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Specialty: Urology & Nephrology

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Total 98061 results found since Jan 2013.

When is the best surgical time for benign prostate hyperplasia treatment?
Asian J Androl. 2023 Aug 15. doi: 10.4103/aja202339. Online ahead of print.NO ABSTRACTPMID:37695245 | DOI:10.4103/aja202339
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Lucas Mira Gon C ássio Riccetto Source Type: research

Decreased AKAP4/PKA signaling pathway in high DFI sperm affects sperm capacitation
This study intends to explore the reason for the decreased fertilization rate observed in high sperm DFI (H-DFI) patients during IVF-ET. In addition, the study investigates the expression of AKAP, protein kinase A regulatory subunit (PKARII), and SPA17 between H-DFI and low sperm DFI (L-DFI) patients. SPA17 at the transcriptional level is abnormal, the translational level increases in H-DFI patients, and the expression of AKAP4/PKARII protein decreases. H2O2 has been used to simulate oxidative stress damage to spermatozoa during the formation of sperm DFI. It indicates that H2O2 increases the expression of sperm SPA17 prot...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Kun Zhang Xiu-Hua Xu Jian Wu Ning Wang Gang Li Gui-Min Hao Jin-Feng Cao Source Type: research

Corrigendum to "Rescue of male infertility through correcting a genetic mutation causing meiotic arrest in spermatogonial stem cells"
Asian J Androl. 2023 Aug 22. doi: 10.4103/aja202344. Online ahead of print.NO ABSTRACTPMID:37695243 | DOI:10.4103/aja202344
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Ying-Hua Wang Meng Yan Xi Zhang Xin-Yu Liu Yi-Fu Ding Chong-Ping Lai Ming-Han Tong Jin-Song Li Source Type: research

Prostate health index can stratify patients with Prostate Imaging Reporting and Data System score 3 lesions on magnetic resonance imaging to reduce prostate biopsies
Asian J Androl. 2023 Aug 22. doi: 10.4103/aja202332. Online ahead of print.ABSTRACTWe aim to evaluate prostate health index as an additional risk-stratification tool in patients with Prostate Imaging Reporting and Data System score 3 lesions on multiparametric magnetic resonance imaging. Men with biochemical or clinical suspicion of having prostate cancer who underwent multiparametric magnetic resonance imaging in two tertiary centers (Queen Mary Hospital and Princess Margaret Hospital, Hong Kong, China) between January 2017 and June 2022 were included. Ultrasound-magnetic resonance imaging fusion biopsies were performed a...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: John Shung-Lai Leung Wai-Kit Ma Brian Sze-Ho Ho Stacia Tsun-Tsun Chun Rong Na Yongle Zhan Chi-Yuen Ng Chi-Ho Ip Ada Tsui-Lin Ng Yiu-Chung Lam Source Type: research

What is the effect of Tribulus terrestris on testicular morphology and sperm production? An experimental study in the rat model
The objective of this study was to investigate whether treatment with Tribulus terrestris (Tt) has any impact on the testicular morphology and function in a rodent model. Twenty male rats were divided into a control group and a group receiving 100 mg kg-1 body weight of Tt supplementation. After 40 days of experiment, the animals were submitted to euthanasia; epididymal tail spermatozoa were collected; and spermatozoa concentration, motility, and viability were analyzed. In addition, testicles were collected and processed for histomorphometrical analyses. Data were compared using the Student's t-test and considered signifi...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Marcello Henrique Araujo Da Silva Gabriela Faria Buys-Gon çalves Jo ão Henrique Duque Reis Estrada Francisco Jos é Barcellos Sampaio Diogo Benchimol de Souza Source Type: research

Psychological consequences of a diagnosis of infertility in men: a systematic analysis
Asian J Androl. 2023 Aug 22. doi: 10.4103/aja202334. Online ahead of print.ABSTRACTAlmost half of infertility cases involve male infertility. Understanding the consequence of a diagnosis of male infertility, as a sole or partial contributor to the couples' infertility, to the mental health of men is required to ensure clinical care meets their psychological needs. The aim of this systematic analysis was to synthesize the evidence regarding whether men diagnosed with male factor infertility experience greater psychological distress than (1) men described as fertile and (2) men in couples with other infertility diagnoses. On...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Sarah N Biggs Jane Halliday Karin Hammarberg Source Type: research

Nitro-oleic acid ameliorates erectile dysfunction in a streptozotocin-induced rat model of diabetes by inhibiting oxidative stress and apoptosis and activating the NO/cGMP pathway
In conclusion, NO2-OA treatment partially improved erectile function in DMED rats through mechanisms that included inhibition of oxidative stress, activation of the NO/cGMP pathway, and a reduction in apoptosis.PMID:37695220 | DOI:10.4103/aja202331
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Chang-Bo Zhao Wei-Bo Chen Wen-Zhen Wang Fang-Xin Gong Cui-Qin Fan Ye Li Tian Lan Wen-Jing Wang Ming-Zhen Yuan Source Type: research

The impact of the COVID-19 pandemic on erectile function in Chinese CP/CPPS patients
This study aimed to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on erectile function in Chinese patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). A retrospective study was conducted on 657 CP/CPPS patients who visited The Third Xiangya Hospital of Central South University (Changsha, China) from November 2018 to November 2022. Patients were divided into two groups based on the timeline before and after the COVID-19 outbreak in China. The severity of CP/CPPS, penile erection status, anxiety, and depression was evaluated using the National Institutes of Health-Chronic Pro...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Wei-Jie Song Ji-Wei Huang Yuan Liu Wei Ding Zhi Long Le-Ye He Source Type: research

