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Fight Aging! Newsletter, August 7th 2023
In conclusion, here, we demonstrate a novel mechanism for ESC-EVs to protect cells from senescence. However, whether ESC-EVs rejuvenate aged mice via miR-15b-5p and miR-290a-5p remains unknown. Next, we plan to use miR-15b-5p and miR-290a-5p antagonists while treating aged mice with ESC-EVs to further investigate the mechanism by which ESC-EVs resist aging in vivo.
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Fatty Acid Metabolism as a Commonality in Different Approaches to Slowing Aging
https://www.fightaging.org/archives/2023/08/fatty-acid-metabolism-as-a-commonality-in-different-approaches-to-slowing-aging/
It seems...
Source: Fight Aging! - August 6, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Kidney Disease in Childhood Cancer Survivors Treated With Radiation Therapy: A Comprehensive PENTEC Genitourinary Review
CONCLUSIONS: In patients with Wilms tumor, the risk of toxicity from 10.5 Gy of WAI is low. For 12 Gy fractionated TBI with various mixtures of chemotherapy, the risk of severe toxicity is low, but low-grade toxicity is not uncommon. Partial kidney data are limited and toxicity is associated heavily with the use of nephrotoxic chemotherapeutic agents. Our efforts demonstrate the need for improved data gathering, systematic follow-up, and reporting in future clinical studies. Current radiation dose used for Wilms tumor and TBI appear to be safe; however, efforts in effective kidney-sparing TBI and WAI regimens may reduce th...
Source: Health Physics - July 15, 2023 Category: Physics Authors: Matthew M Poppe An Tai X Allen Li Moyed Miften Arthur Olch Lawrence B Marks Bilal Mazhar Qureshi Sheri L Spunt Margarett Shnorhavorian Geoff Nelson Cecile Ronckers John Kalapurakal Brian Marples Louis S Constine Arthur K Liu Source Type: research
Rhombencephalitis and longitudinal extensive myelitis associated with dinutuximab use in high-risk neuroblastoma
CONCLUSIONS: Awareness of the radiological findings of dinutuximab toxicity will lead to prompt diagnosis and treatment.PMID:37395971 | DOI:10.24953/turkjped.2022.598
Source: The Turkish Journal of Pediatrics - July 3, 2023 Category: Pediatrics Authors: F ırat Atak G üzide Burça Aydın İbrahim Öncel Sibel Öz Kader Karl ı Oğuz Source Type: research
