The contribution of EEG to assess and treat motor disorders in multiple sclerosis
CONCLUSIONS: We highlight some key EEG patterns in pwMS at rest and during movement, both suggesting an alteration or disruption of brain connectivity, more specifically involving sensorimotor networks.SIGNIFICANCE: Some of these EEG biomarkers of motor disturbance could be used to design future therapeutic strategies in MS based on neuromodulation approaches, or to predict the effects of motor training and rehabilitation in pwMS.PMID:38643612 | DOI:10.1016/j.clinph.2024.03.024 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 21, 2024 Category: Neurology Authors: Benjamin Bardel Samar S Ayache Jean-Pascal Lefaucheur Source Type: research

Electrode positioning errors reduce current dose for focal tDCS set-ups: Evidence from individualized electric field mapping
CONCLUSIONS: Precise positioning is crucial when using focal tDCS set-ups to avoid significant reductions of current dose in the intended target regions.SIGNIFICANCE: Our results highlight the urgent need to routinely implement methods for improving electrode positioning, minimization of electrode drift, verification of electrode positions before and/or after tDCS and also to consider positioning errors when investigating dose-response relationships, especially for focal set-ups.PMID:38643613 | DOI:10.1016/j.clinph.2024.03.031 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 21, 2024 Category: Neurology Authors: Filip Niemann Steffen Riemann Ann-Kathrin Hubert Daria Antonenko Axel Thielscher Andrew K Martin Nina Unger Agnes Fl öel Marcus Meinzer Source Type: research

Spatial and temporal properties of intra-operatively recorded spikes and high frequency oscillations in focal cortical dysplasia
CONCLUSIONS: A combined analysis of event numbers, ratios, and temporal relationships between spikes and HFOs may aid identifying epileptic tissue in epilepsy surgery.SIGNIFICANCE: This study shows a promising method for clinically relevant properties of events, closely associated with FCD.PMID:38643614 | DOI:10.1016/j.clinph.2024.03.038 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 21, 2024 Category: Neurology Authors: Eline V Schaft Dongqing Sun Maryse A van 't Klooster Dorien van Blooijs Paul L Smits Willemiek J E M Zweiphenning Peter H Gosselaar Cyrille H Ferrier Maeike Zijlmans RESPect database study group Source Type: research

Detection of seizure onset in childhood absence epilepsy
CONCLUSION: The performance of the proposed unsupervised methods is equivalent to that of the supervised ones. The use of only four electrodes makes the pipeline suitable to be embedded in a wearable device.SIGNIFICANCE: The proposed pipelines perform early detection of absence seizures, which constitutes a prerequisite for a closed-loop system.PMID:38644110 | DOI:10.1016/j.clinph.2024.03.034 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 21, 2024 Category: Neurology Authors: M Aud'hui A Kachenoura M Yochum A Kaminska R Nabbout F Wendling M Kuchenbuch P Benquet Source Type: research

The contribution of EEG to assess and treat motor disorders in multiple sclerosis
CONCLUSIONS: We highlight some key EEG patterns in pwMS at rest and during movement, both suggesting an alteration or disruption of brain connectivity, more specifically involving sensorimotor networks.SIGNIFICANCE: Some of these EEG biomarkers of motor disturbance could be used to design future therapeutic strategies in MS based on neuromodulation approaches, or to predict the effects of motor training and rehabilitation in pwMS.PMID:38643612 | DOI:10.1016/j.clinph.2024.03.024 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 21, 2024 Category: Neurology Authors: Benjamin Bardel Samar S Ayache Jean-Pascal Lefaucheur Source Type: research

Electrode positioning errors reduce current dose for focal tDCS set-ups: Evidence from individualized electric field mapping
CONCLUSIONS: Precise positioning is crucial when using focal tDCS set-ups to avoid significant reductions of current dose in the intended target regions.SIGNIFICANCE: Our results highlight the urgent need to routinely implement methods for improving electrode positioning, minimization of electrode drift, verification of electrode positions before and/or after tDCS and also to consider positioning errors when investigating dose-response relationships, especially for focal set-ups.PMID:38643613 | DOI:10.1016/j.clinph.2024.03.031 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 21, 2024 Category: Neurology Authors: Filip Niemann Steffen Riemann Ann-Kathrin Hubert Daria Antonenko Axel Thielscher Andrew K Martin Nina Unger Agnes Fl öel Marcus Meinzer Source Type: research

Spatial and temporal properties of intra-operatively recorded spikes and high frequency oscillations in focal cortical dysplasia
CONCLUSIONS: A combined analysis of event numbers, ratios, and temporal relationships between spikes and HFOs may aid identifying epileptic tissue in epilepsy surgery.SIGNIFICANCE: This study shows a promising method for clinically relevant properties of events, closely associated with FCD.PMID:38643614 | DOI:10.1016/j.clinph.2024.03.038 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 21, 2024 Category: Neurology Authors: Eline V Schaft Dongqing Sun Maryse A van 't Klooster Dorien van Blooijs Paul L Smits Willemiek J E M Zweiphenning Peter H Gosselaar Cyrille H Ferrier Maeike Zijlmans RESPect database study group Source Type: research

