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Urologic provider experiences in transitioning spina bifida patients from pediatric to adult care
ConclusionsPotential solutions to improve the urologic care of this population suggest additional national provider resources, standardized guidelines, multidisciplinary collaboration, access to care, and an advanced-training pathway to improve care of adult patients with spina bifida.
Source: World Journal of Urology - January 16, 2019 Category: Urology & Nephrology Source Type: research

Missing trial results: analysis of the current publication rate of studies in pediatric dialysis from 2003 to 2020
ConclusionsCurrently, only 52.8% of all investigated studies in pediatric dialysis have available results, and the overall median time to publication did not meet FDA requirements. This might introduce a publication bias into the field, and it might negatively impact clinical decision-making in this critical subspecialty of pediatric medicine.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information
Source: Pediatric Nephrology - December 13, 2022 Category: Urology & Nephrology Source Type: research

Assessment of Worldwide Acute Kidney Injury, Renal Angina and Epidemiology in Critically Ill Children (AWARE): study protocol for a prospective observational study
DiscussionThe Assessment of Worldwide Acute Kidney Injury, Renal Angina and Epidemiology (AWARE) study, creates the first prospective international pediatric all cause AKI data warehouse and biologic sample repository, providing a broad and invaluable resource for critical care nephrologists seeking to study risk factors, prediction, identification, and treatment options for a disease syndrome with high associated morbidity affecting a significant proportion of hospitalized children.Trial registrationClinicalTrials.gov: NCT01987921
Source: BMC Nephrology - February 26, 2015 Category: Urology & Nephrology Authors: Rajit BasuAhmad KaddourahTara TerrellTheresa MottesPatricia ArnoldJudd JacobsJennifer AndringaStuart Goldsteinon behalf of the Prospective Pediatric AKI Research Group (ppAKI) Source Type: research

Acute kidney injury after heart transplant in young children: risk factors and outcomes
Conclusions AKI was common after heart transplant and associated with more complicated early post-transplant course. Lower baseline eCCl was associated with lower incidence of AKI; this merits further investigation. The association of pre-operative inotropes with less AKI may reflect a pathophysiological mechanism or be a surrogate for clinical factors and management prior to transplant. Avoiding high tacrolimus levels may be a modifiable risk factor for AKI.
Source: Pediatric Nephrology - February 24, 2016 Category: Urology & Nephrology Source Type: research

In their own words: the value of qualitative research to improve the care of children with chronic kidney disease
This article will outline how qualitative research can generate relevant evidence to inform practice and policy in children with CKD, provide an overview of qualitative methods and introduce a framework to appraise qualitative research. More evidence derived from qualitative research is needed to inform shared decision-making and the development of interventions and policies that address the preferences and priorities of children with CKD and their families. Ultimately, this strategy may help to improve the outcomes that they regard as critical to their care.
Source: Pediatric Nephrology - August 25, 2017 Category: Urology & Nephrology Source Type: research

Sirtuins play critical and diverse roles in acute kidney injury
AbstractAcute kidney injury (AKI) is an extremely common medical affliction affecting both adult and pediatric patients resulting from hypoxic, nephrotoxic, and septic insults affecting approximately 20% of all hospital patients and up to 50% of patients in the intensive care unit. There are currently no therapeutics for patients who suffer AKI. Much recent work has focused on designing and implementing therapeutics for AKI. This review focuses on a family of enzymes known as sirtuins that play critical roles in regulating many cellular and biological functions. There are 7 mammalian sirtuins (SIRT1 –7) that play roles i...
Source: Pediatric Nephrology - January 7, 2021 Category: Urology & Nephrology Source Type: research

Critical analysis of acute kidney injury in pediatric COVID-19 patients in the intensive care unit
ConclusionAKI has shown to be a negative prognostic factor in adult patients with COVID-19 and now also in the pediatric cohort with high incidence and mortality rates. Additionally, our findings show a strong comparison in epidemiology between adult and pediatric COVID-19 patients; however, they need to be confirmed with additional data and studies.Graphical abstract
Source: Pediatric Nephrology - August 18, 2021 Category: Urology & Nephrology Source Type: research

Barriers in transitioning urologic patients from pediatric to adult care
As the advances in medicine continue to emerge, more children with congenital or pediatric-onset chronic urologic conditions are surviving well into adulthood. This imposes an ever rising there is a need for adequate transition of these patients from pediatric to adult care. Despite position statements from multiple heath care organizations and several models proposed in literature, different issues and gaps in urologic transition continue to exist. Major barriers in this transition are adolescence, a challenging time that is characterized by impulsive behavior and risk taking, and the longstanding relation between both pa...
Source: Journal of Pediatric Urology - December 21, 2020 Category: Urology & Nephrology Authors: Wietse P. Claeys, Joshua.D. Roth, Piet Hoebeke Tags: Review Article Source Type: research

Documenting urine output for pediatric urology patients in the post-anesthesia care unit: a quality improvement initiative
Close monitoring and documentation of urine output (UOP) after urologic surgery is a nursing standard of care in the post-anesthesia care unit (PACU). UOP is a critical piece of information for surgeons and anesthesiologists to provide safe quality patient care. The electronic medical record (EMR) is used to communicate this information between members of the care team. Initial review at our institution confirmed only 31.3% of children recovering in the PACU after urologic surgery had a numerical value for UOP documented in the EMR.
Source: Journal of Pediatric Urology - December 22, 2021 Category: Urology & Nephrology Authors: Anja Zann, Renee Wolfe, Julie Samora Source Type: research

Acute Kidney Injury in Pediatric Patients with COVID-19; Clinical Features and Outcome
CONCLUSION: Kidneys are among the major organs affected by COVID-19. Although kidney abnormalities resolve in the majority of pediatric COVID-19 infections, particular attention should be paid to serum creatinine and electrolyte levels in patients affected by COVID-19, particularly children with a history of malnutrition and kidney disorders. DOI: 10.52547/ijkd.7151.PMID:36739487
Source: Iranian Journal of Kidney Diseases - February 5, 2023 Category: Urology & Nephrology Authors: Mahbubeh Mirzaee Mahnaz Jamee Masoumeh Mohkam Fatemeh Abdollah Gorji Mitra Khalili Sedigheh Rafiei Tabatabaei Abdollah Karimi Shahnaz Armin Roxana Mansour Ghanaie Seyed Alireza Fahimzad Zahra Pournasiri Seyed Mohammad Taghi Hosseini Tabatabaei Reza Dalira Source Type: research

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