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Antineoplastic Effects of Ankaferd Hemostat
CONCLUSION: ABS alters cell metabolism and cell cycle. ABS has antineoplastic role on cancer cells. The expanding context of ABS compromises anti-infective, antineoplastic, and wound healing features. ABS may also be used for the palliative, adjuvant, neoadjuvant, or supportive use by interventional radiology procedures for the treatment of solid tumors. Future controlled studies are necessary to clarify the pleiotropic role of ABS like antineoplastic, antithrombotic, anti-inflammatory, anti-infective, antifungal, and antioxidative effects.PMID:35958818 | PMC:PMC9363200 | DOI:10.1155/2022/2665903
Source: Biomed Res - August 12, 2022 Category: Research Authors: Umit Yavuz Malkan Ibrahim Celalettin Haznedaroglu Source Type: research

Biomimetic hydroxyapate/polydopamine composites with good biocompatibility and efficiency for uncontrolled bleeding
J Biomed Mater Res B Appl Biomater. 2021 Apr 13. doi: 10.1002/jbm.b.34849. Online ahead of print.ABSTRACTUncontrolled bleeding is thought to be the most deadly cause of pre-hospital, traffic, and military accidents death. However, the popular commercial hemostats can only realize the hemostasis of mild bleeding. Therefore, we developed polydopamine (PDA) composite materials (PMs), which applied hydroxyapatite as the parent body. The PMs were produced via lyophilization and functionalized with amino, phenol hydroxyls groups, which endowed hydrophobicity to materials. This ensured a high aggregation ability of blood cells to...
Source: Biomed Res - April 13, 2021 Category: Research Authors: Mengxiang Gong Chenyu Liu Chunyu Liu Lingyi Wang Farishta Shafiq Xia Liu Guozhen Sun Qiling Song Weihong Qiao Source Type: research

Use of hemostatic agents for surgical bleeding in laparoscopic partial nephrectomy: Biomaterials perspective.
Abstract In recent years, there was an abrupt increase in the incidence of renal tumors, which prompt up the appearance of cutting-edge technology, including minimally invasive and organ-preserving approaches, such as laparoscopic partial nephrectomy (LPN). LPN is an innovative technique used to treat small renal masses that have been gaining popularity in the last few decades due to its promissory results. However, the bleeding control remains the main challenge since the majority of currently available hemostatic agents (HAs) used in other surgical specialities are inefficient in LPN. This hurried the search for...
Source: Biomed Res - May 25, 2020 Category: Research Authors: Pacheco M, Barros AA, Aroso IM, Autorino R, Lima E, Silva JM, Reis RL Tags: J Biomed Mater Res B Appl Biomater Source Type: research

Thermal Treatment Stimulus on Erythrocyte Compatibility and Hemostatic Behaviour of One-Dimensional Bioactive Nano-Structures.
This study identifies the role and significance of heat treatment parameters on blood compatibility and hemostatic performances. Bioactive nanomaterials step-annealed at 550 °C and 600 °C enhances the biocompatibility due to the liberation of nitrate content. This also develops the anisotropic structures such as needle-like and rod-like appearances that positively improve the erythrocyte compatibility. Different stable crystalline phases such as NaCaPO4 , Na2 Ca2 Si3 O9 and Na1.8 Ca1.1 Si6 O14 were observed for all the bioactive materials, while in the case of 800 °C phase transition of Na3 CaPSiO7 was perceived along w...
Source: Biomed Res - May 2, 2020 Category: Research Authors: Chitra S, Bargavi P, Chandran RR, Balakumar S Tags: J Biomed Mater Res A Source Type: research

Use of Gelatin Sponge Affects Postoperative Morbidity In Cesarean Section Patients.
CONCLUSIONS Delay in recovery of bowel motility may be due to the local hypersensitivity reaction caused by GS and/or dislocation of this local hemostat. Women who receive gelatin sponge treatment during CS should be monitored closely for the recovery of postoperative intestinal motility. PMID: 28258978 [PubMed - in process]
Source: Medical Science Monitor - March 5, 2017 Category: Research Tags: Med Sci Monit Source Type: research