Sperm acrosin activity may be a useful factor in choosing between ICSI and IVF for infertile male patients
Asian J Androl. 2023 Aug 22. doi: 10.4103/aja202337. Online ahead of print.ABSTRACTThe clinical applications of acrosin activity are limited. We analyzed 61 578 male partners in infertile couples who visited the outpatient department of the Reproductive and Genetic Hospital of CITIC-Xiangya (Changsha, China) between August 2014 and December 2019 to determine the reference ranges and thresholds for acrosin activity in infertile Chinese men; to determine whether correlations exist between acrosin activity and age, sperm concentration, sperm morphology, or sperm motility; and to evaluate whether acrosin activity could serve a...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Ye-Na Hu Liang Hu Xin-Yu Yin Huan Zhang Yang-Qin Peng Gang Liu Ge Lin Wei-Na Li Source Type: research

Psychological consequences of a diagnosis of infertility in men: a systematic analysis
Asian J Androl. 2023 Aug 22. doi: 10.4103/aja202334. Online ahead of print.ABSTRACTAlmost half of infertility cases involve male infertility. Understanding the consequence of a diagnosis of male infertility, as a sole or partial contributor to the couples' infertility, to the mental health of men is required to ensure clinical care meets their psychological needs. The aim of this systematic analysis was to synthesize the evidence regarding whether men diagnosed with male factor infertility experience greater psychological distress than (1) men described as fertile and (2) men in couples with other infertility diagnoses. On...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Sarah N Biggs Jane Halliday Karin Hammarberg Source Type: research

Nitro-oleic acid ameliorates erectile dysfunction in a streptozotocin-induced rat model of diabetes by inhibiting oxidative stress and apoptosis and activating the NO/cGMP pathway
In conclusion, NO2-OA treatment partially improved erectile function in DMED rats through mechanisms that included inhibition of oxidative stress, activation of the NO/cGMP pathway, and a reduction in apoptosis.PMID:37695220 | DOI:10.4103/aja202331
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Chang-Bo Zhao Wei-Bo Chen Wen-Zhen Wang Fang-Xin Gong Cui-Qin Fan Ye Li Tian Lan Wen-Jing Wang Ming-Zhen Yuan Source Type: research

The impact of the COVID-19 pandemic on erectile function in Chinese CP/CPPS patients
This study aimed to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on erectile function in Chinese patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). A retrospective study was conducted on 657 CP/CPPS patients who visited The Third Xiangya Hospital of Central South University (Changsha, China) from November 2018 to November 2022. Patients were divided into two groups based on the timeline before and after the COVID-19 outbreak in China. The severity of CP/CPPS, penile erection status, anxiety, and depression was evaluated using the National Institutes of Health-Chronic Pro...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Wei-Jie Song Ji-Wei Huang Yuan Liu Wei Ding Zhi Long Le-Ye He Source Type: research

Sperm acrosin activity may be a useful factor in choosing between ICSI and IVF for infertile male patients
Asian J Androl. 2023 Aug 22. doi: 10.4103/aja202337. Online ahead of print.ABSTRACTThe clinical applications of acrosin activity are limited. We analyzed 61 578 male partners in infertile couples who visited the outpatient department of the Reproductive and Genetic Hospital of CITIC-Xiangya (Changsha, China) between August 2014 and December 2019 to determine the reference ranges and thresholds for acrosin activity in infertile Chinese men; to determine whether correlations exist between acrosin activity and age, sperm concentration, sperm morphology, or sperm motility; and to evaluate whether acrosin activity could serve a...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Ye-Na Hu Liang Hu Xin-Yu Yin Huan Zhang Yang-Qin Peng Gang Liu Ge Lin Wei-Na Li Source Type: research

Comparison of cytokine levels in prostatic secretion between the IIIa and IIIb subtypes of prostatitis
Asian J Androl. 2023 Aug 22. doi: 10.4103/aja202336. Online ahead of print.ABSTRACTChronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), also known as National Institutes of Health (NIH) type III prostatitis, is a common disorder with an unclear etiology and no known curative treatments. Based on the presence or absence of leukocytes in expressed prostatic secretion (EPS), CP/CPPS is classified further into IIIa (inflammatory) and IIIb (noninflammatory) subtypes. However, the severity of symptoms is not entirely consistent with the white blood cell (WBC) count. Following the preliminary finding of a link between infl...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Cheng-Lin Han Yu-Xuan Deng Peng Hu Bin-Tao Hu Tao Wang Ji-Hong Liu Ming-Chao Li Source Type: research

Using the DFree device for balanced bladder management
CONCLUSIONS: The DFree ultrasonic sensor is a new technical tool in the treatment of bladder dysfunctions. Improving specific technical details could increase the user-friendliness as well as the usefulness of the device.PMID:37696293 | DOI:10.1055/a-2107-8947
Source: Aktuelle Urologie - September 11, 2023 Category: Urology & Nephrology Authors: Sandra Helen Sch önburg Sebastian Hofstetter Christian Buhtz Denny Paulicke Dietrich Stoevesandt Patrick Jahn Karsten Schwarz Georgios Gakis Source Type: research