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Claims about food allergies
I find it is very difficult to trust written material on this topic, nonetheless here is a hypothesis I had not heard before: So why have our immune systems suddenly gone haywire? One theory notes that we (mostly) eradicated hookworms by the 1980s in the United States. And roundworms. And…#andrewvandam #rss
Source: Reuters: Health - September 17, 2023 Category: Consumer Health News Source Type: news
Selecting optimal air diving gradient factors for Belgian military divers: more conservative settings are not necessarily safer
CONCLUSIONS: For non-repetitive air dives, the optimal GF setting is GFLO 100, with only the GFHI parameter lowered to increase safety. No evidence was found that using the default GF setting (30/70) would lead to a safer decompression for air dives as deep as 60 metres of seawater; rather the opposite. Belgian Navy divers have been advised against using the default GF settings of the Shearwater Perdix dive computer and instead adopt symmetrical GF settings which is currently the optimal achievable approach considering the software constraints.PMID:37718300 | DOI:10.28920/dhm53.3.251-258
Source: Diving and Hyperbaric Medicine - September 17, 2023 Category: Sports Medicine Authors: Sven De Ridder Nathalie Pattyn Xavier Neyt Peter Germonpr é Source Type: research
American Podiatric Surgeons' Postoperative Multimodal Analgesic-Prescribing Practice: A 2019-2020 National Survey
CONCLUSIONS: Podiatric surgeons with fewer years in practice had increased odds of supplementing with an anticonvulsant. Approximately one-third of podiatric surgeons reported using some form of a nonopioid analgesic and an opioid in every scenario. The use of multimodal analgesics was associated with a reduction in the number of opioid dosage units prescribed at the time of surgery and may be a reasonable adjunct to current protocols.PMID:37717233 | DOI:10.7547/21-145
Source: Journal of the American Podiatric Medical Association - September 17, 2023 Category: Podiatry Authors: Brandon M Brooks Reed W R Bratches Ashley M Nettles Adam E Fleischer Bradley M Brooks Rachel H Albright Source Type: research
Dissemination and Implementation of a Community Health Worker Intervention for Disparities in Palliative Care (DeCIDE PC): a study protocol for a hybrid type 1 randomized controlled trial
DISCUSSION: We expect the DeCIDE PC intervention to improve integration of palliative care, reduce multilevel barriers to care, enhance clinic and patient linkage to resources, and ultimately improve palliative care outcomes for African American patients with advanced cancer. If found to be effective, the DeCIDE PC intervention may be a transformative model with the potential to guide large-scale adoption of promising strategies to improve palliative care use and decrease disparities in end-of-life care for African American patients with advanced cancer in the United States.TRIAL REGISTRATION: Registered on ClinicalTrials....
Source: Cancer Control - September 17, 2023 Category: Cancer & Oncology Authors: Amn Siddiqi Olivia Monton Alison Woods Taleaa Masroor Shannon Fuller Jill Owczarzak Gayane Yenokyan Lisa A Cooper Karen M Freund Thomas J Smith Jean S Kutner Kathryn L Colborn Robert Joyner Ronit Elk Fabian M Johnston Source Type: research
Evolution of Perioperative Pain Management in Shoulder Arthroplasty
Orthop Clin North Am. 2023 Oct;54(4):435-451. doi: 10.1016/j.ocl.2023.04.004. Epub 2023 Jun 20.ABSTRACTHistorically, opioids have been used as a primary conservative treatment for pain related to glenohumeral osteoarthritis (GHOA). However, this practice is concerning as it often leads to overuse, which has contributed to the current epidemic of addiction and overdoses in the United States. Studies have shown that preoperative opioid use is associated with higher complication rates and worse outcomes following surgery, particularly for shoulder arthroplasty. To address these concerns, perioperative pain management for shou...
