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Total 103 results found since Jan 2013.

Efficacy of a Clinical Decision Rule to Enable Direct Oral Challenge in Patients With Low-Risk Penicillin Allergy: The PALACE Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, direct oral penicillin challenge in patients with a low-risk penicillin allergy was noninferior compared with standard-of-care skin testing followed by oral challenge. In patients with a low-risk history, direct oral penicillin challenge is a safe procedure to facilitate the removal of a penicillin allergy label.TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04454229.PMID:37459086 | DOI:10.1001/jamainternmed.2023.2986
Source: Cancer Control - July 17, 2023 Category: Cancer & Oncology Authors: Ana Maria Copaescu Sara Vogrin Fiona James Kyra Y L Chua Morgan T Rose Joseph De Luca Jamie Waldron Andrew Awad Jack Godsell Elise Mitri Belinda Lambros Abby Douglas Rabea Youcef Khoudja Ghislaine A C Isabwe Genevieve Genest Michael Fein Cristine Radojici Source Type: research

Description and accuracy of antibiotic allergy labels at North Shore Hospital
CONCLUSIONS: The prevalence of antibiotic specific allergies in our centre was similar to New Zealand and Australian statistics.1,2 Our study showed that a significant proportion of inpatients with a beta-lactam-specific allergy could be de-labelled on history or with a single dose challenge.PMID:37414075
Source: New Zealand Medical Journal - July 6, 2023 Category: General Medicine Authors: Liam D Kelly Tim Cutfield Kerry Read Source Type: research