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Population Health Management: principles, models and areas of application in public health
Acta Biomed. 2023 Aug 30;94(S3):e2023162. doi: 10.23750/abm.v94iS3.14554.ABSTRACTThere is no single model for Population Health Management (PHM) and different definitions have been proposed. All PHM models and definitions share the overall aim of improving population health and reduce healthcare costs. To achieve these objectives, PHM makes use of conceptual tools such as the Chronic Care Model and predictive medicine, and technical tools such as information systems and computational and record-linkage techniques to collect and analyse data. Using these tools, it makes it feasible to articulate PHM approaches in the follow...
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Lorenzo Blandi Leonardo Pegollo Leandro Gentile Anna Odone Source Type: research

Decolonizing Global Child Health Education for More Equitable and Culturally Safe Collaborations
Pediatr Ann. 2023 Sep;52(9):e344-e350. doi: 10.3928/19382359-20230720-07. Epub 2023 Sep 1.ABSTRACTGlobal health (GH) as an academic field is fraught with both historical and present systemic injustice, including unilateral partnerships; power asymmetry in grant funding and research agenda setting; lack of acknowledgment of contributions from low- and middle-income country collaborators; and disadvantageous bias toward low- and middle-income country institutions. Reflecting on the legacies of colonialism and White supremacy is vital for training pediatricians to actively work to improve the health of all children worldwide,...
Source: Pediatric Annals - September 11, 2023 Category: Pediatrics Authors: Viviane Tchonang Leuche Roberto Delgado-Zapata Lisa Umphrey Suet Kam Lam Kristin Cardiel Nunez Victor Musiime Amy Rule Source Type: research

Population Health Management: principles, models and areas of application in public health
Acta Biomed. 2023 Aug 30;94(S3):e2023162. doi: 10.23750/abm.v94iS3.14554.ABSTRACTThere is no single model for Population Health Management (PHM) and different definitions have been proposed. All PHM models and definitions share the overall aim of improving population health and reduce healthcare costs. To achieve these objectives, PHM makes use of conceptual tools such as the Chronic Care Model and predictive medicine, and technical tools such as information systems and computational and record-linkage techniques to collect and analyse data. Using these tools, it makes it feasible to articulate PHM approaches in the follow...
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Lorenzo Blandi Leonardo Pegollo Leandro Gentile Anna Odone Source Type: research

Decolonizing Global Child Health Education for More Equitable and Culturally Safe Collaborations
Pediatr Ann. 2023 Sep;52(9):e344-e350. doi: 10.3928/19382359-20230720-07. Epub 2023 Sep 1.ABSTRACTGlobal health (GH) as an academic field is fraught with both historical and present systemic injustice, including unilateral partnerships; power asymmetry in grant funding and research agenda setting; lack of acknowledgment of contributions from low- and middle-income country collaborators; and disadvantageous bias toward low- and middle-income country institutions. Reflecting on the legacies of colonialism and White supremacy is vital for training pediatricians to actively work to improve the health of all children worldwide,...
Source: Pediatric Annals - September 11, 2023 Category: Pediatrics Authors: Viviane Tchonang Leuche Roberto Delgado-Zapata Lisa Umphrey Suet Kam Lam Kristin Cardiel Nunez Victor Musiime Amy Rule Source Type: research

Population Health Management: principles, models and areas of application in public health
Acta Biomed. 2023 Aug 30;94(S3):e2023162. doi: 10.23750/abm.v94iS3.14554.ABSTRACTThere is no single model for Population Health Management (PHM) and different definitions have been proposed. All PHM models and definitions share the overall aim of improving population health and reduce healthcare costs. To achieve these objectives, PHM makes use of conceptual tools such as the Chronic Care Model and predictive medicine, and technical tools such as information systems and computational and record-linkage techniques to collect and analyse data. Using these tools, it makes it feasible to articulate PHM approaches in the follow...
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Lorenzo Blandi Leonardo Pegollo Leandro Gentile Anna Odone Source Type: research

Decolonizing Global Child Health Education for More Equitable and Culturally Safe Collaborations
Pediatr Ann. 2023 Sep;52(9):e344-e350. doi: 10.3928/19382359-20230720-07. Epub 2023 Sep 1.ABSTRACTGlobal health (GH) as an academic field is fraught with both historical and present systemic injustice, including unilateral partnerships; power asymmetry in grant funding and research agenda setting; lack of acknowledgment of contributions from low- and middle-income country collaborators; and disadvantageous bias toward low- and middle-income country institutions. Reflecting on the legacies of colonialism and White supremacy is vital for training pediatricians to actively work to improve the health of all children worldwide,...
Source: Pediatric Annals - September 11, 2023 Category: Pediatrics Authors: Viviane Tchonang Leuche Roberto Delgado-Zapata Lisa Umphrey Suet Kam Lam Kristin Cardiel Nunez Victor Musiime Amy Rule Source Type: research

Population Health Management: principles, models and areas of application in public health
Acta Biomed. 2023 Aug 30;94(S3):e2023162. doi: 10.23750/abm.v94iS3.14554.ABSTRACTThere is no single model for Population Health Management (PHM) and different definitions have been proposed. All PHM models and definitions share the overall aim of improving population health and reduce healthcare costs. To achieve these objectives, PHM makes use of conceptual tools such as the Chronic Care Model and predictive medicine, and technical tools such as information systems and computational and record-linkage techniques to collect and analyse data. Using these tools, it makes it feasible to articulate PHM approaches in the follow...
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Lorenzo Blandi Leonardo Pegollo Leandro Gentile Anna Odone Source Type: research

