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Total 422 results found since Jan 2013.

A quick algorithmic review on management of viral infectious diseases in pediatric solid organ transplant recipients
Front Pediatr. 2023 Sep 4;11:1252495. doi: 10.3389/fped.2023.1252495. eCollection 2023.ABSTRACTPediatric solid organ transplant is a life-saving procedure for children with end-stage organ failure. Viral infections are a common complication following pediatric solid organ transplantation (SOT), which can lead to increased morbidity and mortality. Pediatric solid organ transplant recipients are at an increased risk of viral infections due to their immunosuppressed state. The most commonly encountered viruses include cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus (HSV), varicella-zoster virus (VZV), ad...
Source: Herpes - September 21, 2023 Category: Infectious Diseases Authors: Marjan Moghadamnia Hamid Eshaghi Hosein Alimadadi Simin Dashti-Khavidaki Source Type: research

Antiviral therapy of coronavirus disease 2019 (COVID-19)
J Formos Med Assoc. 2023 Sep 2:S0929-6646(23)00342-X. doi: 10.1016/j.jfma.2023.08.029. Online ahead of print.ABSTRACTThe coronavirus disease 2019 (COVID-19) pandemic has reached a turning point. The non-pharmaceutical interventions for preventing COVID-19 are lifting. Vaccination uptake is increasing in general, but this strategy is continuously challenged by the rapid evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Of note, the Omicron subvariants spread globally for at least one year, and the most recently developed subvariants show strong immune evasion to preexisting immunity, either from pre...
Source: J Formos Med Assoc - September 4, 2023 Category: General Medicine Authors: Pao-Yu Chen Jann-Tay Wang Shan-Chwen Chang Source Type: research

Treatment and prevention of influenza in geriatric patients
Expert Rev Clin Pharmacol. 2023 Aug 1. doi: 10.1080/17512433.2023.2243221. Online ahead of print.ABSTRACTINTRODUCTION: Older adults are the most vulnerable population to the effects of influenza. These patients have age-related characteristics that make response to both infection and therapeutics different than younger patients.AREAS COVERED: Influenza vaccination and antiviral therapy are the foundational approach to preventing and treating influenza in geriatric patients. Older adults should receive one of three enhanced vaccines before influenza season beings. There are five antivirals used in influenza. Geriatric patie...
Source: Pharmacological Reviews - August 1, 2023 Category: Drugs & Pharmacology Authors: Marilyn N Bulloch Source Type: research

Past, present, and future of long-term treatment for hepatitis B virus
World J Gastroenterol. 2023 Jul 7;29(25):3964-3983. doi: 10.3748/wjg.v29.i25.3964.ABSTRACTThe estimated world prevalence of hepatitis B virus (HBV) infection is 316 million. HBV infection was identified in 1963 and nowadays is a major cause of cirrhosis and hepatocellular carcinoma (HCC) despite universal vaccination programs, and effective antiviral therapy. Long-term administration of nucleos(t)ide analogues (NA) has been the treatment of choice for chronic hepatitis B during the last decades. The NA has shown a good safety profile and high efficacy in controlling viral replication, improving histology, and decreasing th...
Source: World Journal of Gastroenterology - July 21, 2023 Category: Gastroenterology Authors: Teresa Broquetas Jos é A Carrión Source Type: research