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< em > In Silico < /em > Investigation of Conserved miRNAs and Their Targets From the Expressed Sequence Tags in < em > Neospora Caninum < /em > Genome
Bioinform Biol Insights. 2021 Dec 6;15:11779322211046729. doi: 10.1177/11779322211046729. eCollection 2021.ABSTRACTNeospora caninum is a protozoan parasite, the etiologic agent of Neosporosis-a common cause of abortion in cattle worldwide. Herd level prevalence of Neosporosis could be as high as 90%. However, there is no approved treatment and vaccines available for Neosporosis. MicroRNA (miRNA) based prophylaxis and therapeutics could be options for Neosporosis in cattle and other animals. The current study aimed to investigate the genome of Neospora caninum to identify and characterize the conserved miRNAs through Expres...
Source: Bioinformatics and Biology Insights - December 13, 2021 Category: Bioinformatics Authors: Moumita Das Mahmudul Hasan Sharmin Akter Sawrab Roy Binayok Sharma Md Shahidur Rahman Chowdhury Md Irtija Ahsan Rubaiat Nazneen Akhand Md Bashir Uddin Syed Sayeem Uddin Ahmed Source Type: research
Identifying environmental factors that influence immune response to SARS-CoV-2: Systematic evidence map protocol
Environ Int. 2022 Apr 8;164:107230. doi: 10.1016/j.envint.2022.107230. Online ahead of print.ABSTRACTBACKGROUND: Widespread environmental contamination can directly interact with human immune system functions. Environmental effects on the immune system may influence human susceptibility to respiratory infections as well as the severity of infectious diseases, such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Furthermore, the efficacy of vaccines to respiratory diseases may be impacted by environmental exposures through immune perturbations. Given the quick pace of research about COVID-19 and associa...
Source: Environment International - April 21, 2022 Category: Environmental Health Authors: Swati D G Rayasam Max T Aung Courtney Cooper Carol Kwiatkowski Dori R Germolec Andrew A Rooney Vickie R Walker Chanese Forte Tracey J Woodruff Nicholas Chartres Source Type: research
He Was Searching For Intersexual Pigs And Ended Up Finding The World's Rarest Dog
Twenty years after beginning his quest to find what’s been called the world’s rarest canine species, James “Mac” McIntyre was vindicated. There on his camera screen were the images he’d been waiting years for. The New Guinea highland wild dog — an animal once feared extinct — was alive and well, his pictures showed.
“I squealed like a girl,” the 62-year-old said earlier this month, speaking from his Florida home. “It was emotionally such a tremendous moment. It was justification for all the work I’ve done.”
How McIntyre ended up finding the New Guinea ...
Source: Science - The Huffington Post - April 24, 2017 Category: Science Source Type: news
Fight Aging! Newsletter, April 2nd 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
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Source: Fight Aging! - April 1, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Hyperimmune immunoglobulin for people with COVID-19
CONCLUSIONS: We included data from five RCTs that evaluated hIVIG compared to standard therapy, with participants with moderate-to-severe disease. As the studies evaluated different preparations (from humans or from various animals) and doses, we could not pool them. hIVIG prepared from humans may have little to no impact on mortality, and clinical improvement and worsening. hIVIG may increase grade 3-4 adverse events. Studies did not evaluate quality of life. RBD-specific polyclonal F(ab´)2 fragments of equine antibodies may reduce mortality and serious adverse events, and may reduce clinical worsening. However, the stud...
Source: Cochrane Database of Systematic Reviews - January 26, 2023 Category: General Medicine Authors: Catherine Kimber Sarah J Valk Khai Li Chai Vanessa Piechotta Claire Iannizzi Ina Monsef Erica M Wood Abigail A Lamikanra David J Roberts Zoe McQuilten Cynthia So-Osman Lise J Estcourt Nicole Skoetz Source Type: research
Current status of vaccines in psychiatry-A narrative review.
DISCUSSION: The therapeutic potential of vaccines in Substance Use Disorders and Alzheimer Dementia was found to be limited in comparison to the results from animal studies. Safety profile of the immunogens and the adjuvants in humans is possibly the most important limitation. No causal association between Measles Mumps Rubella vaccine and Autism was found.
PMID: 29476951 [PubMed - as supplied by publisher]
Source: Asian Journal of Psychiatry - February 26, 2018 Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
