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Total 24412 results found since Jan 2013.

Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental healthcare providers
CONCLUSIONS: None of the included studies measured the incidence of infection among dental healthcare providers. The studies measured only reduction in level of bacterial contamination in aerosols. None of the studies evaluated viral or fungal contamination. We have only low to very low certainty for all findings. We are unable to draw conclusions regarding whether there is a role for preprocedural mouth rinses in reducing infection risk or the possible superiority of one preprocedural rinse over another. Studies are needed that measure the effect of rinses on infectious disease risk among dental healthcare providers and o...
Source: Cochrane Database of Systematic Reviews - August 22, 2022 Category: General Medicine Authors: Sumanth Kumbargere Nagraj Prashanti Eachempati Martha Paisi Mona Nasser Gowri Sivaramakrishnan Tony Francis Jos H Verbeek Source Type: research

Integrating pharmacological evaluation and computational identification for deciphering the action mechanism of Yunpi-Huoxue-Sanjie formula alleviates diabetic cardiomyopathy
Conclusion: YP-SJ formula treats DCM by modulating targets that play a key role in autophagy, improving myocardial function through a multi-component, multi-level, multi-target, multi-pathway, and multi-mechanism approach.
Source: Frontiers in Pharmacology - September 5, 2022 Category: Drugs & Pharmacology Source Type: research

Cannabis-based medicines and medical cannabis for adults with cancer pain
CONCLUSIONS: There is moderate-certainty evidence that oromucosal nabiximols and THC are ineffective in relieving moderate-to-severe opioid-refractory cancer pain. There is low-certainty evidence that nabilone is ineffective in reducing pain associated with (radio-) chemotherapy in people with head and neck cancer and non-small cell lung cancer. There is low-certainty evidence that a single dose of synthetic THC analogues is not superior to a single low-dose morphine equivalent in reducing moderate-to-severe cancer pain. There is low-certainty evidence that CBD does not add value to specialist palliative care alone in the ...
Source: Cochrane Database of Systematic Reviews - June 7, 2023 Category: General Medicine Authors: Winfried H äuser Patrick Welsch Lukas Radbruch Emma Fisher Rae Frances Bell R Andrew Moore Source Type: research

Comparative analysis of web search trends between experts and public for medicinal herbs in Korea
Conclusion This study presents meaningful results concerning the similarities and differences in interest between experts and public for popular medicinal herbs in Korea. Contrary to the common assumption that there exists big different interest between experts and public, this study revealed that there is apparent similar interest between experts and public on popular medicinal herbs in Korea. Graphical abstract
Source: Journal of Ethnopharmacology - November 28, 2015 Category: Drugs & Pharmacology Source Type: research

Role of angiogenesis in adenomyosis-associated abnormal uterine bleeding and subfertility: a systematic review
AbstractBackgroundAdenomyosis commonly occurs with abnormal uterine bleeding (AUB) and is associated with subfertility and a higher miscarriage rate. Recent evidence showed abnormal vascularization in the endometrium in patients with adenomyosis, suggesting a role of angiogenesis in the pathophysiology of AUB and subfertility in adenomyosis and providing a possible treatment target.Objective and rationaleWe hypothesized that the level of abnormal vascularization and expression of angiogenic markers is increased in the ectopic and eutopic endometrium of adenomyosis patients in comparison with the endometrium of control pati...
Source: Human Reproduction Update - September 2, 2019 Category: OBGYN Source Type: research

Using Web searches to track interest in synthetic cannabinoids (aka ‘herbal incense’)
ConclusionsMany tools found within Google free services hold promise in providing a technique to identify emerging drug markets. We recommend continued surveillance of the Internet using the online tools presented in this brief report by both drug researchers and policy‐makers to identify the emerging trends in synthetic drugs' availability and interest.
Source: Drug and Alcohol Review - September 6, 2014 Category: Addiction Authors: Brenda Curtis, Kelly Alanis‐Hirsch, Övgü Kaynak, John Cacciola, Kathy Meyers, Anthony Thomas McLellan Tags: Brief Report Source Type: research

Value and influencing factors of valid Traditional Chinese Medicine compound prescription patents for mammary gland hyperplasia
CONCLUSIONS: The maintenance of valid patents for Traditional Chinese Medicine compound prescriptions for treating mammary gland hyperplasia is of great importance. The maintenance of such patents depends on many factors, such as the concentration of effective herbs, number of dependent claims, provision of new dosage forms and detailed experimental data, and transfer of patent rights.PMID:36378061 | DOI:10.19852/j.cnki.jtcm.2022.06.010
Source: Journal of Traditional Chinese Medicine - November 15, 2022 Category: Complementary Medicine Authors: Yang Xujie Pei Xiaohua Source Type: research