jun 20;41(6):931-936. doi: 10.12122/j.issn.1673-4254.2021.06.17.ABSTRACTOBJECTIVE: To investigate the regulatory role of the long non-coding RNA (lncRNA) small nucleolar host gene 3 (SNHG3) in proliferation, migration and invasion of human cervical cancer cell line SiHa.OBJECTIVE: Array data were retrieved from GEO database to analyze the expression levels of SNHG3 in cervical cancer and adjacent normal tissues. SiHa cells were transfected with a small interfering RNA (siRNA) targeting SNHG3, and the changes in the transcriptional levels of lncRNA SNHG3 and the epithelial-mesenchymal tra...
Source: Journal of Southern Medical University - July 9, 2021 Category: Universities & Medical Training Authors: Z Sun J Hu K Hu M Tang S Sun Y Fang H Yu Y Zhang Source Type: research

Knocking down fascin inhibits cervical cancer cell proliferation and tumorigenesis in nude mice.
CONCLUSIONS: Knocking down fascin can inhibit the growth and tumorigenicity of cervical cancer cells in nude mice. PMID: 30613006 [PubMed - in process]
Source: Journal of Southern Medical University - December 30, 2018 Category: Universities & Medical Training Authors: Li X, Li S, Wang X, Zhao S, Liu H Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

Effect of RbAp48 knockdown on migration and invasion of human cervical cancer cell line MS751 in vitro.
CONCLUSION: Knockdown of RbAp48 can significantly inhibit epithelial-mesenchymal transition and suppress the migration and invasion of cervical cancer cell line MS751, the mechanism of which may involve the down-regulation of Snail and Twist expressions. PMID: 26607076 [PubMed - as supplied by publisher]
Source: Journal of Southern Medical University - November 20, 2015 Category: Universities & Medical Training Authors: Zhong JJ, Yang XR, Mai MQ, Wang DD, Lv L, Rao JJ Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research

Cisplatin inhibits proliferation of cervical carcinoma cell line by up-regulating Stat1 expression.
CONCLUSION: The expression of Stat1 is associated with DDP sensitivity in cervical cancer cells, and Stat1 silencing can increase the sensitivity to DDP and c-Myc expression of the cells. PMID: 25613616 [PubMed - in process]
Source: Journal of Southern Medical University - January 20, 2015 Category: Universities & Medical Training Authors: Lei RL, Xiao SS, Xue M Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research