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Total 335 results found since Jan 2013.
Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Immunosuppressive therapy and oral anticoagulation in kidney transplant recipients: Direct oral anticoagulants versus vitamin-k antagonists
CONCLUSION: DOACs have similar safety and efficacy than AVK among KTRs treated with ISDs. However, careful evaluation of potential drug interaction and ISDs serum levels is needed.PMID:37573220 | DOI:10.1016/j.ejim.2023.08.003
Source: European Journal of Internal Medicine - August 12, 2023 Category: Internal Medicine Authors: Francesco Santoro Annalisa Casanova Simona Simone Carlo Alfieri Adele Falcone Andrea Dello Strologo Valeria Grandinetti Marco Busutti Giorgia Comai Tommaso Maria Marvulli Maria Grazia Zippo Giuseppe Castellano Gaetano La Manna Loreto Gesualdo Grandaliano Source Type: research
Fight Aging! Newsletter, June 12th 2023
In this study, we investigated the effect of NXP032 on neurovascular stabilization through the changes of PECAM-1, PDGFR-β, ZO-1, laminin, and glial cells involved in maintaining the integrity of the blood-brain barrier (BBB) in aged mice. NXP032 was orally administered daily for 8 weeks. Compared to young mice and NXP032-treated mice, 20-month-old mice displayed cognitive impairments in Y-maze and passive avoidance tests. NXP032 treatment contributed to reducing the BBB damage by attenuating the fragmentation of microvessels and reducing PDGFR-β, ZO-1, and laminin expression, thereby mitigating astrocytes and microglia ...
Source: Fight Aging! - June 11, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Rare Case of Benign Transient Hyperphosphatasemia in a Complicated Multiorgan Adult Transplant Patient: Case Report and Literature Review
Conclusions After ruling out all possibilities that may cause elevated ALP, we concluded that this is a rare case of benign transient hyperphosphatasemia in an adult transplant recipient.PMID:37105451 | DOI:10.1016/j.cca.2023.117364
Source: International Journal of Clinical Chemistry - April 27, 2023 Category: Chemistry Authors: Robert Hoyt Fredrick V Plapp Zhan Ye Amitava Dasgupta Source Type: research
Vitamin D and its positive effect on the PTH/vitamin D/calcium-FGF23/klotho/phosphorus axis in kidney transplant recipients
CONCLUSIONS: treatment with cholecalciferol is effective for the normalization of 25(OH)D, with a beneficial effect on calcium-phosphotropic metabolism characterized by a reduction in PTH concentration, without significant changes in calcemia or calciuria, as well as an increase in phosphatemia, without modifications in FGF23 or klotho concentrations.PMID:36926938 | DOI:10.20960/nh.04415
Source: Nutricion Hospitalaria - March 17, 2023 Category: Nutrition Authors: Lourdes Balc ázar-Hernández Leticia Manuel-Apolinar Guadalupe Vargas Ortega Baldomero Gonz ález-Virla Alfredo Adolfo Reza-Albarr án Mar ía Del Carmen Martínez Jiménez Jos é Luis Martínez Ordaz Victoria Mendoza-Zubieta Lourdes Basurto Source Type: research