Detection of seizure onset in childhood absence epilepsy
CONCLUSION: The performance of the proposed unsupervised methods is equivalent to that of the supervised ones. The use of only four electrodes makes the pipeline suitable to be embedded in a wearable device.SIGNIFICANCE: The proposed pipelines perform early detection of absence seizures, which constitutes a prerequisite for a closed-loop system.PMID:38644110 | DOI:10.1016/j.clinph.2024.03.034 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 21, 2024 Category: Neurology Authors: M Aud'hui A Kachenoura M Yochum A Kaminska R Nabbout F Wendling M Kuchenbuch P Benquet Source Type: research

Predictive value of Blink reflex and facial corticobulbar motor evoked potential in cerebellopontine angle tumor surgery
CONCLUSIONS: BR can compensate for the deficiencies of the FCoMEPs. The combination of BR and FCoMEPs can be used in CPA tumor surgery.SIGNIFICANCE: The study first proposed an optimal cut-off value of BR amplitude deterioration (50.0%) for predicting postoperative eyelid closure deficits in patients undergoing CPA tumor surgery.PMID:38642482 | DOI:10.1016/j.clinph.2024.03.033 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 20, 2024 Category: Neurology Authors: Jiajia Liu Xing Fan Lirui Yang Xiaorong Tao Yanwen Jin Ke Li Jun Yang Hui Qiao Source Type: research

Responsive neurostimulation as a therapy for epilepsy following new-onset refractory status epilepticus: Case series and review of the literature
CONCLUSIONS: Our single-center experience of three cases suggests that RNS is a safe and potentially effective treatment for DRE following NORSE.SIGNIFICANCE: This article reports outcomes of the largest case series of NORSE patients treated with RNS. Since patients with NORSE are at high risk of adverse neuropsychiatric and cognitive sequelae beyond seizures, a unique strength of RNS over other surgical options is the ability to distinguish ictal or peri-ictal from non-epileptic events.PMID:38640819 | DOI:10.1016/j.clinph.2024.03.032 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 19, 2024 Category: Neurology Authors: Audrey Oliger Caleb Nerison Hao Tan Ahmed Raslan Lia Ernst Proleta Datta Marissa Kellogg Source Type: research

How coil misalignment and mispositioning in transcranial magnetic stimulation affect the stimulation strength at the target
Clin Neurophysiol. 2024 Apr 10;162:159-161. doi: 10.1016/j.clinph.2024.03.037. Online ahead of print.NO ABSTRACTPMID:38640820 | DOI:10.1016/j.clinph.2024.03.037 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 19, 2024 Category: Neurology Authors: Max Koehler Thomas Kammer Stefan Goetz Source Type: research

Abnormal modulation of the blink reflex in functional sensory loss
Clin Neurophysiol. 2024 Apr 10;162:162-164. doi: 10.1016/j.clinph.2024.04.001. Online ahead of print.NO ABSTRACTPMID:38640821 | DOI:10.1016/j.clinph.2024.04.001 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 19, 2024 Category: Neurology Authors: Markus Kofler Moritz Haibach Manuela Kofler Michael Thurner Elke Pucks-Faes Viviana Versace Source Type: research

Understanding the variability of the electrophysiologic laryngeal adductor reflex
CONCLUSIONS: cR1 latencies show high analytical precision for measurements. Delayed onset, difficult to elicit, desynchronized and unsustained cR1, and absence of cR2 signal an abnormal eLAR.SIGNIFICANCE: Understanding the variability and behavior of normal and abnormal eLAR under IGA can aid in the interpretation of its changes during monitoring.PMID:38631074 | DOI:10.1016/j.clinph.2024.03.019 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 17, 2024 Category: Neurology Authors: Mirela V Simon Seward B Rutkove Long Ngo Corey R Fehnel Alvin S Das Todd Sarge Somnath Bose Magdy Selim Sandeep Kumar Source Type: research

Harnessing neuromodulation to tackle rumination: Trait-dependent effects of theta burst stimulation
Clin Neurophysiol. 2024 Apr 5:S1388-2457(24)00099-3. doi: 10.1016/j.clinph.2024.03.027. Online ahead of print.NO ABSTRACTPMID:38631923 | DOI:10.1016/j.clinph.2024.03.027 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 17, 2024 Category: Neurology Authors: Ryouhei Ishii Keigo Shiraiwa Source Type: research

Investigating delirium in stroke with an EEG lens: Focal lesions with global impact?
Clin Neurophysiol. 2024 Apr 9:S1388-2457(24)00100-7. doi: 10.1016/j.clinph.2024.03.028. Online ahead of print.NO ABSTRACTPMID:38631924 | DOI:10.1016/j.clinph.2024.03.028 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - April 17, 2024 Category: Neurology Authors: Erika L Ju árez Martínez Eyal Kimchi Source Type: research