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Specialty: Cardiology
Nutrition: Herbs
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Total 273 results found since Jan 2013.
Zhizi-Chuanxiong herb pair alleviates atherosclerosis progression in ApoE < sup > -/- < /sup > mice by promoting the methylation of FGFR3 to inhibit MAPK/ERK-mediated apoptosis
CONCLUSION: Our findings suggest that ZCHP can effectively attenuate AS progression by inhibiting MAPK/ERK signaling-mediated apoptosis via FGFR3 hypermethylation in the promoter region.PMID:37716492 | DOI:10.1016/j.jep.2023.117188
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Yan Zhang Dandan Li Zijun Jia Jun Mei Ya Wang Ying Zhang Qingbing Zhou Fengqin Xu Source Type: research
Network pharmacology and molecular docking to explore the mechanism of Sheng Xue Bao mixture against iron deficiency anemia
Medicine (Baltimore). 2023 Sep 15;102(37):e35012. doi: 10.1097/MD.0000000000035012.ABSTRACTBased on network pharmacology and molecular docking, we investigated the mechanism of action of Sheng Xue Bao mixture (SXBM) in treating iron deficiency anemia (IDA). We screened the HERB and traditional Chinese medicine systems pharmacology database and analysis platform databases to identify the active ingredients and targets of SXBM. The targets associated with "iron deficiency anemia" were collected from GeneCards, TTD, and OMIM databases. A component-target interaction network was constructed using Cytoscape 3.8.2. The protein-p...
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Yun Wang Huang Qinqin Haixia Wang Hongxu Zhang Xinhua Zhang Weiguo Liu Zhenhua Xiang Yuming Gu Source Type: research
Sitosterol-rich < em > Digera muricata < /em > against 7-ketocholesterol and lipopolysaccharide-mediated atherogenic responses by modulating NF- ΚB/iNOS signalling pathway in macrophages
This study aimed to elucidate the effect of a phytosterol-rich extract of D. muricata on 7-ketocholesterol-mediated atherosclerosis in macrophages. The extract was examined by phytochemical analyses, GC-MS, TLC, DPPH scavenging and hRBC membrane stabilization assays. Macrophage polarization was studied with experimental groups framed based on alamar blue cell viability and griess assays. Regulations of arginase enzyme activity, ROS generation, mitochondrial membrane potential, cell membrane integrity, pinocytosis, lipid uptake and peroxidation, as well as, intracellular calcium deposition were determined. In addition, expr...
Source: Atherosclerosis - September 6, 2023 Category: Cardiology Authors: Sangeetha Ravi Parimalanandhini Duraisamy Mahalakshmi Krishnan Livya Catherene Martin Beulaja Manikandan Manikandan Ramar Source Type: research
Verbascoside: A neuroprotective phenylethanoid glycosides with anti-depressive properties
CONCLUSIONS: These findings provide strong evidence that verbascoside exerts its antidepressant effects through various pharmacological mechanisms. However, further multicentre clinical case-control and molecularly targeted fishing studies are required to confirm the clinical efficacy of verbascoside and its underlying direct targets.PMID:37657207 | DOI:10.1016/j.phymed.2023.155027
Source: Atherosclerosis - September 1, 2023 Category: Cardiology Authors: Yi Zhao Sijia Wang Jin Pan Ke Ma Source Type: research
A propensity score matched comparison of blood pressure lowering in essential hypertension patients treated with antihypertensive Chinese herbal Medicine: comparing the real-world registry data vs. randomized controlled trial
CONCLUSION: The current comparison demonstrated that SXC monotherapy is at least as effective in real-world settings as within the randomized controlled trial for BP lowering in patients with grade 1 hypertension.PMID:37639695 | DOI:10.1080/10641963.2023.2249269
Source: Clinical and Experimental Hypertension - August 28, 2023 Category: Cardiology Authors: Xinxing Lai Zhenghao Fang Zhenyu Dong Shengxian Wu Xiaohua Zhou Ying Gao Source Type: research
Bioassay-guided isolation in < em > Salvia abrotanoides < /em > Karel. stem based on its anti-fungal and anti-trichomonas activity
CONCLUSION AND IMPLICATIONS: Carnosol as the main component was assayed against Candida, Aspergillus, Rhizopus, and Trichomanas species. The results confirmed its effect on Candida compared to standard drugs.PMID:37593167 | PMC:PMC10427786 | DOI:10.4103/1735-5362.371587
Source: Atherosclerosis - August 18, 2023 Category: Cardiology Authors: Mustafa Ghanadian Rasoul Jahanshahi Afshar Hamed Fakhim Hosseinail Yousefi Adam Matkowski Mohammad Khodadadi Shima Gharibi Source Type: research
Targeting Retinol-Binding Protein 4 (RBP4) in the Management of Cardiometabolic Diseases
Cardiovasc Toxicol. 2023 Aug 16. doi: 10.1007/s12012-023-09803-8. Online ahead of print.ABSTRACTThe ancient use of herbs for the treatment of various human diseases have been documented, with several scientific literatures supporting the use of medicinal plants. There is however a major concern about the phyto-constituents in the plants that performs the healing function and the mechanism by which it works for different ailments are still a research prospect. Cardiometabolic disease (CMD) is no doubt becoming more frequent globally and this is due to poor approach in therapy, contrary effects linked with intensive control,...
Source: Cardiovascular Toxicology - August 16, 2023 Category: Cardiology Authors: Cecilia Oluwamodupe Adesola Oluwaseun Adeleye Source Type: research
