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Specialty: Molecular Biology
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Total 135484 results found since Jan 2013.
"siRNA traffic lights": arabino-configured 2prime or minute-anchors for fluorescent dyes are key for dual color readout in cell imaging
Org. Biomol. Chem., 2018, Advance Article DOI: 10.1039/C8OB00417J, PaperJeannine Steinmeyer, Heidi-Kristin Walter, Mathilde A. Bichelberger, Violetta Schneider, Tomas Kubar, Franziska Ronicke, Bettina Olshausen, Karin Nienhaus, Gerd Ulrich Nienhaus, Ute Schepers, Marcus Elstner, Hans-Achim Wagenknecht The arabino-configured nucleotide anchor improves the red-to-green fluorescence readout by energy transfer. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - March 22, 2018 Category: Molecular Biology Authors: Jeannine Steinmeyer Source Type: research
Corrigendum SiRNA ‑mediated PIAS1 silencing promotes inflammatory response and leads to injury of cerulein‑stimulated pancreatic acinar cells via regulation of the P38MAPK signaling pathway
Int J Mol Med. 2020 Nov 30. doi: 10.3892/ijmm.2020.4803. Online ahead of print.ABSTRACTFollowing the publication of the above article, an interested reader drew to the authors' attention that the data shown in Fig. 2D representing the P53 and Bax data were strikingly similar. After having re‑examined their raw data, the authors have realized that this error arose inadvertently; the data shown for Bax in the original figure were selected incorrectly. In the article, the expression levels of the apoptosis‑regulatory factors P53 and Bax were investigated by western blot analysis and reverse transcription‑quantitative PC...
Source: International Journal of Molecular Medicine - April 26, 2021 Category: Molecular Biology Authors: Ping Chen Liya Huang Yongping Zhang Minmin Qiao Yaozong Yuan Source Type: research
Tissue Analysis of Lung-Targeted Delivery of siRNA and Plasmid DNA
Methods Mol Biol. 2022;2383:547-553. doi: 10.1007/978-1-0716-1752-6_34.ABSTRACTDevelopment of nucleic acid delivery systems requires the use of adequate tissue analysis methods, especially when aiming tissue-targeted drug delivery. In this chapter, a protocol is presented for analyzing a reporter signal from the lung tissue. Because lung is an important target tissue from the clinical point of view, yet represents a challenge from the histological point of view, this protocol can be used in any lung-targeting drug delivery project.PMID:34766312 | DOI:10.1007/978-1-0716-1752-6_34
Source: Mol Biol Cell - November 12, 2021 Category: Molecular Biology Authors: Kaido Kurrikoff Birgit Vunk Ülo Langel Source Type: research
A Dual Therapeutic System Based on Corrole-siRNA Conjugates
Org. Biomol. Chem., 2022, Accepted Manuscript DOI: 10.1039/D1OB02468J, PaperIfrodet Giorgees, Fan Wu, Zhen Shen, Jean-Paul Desaulniers Corrole molecules are a new generation of photosensitizers (PS) due to their ease of tunability for different medical applications. Their ability to initiate cellular death using a wide range of... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - February 5, 2022 Category: Molecular Biology Authors: Ifrodet Giorgees Source Type: research
siRNA modification and delivery for drug development
Trends Mol Med. 2022 Aug 25:S1471-4914(22)00204-0. doi: 10.1016/j.molmed.2022.08.003. Online ahead of print.NO ABSTRACTPMID:36031544 | DOI:10.1016/j.molmed.2022.08.003
Source: Molecular Medicine - August 28, 2022 Category: Molecular Biology Authors: Mengjie Zhang Yuanyu Huang Source Type: research
Correction to: siRNA modification and delivery for drug development: (Trends in Molecular Medicine, 28:10 p:892-893, 2022)
Trends Mol Med. 2022 Oct 12:S1471-4914(22)00234-9. doi: 10.1016/j.molmed.2022.09.003. Online ahead of print.NO ABSTRACTPMID:36243546 | DOI:10.1016/j.molmed.2022.09.003
Source: Molecular Medicine - October 15, 2022 Category: Molecular Biology Authors: Mengjie Zhang Yuanyu Huang Source Type: research
