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Total 145 results found since Jan 2013.
P384 Expanding the role of tryptase from allergy to cancer?
Elevated serum tryptase values may be found in several conditions, including mastocytosis, myeloproliferative neoplasms, hypereosinophilic disorders, and myelodysplastic syndromes. Increased density of tissue mast cells is correlated with poor prognosis in lung adenocarcinoma as well as melanoma, gastric carcinoma, and breast cancer. While an elevated tryptase has been proposed as a biomarker in several hematologic malignancies including chronic myeloid leukemia, an elevated tryptase has not been previously reported in association with lung adenocarcinoma.
Source: Annals of Allergy, Asthma and Immunology - October 27, 2017 Category: Allergy & Immunology Authors: J. Hagan, T. Pongdee Source Type: research
Rapid Drug Desensitization with Chemotherapeutics (Platins, Taxanes, and Others): A Single-Center Retrospective Study
Conclusion: In our experience, 98.3% of 122 RDDs were completed. We found that RDD was safe and effective in this the largest series of RDD with chemotherapeutics in our country.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - March 20, 2019 Category: Allergy & Immunology Source Type: research
Modulatory Effects of Metformin Alone and in Combination with Cimetidine and Ibuprofen on T Cell-related Parameters in a Breast Cancer Model
Iran J Allergy Asthma Immunol. 2021 Sep 28;20(5):600-613. doi: 10.18502/ijaai.v20i5.7410.ABSTRACTMetformin, cimetidine, and ibuprofen separately exhibit immunomodulatory and anti-tumorigenic effects. Herein, the impacts of metformin alone and in combination with cimetidine/ibuprofen on some Th1- and regulatory T (Treg) cell-related parameters were evaluated using a breast cancer (BC) model. For establishing the BC model, four groups of Balb/c mice were challenged with the carcinoma cell line. After 11-30 days post-induction, they were treated intraperitoneally (with metformin (200 mg/kg), "metformin plus cimetidine (20 mg/...
Source: Iranian Journal of Allergy, Asthma and Immunology - October 19, 2021 Category: Allergy & Immunology Authors: Fereshteh Taghipour Omolbanin Oladpour Mohammad Taghi Rezayati Hossain Khorramdelazad Maryam Nemati Zahra Taghipour Javad Masoumi Zuhair Mohammad Hassan Abdollah Jafarzadeh Source Type: research
