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Total 141452 results found since Jan 2013.

Lung transplant curriculum in pulmonary/critical care fellowship training.
Conclusions: A structured educational lung transplant curriculum was associated with improved performance on the pulmonary ITE and was perceived by fellows to be beneficial in their education and training while providing opportunities for fellows to perform transbronchial biopsies. PMID: 23330896 [PubMed - in process]
Source: Teaching and Learning in Medicine - January 1, 2013 Category: Universities & Medical Training Authors: Hayes D, Diaz-Guzman E, Berger R, Hoopes CW Tags: Teach Learn Med Source Type: research

Laboratory tests in liver failure
Publication date: Available online 27 November 2014 Source:Anaesthesia & Intensive Care Medicine Author(s): Frances Lui Laboratory tests of liver function are among most commonly ordered investigations. Interpretation of liver function tests requires analysis of metabolic and synthetic functions of the liver, with some parameters reflecting hepatocellular injury rather than measuring liver function per se. Laboratory liver function tests assist clinical assessment in identification of aetiology of liver failure, serial monitoring of disease progress, classifying severity and scoring systems, predicting deteriorat...
Source: Anaesthesia and intensive care medicine - December 4, 2014 Category: Anesthesiology Source Type: research

The Role and Impact of Extracorporeal Membrane Oxygenation in Critical Care.
Abstract Use of extracorporeal membrane oxygenation (ECMO) has been exponentially increasing over the last decade and is now considered a mainstream lifesaving treatment modality in critical care medicine. However, the need for physician education, training, and experience remains imperative. Although ECMO has traditionally been used in end-stage lung disease and circulatory collapse, it is being adopted for use in right heart failure, as a bridge to heart and lung transplantation, and as rescue therapy for both sepsis and post-organ transplantation. The following article discusses indications, management, complic...
Source: Methodist DeBakey Cardiovascular Journal - April 1, 2018 Category: Cardiology Authors: Ratnani I, Tuazon D, Zainab A, Uddin F Tags: Methodist Debakey Cardiovasc J Source Type: research

Graft-versus-host disease in autologous stem cell transplantation: critical care for critical condition
We thank Chan et al for their interesting article regarding hyperacute rejection. We are really interested in graft-versus-host disease (GVHD) and transplant rejection. We would like to discuss on the clinical manifestations and critical care for this GVHD in autologous stem cell transplantation.
Source: The American Journal of Emergency Medicine - February 11, 2013 Category: Emergency Medicine Authors: Wonngarm Kittanamongkolchai, Narat Srivali, Supawat Ratanapo, Wisit Cheungpasitporn, James M. Leonardo Tags: Correspondence Source Type: research

Impact of Forced Vital Capacity Loss on Survival After the Onset of Chronic Lung Allograft Dysfunction.
Conclusions: At CLAD onset, a subset of patients demonstrating physiology more suggestive of restriction experience worse clinical outcomes. Further study of the biological mechanisms underlying CLAD phenotypes is critical to improving long-term survival after lung transplantation. PMID: 24325429 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - December 10, 2013 Category: Respiratory Medicine Authors: Todd JL, Jain R, Pavlisko EN, Finlen Copeland CA, Reynolds JM, Snyder LD, Palmer SM Tags: Am J Respir Crit Care Med Source Type: research

Hemodynamic Deterioration During Extracorporeal Membrane Oxygenation Weaning in a Patient With a Total Artificial Heart
Conclusion: This interesting scenario highlights the importance for critical care physicians to have an understanding of exact anatomical localization of a total artificial heart, extracorporeal membrane oxygenation, and their potential interactions. In total artificial heart patients with hemodynamic compromise or reduced device filling, consideration should always be given to venous inflow compression, particularly in those with smaller body surface area. Transesophageal echocardiogram is a readily available diagnostic tool that must be considered standard of care, not only in the operating room but also in the ICU, when...
Source: Critical Care Medicine - December 17, 2014 Category: Emergency Medicine Tags: Online Case Report Source Type: research

