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The Vav3 oncogene enhances the malignant potential of prostate cancer cells under chronic hypoxia
Conclusions: Our results demonstrate that Vav3 plays a crucial role in prostate cancer growth and malignant behavior, thus revealing a novel potential therapeutic target.
Source: Urologic Oncology: Seminars and Original Investigations - February 11, 2013 Category: Urology & Nephrology Authors: Kenichi Hirai, Takeo Nomura, Mutsushi Yamasaki, Toru Inoue, Takahiro Narimatsu, Ph.D. Chisato Nakada, Ph.D. Yoshiyuki Tsukamoto, Keiko Matsuura, Fuminori Sato, Masatsugu Moriyama, Hiromitsu Mimata Tags: Clinical - Prostate Source Type: research

The Vav3 oncogene enhances the malignant potential of prostate cancer cells under chronic hypoxia.
CONCLUSIONS: Our results demonstrate that Vav3 plays a crucial role in prostate cancer growth and malignant behavior, thus revealing a novel potential therapeutic target. PMID: 23403204 [PubMed - as supplied by publisher]
Source: Urologic Oncology - February 8, 2013 Category: Urology & Nephrology Authors: Hirai K, Nomura T, Yamasaki M, Inoue T, Narimatsu T, Chisato Nakada PD, Yoshiyuki Tsukamoto PD, Matsuura K, Sato F, Moriyama M, Mimata H Tags: Urol Oncol Source Type: research