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Specialty: Urology & Nephrology

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Total 124459 results found since Jan 2013.

Whole exome sequencing: a state-of-the-art approach for defining (and exploring!) genetic landscapes in pediatric nephrology
AbstractThe genesis of whole exome sequencing as a powerful tool for detailing the protein coding sequence of the human genome was conceptualized based on the availability of next-generation sequencing technology and knowledge of the human reference genome. The field of pediatric nephrology enriched with molecularly unsolved phenotypes is allowing the clinical and research application of whole exome sequencing to enable novel gene discovery and provide amendment of phenotypic misclassification. Recent studies in the field have informed us that newer high-throughput sequencing techniques are likely to be of high yield when ...
Source: Pediatric Nephrology - March 21, 2018 Category: Urology & Nephrology Source Type: research

Trends in pediatric urologic consultations in a tertiary care hospital setting
There is growing interest in the general activities of a pediatric urologist, whose specialty remains young in the spectrum of modern, organized medicine. Unplanned activities, which are more commonly referred to as consultations, can represent significant additional workload for the urologist seeing scheduled clinic patients or completing elective operative cases.
Source: Journal of Pediatric Urology - August 8, 2017 Category: Urology & Nephrology Authors: K.O. Rove, J.C. Warncke, V.M. Vemulakonda Source Type: research

Psychosocial considerations and recommendations for care of pediatric patients on dialysis
This article aims to address this gap by providing a review of the pediatric literature examining psychosocial functioning in patients treated with dialysis, as well as recommendations for specific psychosocial concerns. Overall recommendations for care include screening for anxiety and depression, referral to pediatric psychologists for evidence-based intervention, utilization of child life specialists, opportunities to promote social functioning, neuropsychological evaluation and school programming, ong oing support in preparing for transition to adult care, and periodic measure of quality of life. Together, these sugges...
Source: Pediatric Nephrology - March 25, 2020 Category: Urology & Nephrology Source Type: research

Inpatient Dialysis Planning During the COVID-19 Pandemic: A Single-Center Experience and Review of the Literature.
Conclusion: Planning for an expected surge in hospitalized patients requiring RRT demands coordination between critical care, dialysis and nursing services as well as community and hospital providers to make certain there are adequate dialysis resources. Our experience suggests that continuous dialysis is in greatest demand early in the illness, and that plans to increase supplies should be put in place. But, planning should also focus on unforeseen hospital-specific infrastructure shortages that can develop over time and hamper intermittent dialysis delivery to all patients who require treatment. PMID: 33116756 [PubMed]
Source: International Journal of Nephrology and Renovascular Disease - October 31, 2020 Category: Urology & Nephrology Tags: Int J Nephrol Renovasc Dis Source Type: research

Needs of children with a chronic bladder in preparation for transfer to adult care
Conclusion: Although overall self-perceived knowledge is sufficient, the trust in and personal relationship with the pediatric urologist formed the greatest obstruction to successful transition. These findings have been used to improve support during transition by creating a transition protocol.
Source: Journal of Pediatric Urology - June 13, 2012 Category: Urology & Nephrology Authors: M. van der Toorn, H. Cobussen-Boekhorst, K. Kwak, K. D'hauwers, R.P.E. de Gier, W.F.J. Feitz, B.B.M. Kortmann Tags: Research Articles Source Type: research

Ultrasound diagnosis of multicystic dysplastic kidney: Is a confirmatory nuclear medicine scan necessary?
It is critical to differentiate between a multicystic dysplastic kidney (MCDK) and a kidney with severe hydronephrosis as the treatment varies significantly. We designed a study to compare renal ultrasound (RUS) to nuclear medicine (NM) scan in the diagnosis of MCDK, in order to determine if RUS can be used for the definitive diagnosis of MCKD without use of NM scan.
Source: Journal of Pediatric Urology - May 1, 2014 Category: Urology & Nephrology Authors: Benjamin M. Whittam, Adam Calaway, Konrad M. Szymanski, Aaron E. Carroll, Rosalie Misseri, Martin Kaefer, Richard C. Rink, Boaz Karmazyn, Mark P. Cain Source Type: research

Outcome of acute kidney injury in pediatric patients admitted to the intensive care unit.
CONCLUSION: Severe AKI predicted high mortality in critically ill children. PMID: 25412199 [PubMed - in process]
Source: Clinical Nephrology - November 22, 2014 Category: Urology & Nephrology Authors: Shalaby M, Khathlan N, Safder O, Fadel F, Farag YM, Singh AK, Kari JA Tags: Clin Nephrol Source Type: research

Heightened graft failure risk during emerging adulthood and transition to adult care
Abstract Emerging adulthood, defined as the interval between 18 and 25 years of age, is a socially-defined developmental stage. Although people in this age group appear physically mature, brain maturation is not complete until the end of this period. Perhaps due to this immaturity and a resulting inferior ability to manage chronic illness emerging adults with a variety of chronic health conditions are at a high risk for adverse outcomes. In this review I will summarize evidence that emerging adulthood constitutes a high-risk period for kidney transplant recipients, and consider the possible reasons for the spike...
Source: Pediatric Nephrology - February 19, 2015 Category: Urology & Nephrology Source Type: research