NOX2 Activation of NKT Cells is Blocked by Adenosine A2A Receptor to Inhibit Lung Reperfusion Injury.
CONCLUSIONS: NOX2 plays a key role in inducing iNKT cell-mediated IL-17 production and subsequent lung injury after ischemia-reperfusion. A primary mechanism for A2AR agonist-mediated protection entails inhibition of NOX2 in iNKT cells. Thus agonism of A2ARs on iNKT cells may be a novel therapeutic strategy to prevent primary graft dysfunction after lung transplantation. PMID: 26757359 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - January 12, 2016 Category: Respiratory Medicine Authors: Sharma AK, LaPar DJ, Stone ML, Zhao Y, Mehta CK, Kron IL, Laubach VE Tags: Am J Respir Crit Care Med Source Type: research

Preoperative risk factors for unexpected postoperative intensive care unit admission: A retrospective case analysis
ConclusionsCHF, acute/chronic kidney injury, PVD and valve disease were significantly associated with increased unexpected ICU admission; patients with CVA suffered increased mortality when admitted to the ICU.
Source: Anaesthesia, Critical Care and Pain Medicine - July 5, 2018 Category: Anesthesiology Source Type: research

ECMO is in the air: Long distance air/ground transport of a child on extra corporeal membrane oxygenation
ConclusionWith an experienced team, and the proper equipment, on-ECMO air transport of critical patients over thousands of kilometers is today safely feasible.
Source: The Egyptian Journal of Critical Care Medicine - December 15, 2018 Category: Intensive Care Source Type: research

The S52F FOXF1 Mutation Inhibits STAT3 Signaling and Causes Alveolar Capillary Dysplasia.
CONCLUSIONS: FOXF1 acts through STAT3 to stimulate neonatal lung angiogenesis. Nanoparticle delivery of STAT3 is a promising strategy to treat ACDMPV associated with decreased STAT3 signaling. PMID: 31199666 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - June 13, 2019 Category: Respiratory Medicine Authors: Pradhan A, Dunn A, Ustiyan V, Bolte C, Wang G, Whitsett JA, Zhang Y, Porollo A, Hu YC, Xiao R, Szafranski P, Shi D, Stankiewicz P, Kalin TV, Kalinichenko VV Tags: Am J Respir Crit Care Med Source Type: research

Risk factors of mortality among patients hospitalised with COVID-19 in a critical care or hospital care unit: analysis of the French national medicoadministrative database
CONCLUSION: This analysis confirms the role of age as the major risk factor of death in patients with COVID-19 irrespective to admission to critical care and therefore supports the current vaccination policies targeting older individuals.PMID:34711641 | DOI:10.1136/bmjresp-2021-001002
Source: Respiratory Care - October 29, 2021 Category: Respiratory Medicine Authors: Eric Ouattara Amelie Bruandet Aur élie Borde Xavier Lenne Florence Binder-Foucard Maggie Le-Bourhis-Zaimi Joris Muller Pierre Tran Ba Loc Fabienne S éguret Sophie Tezenas du Montcel V éronique Gilleron Source Type: research

Critical Care Management of the Lung Transplant Recipient
Lung transplantation is often the only treatment option for patients with severe irreversible lung disease. Improvements in donor and recipient selection, organ allocation, surgical techniques, and immunosuppression have all contributed to better survival outcomes after lung transplantation. Nonetheless, lung transplant recipients still experience frequent complications, often necessitating treatment in an intensive care setting. In addition, the use of extracorporeal life support as a means of bridging critically ill patients to lung transplantation has become more widespread. This review focuses on the critical care aspe...
Source: Clinics in Chest Medicine - February 10, 2023 Category: Respiratory Medicine Authors: Jake G. Natalini, Emily S. Clausen Source Type: research

Lung Transplantation for Cystic FibrosisLung Transplantation for Cystic Fibrosis
Find out more about when to consider lung transplantation and more for patients with cystic fibrosis. Seminars in Respiratory and Critical Care Medicine
Source: Medscape Today Headlines - May 20, 2015 Category: Consumer Health News Tags: Critical Care Journal Article Source Type: news