Decolonizing Global Child Health Education for More Equitable and Culturally Safe Collaborations
Pediatr Ann. 2023 Sep;52(9):e344-e350. doi: 10.3928/19382359-20230720-07. Epub 2023 Sep 1.ABSTRACTGlobal health (GH) as an academic field is fraught with both historical and present systemic injustice, including unilateral partnerships; power asymmetry in grant funding and research agenda setting; lack of acknowledgment of contributions from low- and middle-income country collaborators; and disadvantageous bias toward low- and middle-income country institutions. Reflecting on the legacies of colonialism and White supremacy is vital for training pediatricians to actively work to improve the health of all children worldwide,...
Source: Pediatric Annals - September 11, 2023 Category: Pediatrics Authors: Viviane Tchonang Leuche Roberto Delgado-Zapata Lisa Umphrey Suet Kam Lam Kristin Cardiel Nunez Victor Musiime Amy Rule Source Type: research

Second primary malignancies in patients with lymphoma in Denmark after high-dose chemotherapy and autologous haematopoietic stem-cell transplantation: a population-based, retrospective cohort study
Lancet Haematol. 2023 Sep 6:S2352-3026(23)00212-0. doi: 10.1016/S2352-3026(23)00212-0. Online ahead of print.ABSTRACTBACKGROUND: Second primary malignancies (SPMs) are known complications after chemotherapy, but the risk is not well characterised for patients with lymphoma treated with high-dose chemotherapy and autologous haematopoietic stem-cell transplantation (HSCT). We aimed to investigate the rate of SPMs in this population relative to matched control individuals from the general population.METHODS: In this retrospective, population-based cohort study, patients aged 18 years or older with an aggressive lymphoma who r...
Source: Cancer Control - September 9, 2023 Category: Cancer & Oncology Authors: Trine Trab Joachim Baech Lasse Hjort Jakobsen Simon Husby Marianne Tang Severinsen Sandra Eloranta Jette S G ørløv Judit M J ørgensen Sif Gudbrandsdottir Thomas Stauffer Larsen Peter Brown Kirsten Gr ønbæk Karin E Smedby Tarec C El-Galaly Source Type: research

Her work paved the way for blockbuster obesity drugs. Now, she ’s fighting for recognition
When Svetlana Mojsov heard the spring 2021 announcement, she was startled. The Canada Gairdner International Award, a prestigious biomedical research prize, would be bestowed on three scientists for work underpinning the diabetes and obesity drugs that have exploded in popularity in recent years. “I was really upset,” recalls Mojsov, a chemist at Rockefeller University. The Gairdner award marked the third time in 4 years that the same trio of scientists—Joel Habener at Massachusetts General Hospital (MGH), Daniel Drucker at the University of Toronto, and Jens Juul Holst at the University of Copenhagen—were hon...
Source: Science of Aging Knowledge Environment - September 8, 2023 Category: Geriatrics Source Type: research

Long-term esophageal cancer risk and distinct surveillance intervals after a single endoscopy screening: a multicentre population-based cohort study
This study aimed to assess long-term esophageal cancer (EC) incidence and mortality after a single endoscopy screening.METHODS: We included individuals at high risk of EC aged 40-69 years who underwent endoscopy screening in 2007-2012 at six centres in rural China and had a baseline diagnosis of negative endoscopy findings, mild dysplasia, or moderate dysplasia. Participants were followed up for EC incidence and mortality. Cumulative incidence and mortality rates of EC were estimated by Kaplan-Meier analyses. Cox regression models were used to calculate adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for as...
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: He Li Changfa Xia Siyi He Xinxin Yan Shaoli Zhang Yi Teng Maomao Cao Fan Yang Qianru Li Hengmin Ma Jinyi Zhou Shaokai Zhang Wanqing Chen Source Type: research

Effectiveness and safety of atezolizumab-bevacizumab in patients with unresectable hepatocellular carcinoma: a systematic review and meta-analysis
EClinicalMedicine. 2023 Aug 30;63:102179. doi: 10.1016/j.eclinm.2023.102179. eCollection 2023 Sep.ABSTRACTBACKGROUND: Atezolizumab-bevacizumab (atezo-bev) is recommended as first-line therapy for patients with unresectable hepatocellular carcinoma (uHCC). However, its effectiveness and safety in other populations, including those with Child-Turcotte-Pugh (CTP) class B cirrhosis, is unclear.METHODS: For this systematic review and meta-analysis, electronic databases, including PubMed, Embase, and Scopus, were searched from 1st May, 2020 till 5th October, 2022; the last date of access was January 31, 2023. Pooled progression-...
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Anand V Kulkarni Harshvardhan Tevethia Karan Kumar Madhumita Premkumar Mark D Muttaiah Atsushi Hiraoka Takeshi Hatanaka Toshifumi Tada Takashi Kumada Satoru Kakizaki Arndt Vogel Richard S Finn Padaki Nagaraja Rao Anjana Pillai Duvvur Nageshwar Reddy Amit Source Type: research

RUNX-3-expressing CAR T cells targeting glypican-3 in patients with heavily pretreated advanced hepatocellular carcinoma: a phase I trial
This study was funded by CARsgen Therapeutics Co., Ltd.PMID:37680942 | PMC:PMC10480529 | DOI:10.1016/j.eclinm.2023.102175
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Qihan Fu Yi Zheng Weijia Fang Qingwei Zhao Peng Zhao Lulu Liu You Zhai Zhou Tong Hangyu Zhang Meihua Lin Xudong Zhu Huamao Wang Yumeng Wang Zhen Liu Daijing Yuan Xuanwen Bao Wanwan Gao Xiaomeng Dai Zonghai Li Tingbo Liang Source Type: research