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Discussion Guide for the Laures Article
Am J Crit Care. 2023 Sep 1;32(5):355-356. doi: 10.4037/ajcc2023696.NO ABSTRACTPMID:37652878 | DOI:10.4037/ajcc2023696
Source: American Journal of Critical Care - August 31, 2023 Category: Nursing Authors: Grant A Pignatiello Source Type: research
Underscreening in concentrated electrolytes: Re-entrant swelling in polyelectrolyte brushes
Phys. Chem. Chem. Phys., 2023, Accepted Manuscript DOI: 10.1039/D3CP02206D, PaperHayden Robertson, Gareth Elliott, Andrew R. J. Nelson, Anton Pierre Le Brun, Grant Bruce Webber, Stuart W Prescott, Vincent S. J. Craig, Erica J Wanless, Joshua Willott Hypersaline environments are ubiquitous in nature and are found in myriad technological processes. Recent empirical studies have revealed a significant discrepancy between the predicted and observed screening lengths at high... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - August 31, 2023 Category: Chemistry Authors: Hayden Robertson Source Type: research
Improved Triplex-Forming Isoorotamide PNA Nucleobases for A-U Recognition of RNA Duplexes
Chemistry. 2023 Aug 30:e202302390. doi: 10.1002/chem.202302390. Online ahead of print.ABSTRACTFour new isoorotamide (Io) containing PNA nucleobases were designed for A-U recognition of double helical RNA. New PNA monomers were prepared efficiently and incorporated into PNA 9-mers for binding A-U in a PNA:RNA2 triplex. Isothermal titration calorimetry and UV thermal melting experiments revealed slightly improved binding affinity for singly-modified PNA compared to known A-binding nucleobases. Molecular dynamics simulations provided further insights into binding of Io bases in the triple helix. Together, data revealed intere...
Source: Chemistry - August 30, 2023 Category: Chemistry Authors: John M Talbott Brandon R Tessier Emily E Harding Grant D Walby Kyle J Hess Vladislavs Baskevics Martins Katkevics Eriks Rozners James A MacKay Source Type: research
Phylogeny-wide analysis of G-protein coupled receptors in social amoebas and implications for the evolution of multicellularity
Discussion Our phylogenetic analysis suggests that GPCR families 1, 2 and 6 already diverged early in the Amoebozoa, whereas families 3 and 5 expanded later within the dictyostelids. The family 6 cAMP receptors that have experimentally supported roles in multicellular development in dictyostelids ( carA-carD; tasA/B) originated at the root of all dictyostelids and only have weakly associated homologs in Physarum polycephalum. Our analysis identified candidate GPCRs which have evolved in the dictyostelids and could have been co-opted for multicellular development.PMID:37645274 | PMC:PMC10445921 | DOI:10.12688/openreseurope.15250.2
Source: Cell Research - August 30, 2023 Category: Cytology Authors: Grant Hall Sarah Kelly Pauline Schaap Christina Schilde Source Type: research
Understanding disruptions in cancer care to reduce increased cancer burden
CONCLUSIONS: This study provides an understanding of the factors associated with cancer care disruption and what patients need to return to care. Results may inform outreach and engagement strategies to reduce delayed cancer screenings and encourage returning to cancer care.FUNDING: This study was supported by the National Cancer Institute's Administrative Supplements for P30 Cancer Center Support Grants (P30CA091842-18S2 and P30CA091842-19S4). Kia L. Davis, Lisa Klesges, Sarah Humble, and Bettina Drake were supported by the National Cancer Institute's P50CA244431 and Kia L. Davis was also supported by the Breast Cancer Re...
Source: Cancer Control - August 29, 2023 Category: Cancer & Oncology Authors: Kia L Davis Nicole Ackermann Lisa M Klesges Nora Leahy Callie Walsh-Bailey Sarah Humble Bettina Drake Vetta L Sanders Thompson Source Type: research
< em > Rhodiola Rosea < /em > as an Adaptogen to Enhance Exercise Performance: A Review of the Literature
Br J Nutr. 2023 Aug 29:1-27. doi: 10.1017/S0007114523001988. Online ahead of print.ABSTRACTRhodiola rosea (RR) is a plant whose bioactive components may function as adaptogens, thereby increasing resistance to stress and improving overall resilience. Some of these effects may influence exercise performance and adaptations. Based on studies of rodents, potential mechanisms for the ergogenic effects of RR include modulation of energy substrate stores and use, reductions in fatigue and muscle damage, and altered antioxidant activity. At least 16 investigations in humans have explored the potential ergogenicity of RR. These st...
Source: The British Journal of Nutrition - August 29, 2023 Category: Nutrition Authors: Grant M Tinsley Andrew R Jagim Gregory D M Potter Dan Garner Andrew J Galpin Source Type: research
Fatalities in Oil and Gas Extraction Database, an Industry-Specific Worker Fatality Surveillance System - United States, 2014-2019
This report describes the creation of the Fatalities in Oil and Gas Extraction (FOG) database, presents initial findings from the first 6 years of data collection (2014-2019), highlights ways that FOG data have been used, and describes the benefits and challenges of maintaining the surveillance system.PERIOD COVERED: 2014-2019.DESCRIPTION OF SYSTEM: In 2013, the National Institute for Occupational Safety and Health (NIOSH) created the FOG database, a surveillance system comprising an industry-specific worker fatality database. NIOSH researchers worked with OGE partners to establish inclusion criteria for the database and d...
Source: MMWR Surveill Summ - August 29, 2023 Category: Epidemiology Authors: Kaitlin C Wingate Alejandra Ramirez-Cardenas Ryan Hill Sophia Ridl Kyla Hagan-Haynes Source Type: research
< em > Rhodiola Rosea < /em > as an Adaptogen to Enhance Exercise Performance: A Review of the Literature
Br J Nutr. 2023 Aug 29:1-27. doi: 10.1017/S0007114523001988. Online ahead of print.ABSTRACTRhodiola rosea (RR) is a plant whose bioactive components may function as adaptogens, thereby increasing resistance to stress and improving overall resilience. Some of these effects may influence exercise performance and adaptations. Based on studies of rodents, potential mechanisms for the ergogenic effects of RR include modulation of energy substrate stores and use, reductions in fatigue and muscle damage, and altered antioxidant activity. At least 16 investigations in humans have explored the potential ergogenicity of RR. These st...
Source: The British Journal of Nutrition - August 29, 2023 Category: Nutrition Authors: Grant M Tinsley Andrew R Jagim Gregory D M Potter Dan Garner Andrew J Galpin Source Type: research