Source: The Orthopedic Clinics of North America - September 17, 2023 Category: Orthopaedics Authors: Vani Sabesan Hans Lapica Carlos Fernandez Clyde Fomunung Source Type: research
American Podiatric Surgeons' Postoperative Multimodal Analgesic-Prescribing Practice: A 2019-2020 National Survey
CONCLUSIONS: Podiatric surgeons with fewer years in practice had increased odds of supplementing with an anticonvulsant. Approximately one-third of podiatric surgeons reported using some form of a nonopioid analgesic and an opioid in every scenario. The use of multimodal analgesics was associated with a reduction in the number of opioid dosage units prescribed at the time of surgery and may be a reasonable adjunct to current protocols.PMID:37717233 | DOI:10.7547/21-145
Source: Journal of the American Podiatric Medical Association - September 17, 2023 Category: Podiatry Authors: Brandon M Brooks Reed W R Bratches Ashley M Nettles Adam E Fleischer Bradley M Brooks Rachel H Albright Source Type: research
Analgesic Trends in the Management of Pain Following Total Knee Arthroplasty: A Comparison of Peri-Articular Infiltration, Adductor Canal Block, and Adjuvant Treatment for Posterior Knee Pain
Orthop Clin North Am. 2023 Oct;54(4):369-376. doi: 10.1016/j.ocl.2023.05.004. Epub 2023 Jul 5.ABSTRACTThe rising number of total knee arthroplasties (TKA's) in the United States increases demand for perioperative pain modalities, which can promote early mobilization and discharge. Over the decades, a focus has shifted from opioid-dominant regimens to motor-sparing multimodal protocols, which have not only improved pain scores and reduced opioid consumption but also improved overall patient outcomes. In this article, we briefly review the evolution of post-operative pain management in patients undergoing TKA and summarize t...
Source: The Orthopedic Clinics of North America - September 17, 2023 Category: Orthopaedics Authors: Rutuja R Sikachi Brett Campbell Ezra Kassin Giles R Scuderi Joseph Marino Source Type: research
Evolution of Perioperative Pain Management in Shoulder Arthroplasty
Orthop Clin North Am. 2023 Oct;54(4):435-451. doi: 10.1016/j.ocl.2023.04.004. Epub 2023 Jun 20.ABSTRACTHistorically, opioids have been used as a primary conservative treatment for pain related to glenohumeral osteoarthritis (GHOA). However, this practice is concerning as it often leads to overuse, which has contributed to the current epidemic of addiction and overdoses in the United States. Studies have shown that preoperative opioid use is associated with higher complication rates and worse outcomes following surgery, particularly for shoulder arthroplasty. To address these concerns, perioperative pain management for shou...
Source: The Orthopedic Clinics of North America - September 17, 2023 Category: Orthopaedics Authors: Vani Sabesan Hans Lapica Carlos Fernandez Clyde Fomunung Source Type: research
Analgesic Trends in the Management of Pain Following Total Knee Arthroplasty: A Comparison of Peri-Articular Infiltration, Adductor Canal Block, and Adjuvant Treatment for Posterior Knee Pain
Orthop Clin North Am. 2023 Oct;54(4):369-376. doi: 10.1016/j.ocl.2023.05.004. Epub 2023 Jul 5.ABSTRACTThe rising number of total knee arthroplasties (TKA's) in the United States increases demand for perioperative pain modalities, which can promote early mobilization and discharge. Over the decades, a focus has shifted from opioid-dominant regimens to motor-sparing multimodal protocols, which have not only improved pain scores and reduced opioid consumption but also improved overall patient outcomes. In this article, we briefly review the evolution of post-operative pain management in patients undergoing TKA and summarize t...
Source: The Orthopedic Clinics of North America - September 17, 2023 Category: Orthopaedics Authors: Rutuja R Sikachi Brett Campbell Ezra Kassin Giles R Scuderi Joseph Marino Source Type: research
Evolution of Perioperative Pain Management in Shoulder Arthroplasty
Orthop Clin North Am. 2023 Oct;54(4):435-451. doi: 10.1016/j.ocl.2023.04.004. Epub 2023 Jun 20.ABSTRACTHistorically, opioids have been used as a primary conservative treatment for pain related to glenohumeral osteoarthritis (GHOA). However, this practice is concerning as it often leads to overuse, which has contributed to the current epidemic of addiction and overdoses in the United States. Studies have shown that preoperative opioid use is associated with higher complication rates and worse outcomes following surgery, particularly for shoulder arthroplasty. To address these concerns, perioperative pain management for shou...