A Society for Pediatric Urology Workforce Survey on the Current Perceptions of Oncology Care by Pediatric Urologists: A Report from the Pediatric Urologic Oncology Working Group of the Society for Pediatric Urology
Data are lacking on the current perception of oncology care among pediatric urologists. Thus, we developed, pilot tested and administered a survey on this topic to SPU (Society for Pediatric Urology) members.
Source: The Journal of Urology - November 8, 2016 Category: Urology & Nephrology Authors: Nicholas G. Cost, Fernando A. Ferrer, Armando J. Lorenzo, Margarett Shnorhavorian, Kathleen Kieran, Jonathan C. Routh, Michael L. Ritchey, Jonathan H. Ross Tags: Pediatric Supplement Article Source Type: research

Adherence in pediatric kidney transplant recipients: solutions for the system
AbstractNon-adherence remains a significant problem among pediatric (and adult) renal transplant recipients. Non-adherence among solid organ transplant recipients results in US$15 –100 million annual costs. Estimates of non-adherence range from 30 to 70% among pediatric patients. Research demonstrates that a 10% decrement in adherence is associated with 8% higher hazard of graft failure and mortality. Focus has begun to shift from patient factors that impact adherence to th e contributing healthcare and systems factors. The purpose of this review is to describe problems within the systems implicated in non-adherence and ...
Source: Pediatric Nephrology - February 5, 2018 Category: Urology & Nephrology Source Type: research

Exit site and tunnel infections in children on chronic peritoneal dialysis: findings from the Standardizing Care to Improve Outcomes in Pediatric End Stage Renal Disease (SCOPE) Collaborative
ConclusionsExit site infections occur at an annualized rate of 0.25, typically well into the dialysis course. Younger patient age and documented review of site care are associated with lower ESI rates. Although most ESIs resolve, hospitalization is frequent, and tunnel involvement/catheter loss complicate outcomes.
Source: Pediatric Nephrology - May 10, 2018 Category: Urology & Nephrology Source Type: research

Effect of BMI on allograft function and survival in pediatric renal transplant recipients
ConclusionsObesity is prevalent in pediatric renal transplant recipients, and obese, but not overweight or underweight, pediatric renal transplant recipients have an increased risk of allograft failure. Implementation of effective obesity interventions in pediatric renal transplant recipients is of critical importance to improve longevity of the renal allograft.
Source: Pediatric Nephrology - June 26, 2018 Category: Urology & Nephrology Source Type: research

Acute kidney injury prediction models: current concepts and future strategies
Purpose of review Acute kidney injury (AKI) is a critical condition associated with poor patient outcomes. We aimed to review the current concepts and future strategies regarding AKI risk prediction models. Recent findings Recent studies have shown that AKI occurs frequently in patients with common risk factors and certain medical conditions. Prediction models for AKI risk have been reported in medical fields such as critical care medicine, surgery, nephrotoxic agent exposure, and others. However, practical, generalizable, externally validated, and robust AKI prediction models remain relatively rare. Further efforts t...
Source: Current Opinion in Nephrology and Hypertension - October 8, 2019 Category: Urology & Nephrology Tags: DIAGNOSTICS AND TECHNIQUES: Edited by Maarten W. Taal Source Type: research

The Epidemiology and Management of Pediatric AKI in Asia
Because of the lack of early recognition and referral, the incidence of pediatric acute kidney injury (AKI) in Asia still is underestimated. Although each diagnostic criteria has its own merits, the Kidney Disease Improving Global Outcomes classification now is widely accepted. In Asia, the spectrum of pediatric AKI is wide-ranging, from pediatric AKI in highly sophisticated tertiary-care pediatric intensive care units in resource-rich regions due to advanced procedures such as transplantation, cardiac surgery, and other hospital-acquired causes, to primary care preventable causes, such as infectious diseases, snakebite, a...
Source: Seminars in Nephrology - September 1, 2020 Category: Urology & Nephrology Authors: Ruochen Che, Mohammed Mazheruddin Quadri, Aihua Zhang Source Type: research

Response to Commentary re ‘Barriers in transitioning urologic patients from pediatric to adult care’
As a physician, it is important to accept the limitations of our practice environments and provide optimal care to our patients within these practice environments. While the division of care between pediatric and adult health systems has led to unintended problems surrounding care transition, it has also allowed for specialists to provide better care to both pediatric and adult patients.
Source: Journal of Pediatric Urology - January 27, 2021 Category: Urology & Nephrology Authors: Joshua D. Roth, Wietse Claeys, Piet Hoebeke Tags: Letter to the Editor Source Type: research