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GSE108262 Comparison of STEEL siRNA-treated and control siRNA-treated human endothelial cells
Contributors : Philip A Marsden ; H S ManSeries Type : Expression profiling by arrayOrganism : Homo sapiensTo determine the role of STEEL in endothelial cell (EC) gene regulation, gene expression analysis was conducted on control and STEEL siRNA-treated human dermal microvascular endothelial cells (HMVECs) and human umbilical vein endothelial cells (HUVECs). A total of 225 protein-coding genes were downregulated and 80 were upregulated when both EC types were grouped for analysis. In HMVEC alone, 544 protein-coding genes were downregulated and 218 were upregulated. In HUVEC alone, 177 protein-coding genes were downregulate...
Source: GEO: Gene Expression Omnibus - March 30, 2018 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research

GSE115341 Expression data from bladder cancer cells T24 - treated with G9a siRNA or negative control siRNA
Contributors : Jun Yan ; Jingya SunSeries Type : Expression profiling by arrayOrganism : Homo sapiensTarget genes regulated by G9a in bladder cancer cells T24In this dataset, we include the expression data obtained from bladder cancer cells T24 treated with G9a siRNA or negative control siRNA. These data are used to obtain genes that are differentially expressed in response to G9a konckdown.
Source: GEO: Gene Expression Omnibus - May 29, 2019 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research

Gold-Installed Biostable Nanocomplexes for Tumor-Targeted siRNA Delivery In Vivo
Chem. Commun., 2015, Accepted ManuscriptDOI: 10.1039/C5CC05639J, CommunicationRoun Heo, Hong Yeol Yoon, Hyewon Ko, Jung Min Shin, Jueun Jeon, Yee Soo Chae, Young Mo Kang, Dukjoon Kim, Doo Sung Lee, Jae Hyung ParkThe key issues, associated with nanocarriers for small interfering RNAs (siRNAs), are their poor stability and lack of tumor targetability in vivo. To address these needs, we developed gold-installed polyethyleneimine/siRNA...The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - September 21, 2015 Category: Chemistry Authors: Roun Heo Source Type: research

Groove modification of siRNA duplex to elucidate siRNA-protein interactions using 7-bromo-7-deazaadenosine and 3-bromo-3-deazaadenosine as chemical probes
In this study, the logical chemical probes,... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - September 21, 2016 Category: Molecular Biology Authors: Noriko Saito Tarashima Source Type: research

Groove modification of siRNA duplexes to elucidate siRNA-protein interactions using 7-bromo-7-deazaadenosine and 3-bromo-3-deazaadenosine as chemical probes
Org. Biomol. Chem., 2016, Advance Article DOI: 10.1039/C6OB01866A, PaperNoriko Saito-Tarashima, Hirotaka Kira, Tomoya Wada, Kazuya Miki, Shiho Ide, Naoshi Yamazaki, Akira Matsuda, Noriaki Minakawa The chemical probes, comprising Br7C7A and Br3C3A, to investigate RNA-protein interactions were developed. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - September 28, 2016 Category: Molecular Biology Authors: Noriko Saito-Tarashima Source Type: research

Highly Efficient Photocontrolled Targeted Delivery of siRNA by a Cyclodextrin-Based Supramolecular Nanoassembly
In this study, we fabricated a binary supramolecular nanoassembly composed of α-cyclodextrin-modified hyaluronic acid and an azobenzene-modified diphenylalanine derivative with a positively charged imidazole group.This nanoassembly can bind with siRNA... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - February 29, 2020 Category: Chemistry Authors: Feng-Qing Li Source Type: research

Translation and validation of PubMed and Embase search filters for identification of systematic reviews, intervention studies, and observational studies in the field of first aid
CONCLUSIONS: We report validated filters to search for systematic reviews, observational studies, and intervention studies in guideline projects in PubMed and Embase.com.PMID:34858089 | PMC:PMC8608173 | DOI:10.5195/jmla.2021.1219
Source: J Med Libr Assoc AND... - December 3, 2021 Category: Databases & Libraries Authors: Bert Avau Hans Van Remoortel Emmy De Buck Source Type: research