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A History of General Refrigeration
Ancient societies figured out that hypothermia was useful for hemorrhage control, but it was Hippocrates who realized that body heat could be a diagnostic tool. He caked his patients in mud, deducing that warmer areas dried first.
Typhoid fever, the plague of Athens in 400 BC and the demise of the Jamestown Colony in the early 1600s, led Robert Boyle to attempt to cure it around 1650 by dunking patients in ice-cold brine. This is likely the first application of therapeutic hypothermia, but it failed to lower the 30 to 40 percent mortality rate. One hundred years later, James Currie tried to treat fevers by applying hot,...
Source: Spontaneous Circulation - March 31, 2015 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Funtabulously Frivolous Friday Five 201
LITFL • Life in the Fast Lane Medical Blog
LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 201, courtesy of Dr Hakan Yaman from RFDS.
Question 1
What is the rate of severe permanent TBI in the Asterix comics, 0%, 25%, 50% or 90%?
http://www.asterix.com/the-collection/albums/asterix-and-the-picts.html
+ Reveal the Funtabulous Answer
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Source: Life in the Fast Lane - August 10, 2017 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five asterix CRP Death dying Felty's syndrome fingernail GCS head injury hospital Pain pencil RA rheumatoid arthritis TBI Source Type: blogs
Funtabulously Frivolous Friday Five 221
LITFL • Life in the Fast Lane Medical Blog
LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 220.
Question 1
The Adverts, a UK punk band in the 1970s wrote the song “Looking through Gary Gilmore’s eyes”. Who is Gary Gilmore and why would two people be looking through his eyes?
+ Reveal the Funtabulous Answer
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Source: Life in the Fast Lane - January 5, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five aspergillum Ayahuasca basket case cornea transplant garlic gary gilmore lone star tick meat allergy otomycosis paul simon shaman swimmers ear Source Type: blogs
Funtabulously Frivolous Friday Five 229
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 229 – musical medial conditions from http://www.songfacts.com.
Question 1
“I stare into
Some great abyss
And calculate
The things I’d miss
If I could only
Make some sense of this.”
Sheryl Crow is singing about her experience undergoing treatmen...
Source: Life in the Fast Lane - March 9, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five ACDC breast cancer cardiac arrest gonorrhoea heart attack heroin Leonard Cohen Madness radiation song Sheryl Crow Spiderbite The Flaming Lips The Jack Source Type: blogs
Third International Conference on End of Life Law, Ethics, Policy, and Practice
Here is the program for the Third International Conference on End of Life Law, Ethics, Policy, and Practice. Pretty awesome.
Thursday 7 March, 2019
08.30-09.00Registration & Welcome Coffee
09.00-09.10Welcome by the Chair of the Scientific Committee – Kenneth Chambaere (BE)
09.10-09.30Introduction by an external speaker (TBC)
Plenary 1: Latest developments in assisted dying around the world
09.30-10.00Developments in European countries – Agnes van der Heide (NL)
10.00-10.30Recent developments and the future of MAiD in Canada – Jocelyn Downie (CAN)
10.30-11.00A review of developmen...
Source: blog.bioethics.net - January 18, 2019 Category: Medical Ethics Authors: Thaddeus Mason Pope, JD, PhD Tags: Health Care syndicated Source Type: blogs
Fight Aging! Newsletter, May 2nd 2016
This study is the first CAR T-cell trial to infuse patients with an even mixture of two types of T cells (helper and killer cells, which work together to kill cancer). With the assurance that each patient gets the same mixture of cells, the researchers were able to come to conclusions about the effects of administering different doses of cells.
In 27 of 29 participants whose responses were evaluated a few weeks after the infusion, a high-sensitivity test could detect no trace of their cancer in their bone marrow. The CAR T cells eliminated cancers anywhere in the body they appeared. Of the two participants who did n...
Source: Fight Aging! - May 1, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Most Pressing Issues In Bioethics
Who owns medical and genetic data? How to regulate gene editing? Where is the boundary of enhancing physical or cognitive human capabilities? What to do with biological differences widening the gap of the haves and have-nots? Could we define where is the boundary to augment life? Will we sue robots or algorithms for medical malpractice? With the constant advancement of technology, unprecedented moral, ethical and legal concerns are surfacing. Channeling them into substantial debates will get us closer to their fair solution step by step. Here, we collected the most pressing issues in bioethics.
Bioethicists
of the world...
Source: The Medical Futurist - March 26, 2019 Category: Information Technology Authors: nora Tags: Bioethics Cyborgization Genomics bioethical data debate DNA future gene editing genetic genetics Innovation legal longevity medical medical data moral sex sexuality technology Source Type: blogs
Fight Aging! Newsletter, June 21st 2021
This study showed that the leakage of this mitochondrial nucleic material may occur as a result of mitochondrial dysfunction, which may involve genetic mutations in genes encoding mitochondrial proteins or incomplete degradation of mitochondrial dsDNA in the lysosome - which is a 'degradation factory' of the cell. Upon the leakage into the cytoplasm, this undegraded dsDNA is detected by a 'foreign' DNA sensor of the cytoplasm (IFI16) which then triggers the upregulation of mRNAs encoding for inflammatory proteins."
Using a PD zebrafish model (gba mutant), the researchers demonstrated that a combination of PD-like ph...
Source: Fight Aging! - June 20, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A 100-Year-Old Martian In An Exoskeleton
The story of The Medical FuturistThe mission of a futuristThe most transformative technology: A.I.The mission of The Medical FuturistThe business modelCommunication of science to wide audiencesScience fiction and scienceData measurementData privacyAdvice to health policy-makersThe gap between the haves and have-nots Nightmare scenarios The future of the doctor-patient relationshipGenetics and gene editingMars and healthcare
What do archaeologists and futurists have in common? Why was the Internet underestimated as a technology to transform society while A.I. is over-hyped? What’s the most transformative concept in hea...
Source: The Medical Futurist - February 12, 2019 Category: Information Technology Authors: nora Tags: Great Thinkers Source Type: blogs
The Doctor Who Thwarted the Charge of the General Medical Council – Part 1
By SAURABH JHA
After Dr. Hadiza Bawa-Garba was convicted for manslaughter for delayed diagnosis of fatal sepsis in Jack Adcock, a six-year-old boy who presented to Leicester Royal Infirmary with diarrhea and vomiting, she was referred to the Medical Practitioners Tribunal (MPT). The General Medical Council (GMC) is the professional regulatory body for physicians. But the MPT determines whether a physician is fit to practice. Though the tribunal is nested within the GMC and therefore within an earshot of its opinions, it is a decision-making body which is theoretically independent of the GMC.
The tribunal met in 2017, 6 ...
Source: The Health Care Blog - August 5, 2018 Category: Consumer Health News Authors: at RogueRad Tags: NHS #BawaGarba @roguerad Source Type: blogs
Explain yourself, machine. Producing simple text descriptions for AI interpretability
We describe a feature, give a location, and then synthesise a conclusion. For example:
There is an irregular mass with microcalcification in the upper outer quadrant of the breast. Findings are consistent with malignancy.
You don’t need to understand the words I used here, but the point is that the features (irregular mass, microcalcification) are consistent with the diagnosis (breast cancer, malignancy). A doctor reading this report already sees internal consistency, and that reassures them that the report isn’t wrong. An common example of a wrong report could be:
Irregular mass or microcalcification. No ...
Source: The Health Care Blog - December 12, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech AI Luke Oakden-Rayner machine learning Radiology Source Type: blogs