Source: The Orthopedic Clinics of North America - September 17, 2023 Category: Orthopaedics Authors: Vani Sabesan Hans Lapica Carlos Fernandez Clyde Fomunung Source Type: research
Analgesic Trends in the Management of Pain Following Total Knee Arthroplasty: A Comparison of Peri-Articular Infiltration, Adductor Canal Block, and Adjuvant Treatment for Posterior Knee Pain
Orthop Clin North Am. 2023 Oct;54(4):369-376. doi: 10.1016/j.ocl.2023.05.004. Epub 2023 Jul 5.ABSTRACTThe rising number of total knee arthroplasties (TKA's) in the United States increases demand for perioperative pain modalities, which can promote early mobilization and discharge. Over the decades, a focus has shifted from opioid-dominant regimens to motor-sparing multimodal protocols, which have not only improved pain scores and reduced opioid consumption but also improved overall patient outcomes. In this article, we briefly review the evolution of post-operative pain management in patients undergoing TKA and summarize t...
Source: The Orthopedic Clinics of North America - September 17, 2023 Category: Orthopaedics Authors: Rutuja R Sikachi Brett Campbell Ezra Kassin Giles R Scuderi Joseph Marino Source Type: research
Selecting optimal air diving gradient factors for Belgian military divers: more conservative settings are not necessarily safer
CONCLUSIONS: For non-repetitive air dives, the optimal GF setting is GFLO 100, with only the GFHI parameter lowered to increase safety. No evidence was found that using the default GF setting (30/70) would lead to a safer decompression for air dives as deep as 60 metres of seawater; rather the opposite. Belgian Navy divers have been advised against using the default GF settings of the Shearwater Perdix dive computer and instead adopt symmetrical GF settings which is currently the optimal achievable approach considering the software constraints.PMID:37718300 | DOI:10.28920/dhm53.3.251-258
Source: Diving and Hyperbaric Medicine - September 17, 2023 Category: Sports Medicine Authors: Sven De Ridder Nathalie Pattyn Xavier Neyt Peter Germonpr é Source Type: research
American Podiatric Surgeons' Postoperative Multimodal Analgesic-Prescribing Practice: A 2019-2020 National Survey
CONCLUSIONS: Podiatric surgeons with fewer years in practice had increased odds of supplementing with an anticonvulsant. Approximately one-third of podiatric surgeons reported using some form of a nonopioid analgesic and an opioid in every scenario. The use of multimodal analgesics was associated with a reduction in the number of opioid dosage units prescribed at the time of surgery and may be a reasonable adjunct to current protocols.PMID:37717233 | DOI:10.7547/21-145
Source: Journal of the American Podiatric Medical Association - September 17, 2023 Category: Podiatry Authors: Brandon M Brooks Reed W R Bratches Ashley M Nettles Adam E Fleischer Bradley M Brooks Rachel H Albright Source Type: research
Selecting optimal air diving gradient factors for Belgian military divers: more conservative settings are not necessarily safer
CONCLUSIONS: For non-repetitive air dives, the optimal GF setting is GFLO 100, with only the GFHI parameter lowered to increase safety. No evidence was found that using the default GF setting (30/70) would lead to a safer decompression for air dives as deep as 60 metres of seawater; rather the opposite. Belgian Navy divers have been advised against using the default GF settings of the Shearwater Perdix dive computer and instead adopt symmetrical GF settings which is currently the optimal achievable approach considering the software constraints.PMID:37718300 | DOI:10.28920/dhm53.3.251-258
Source: Diving and Hyperbaric Medicine - September 17, 2023 Category: Sports Medicine Authors: Sven De Ridder Nathalie Pattyn Xavier Neyt Peter Germonpr é Source Type: research
Initial versus early switch to targeted therapy during first-line treatment among patients with biomarker-positive advanced or metastatic non-small cell lung cancer in the United States
CONCLUSION: In both unadjusted and adjusted analyses, there were no differences in the clinical outcomes observed among patients with a/mNSCLC in this study. This study found that initiating chemotherapy with an early switch to targeted therapy (within 56 days) of receiving biomarker positive results may be an acceptable strategy for a patient for whom immediate care is needed.PMID:37717466 | DOI:10.1016/j.ctarc.2023.100761
Source: Cell Research - September 17, 2023 Category: Cytology Authors: Lisa M Hess Patrick Peterson Tomoko Sugihara Naleen Raj Bhandari Peter M Krein Anthony Sireci Source Type: research
