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Total 628 results found since Jan 2013.

Relaxing radial retinal incisions for the treatment of persistent macular holes
CONCLUSION: The results of this limited case series suggest that radial retinal incisions of the rim in persistent macula holes after initial surgery with ILM peeling increase the success rate of macula hole closure and results in a relevant increase in BCVA. However, as the number of eyes included in this series is limited, the results must be confirmed in a study with a larger sample size.PMID:37700600 | DOI:10.1177/11206721231201662
Source: European Journal of Ophthalmology - September 13, 2023 Category: Opthalmology Authors: Camenzind-Zuche Hanna Janeschitz-Kriegl Lucas Hasler Pascal Pr ünte Christian Source Type: research

Understanding and interpreting CNN's decision in optical coherence tomography-based AMD detection
CONCLUSION: Critical analysis reveals that the ONL-ISM is the most contributing layer in determining AMD, followed by Nerve Fiber Layer to Inner Plexiform Layer (NFL-IPL).PMID:37671441 | DOI:10.1177/11206721231199126
Source: European Journal of Ophthalmology - September 6, 2023 Category: Opthalmology Authors: S M Azoad Ahnaf Sajib Saha Shaun Frost G M Atiqur Rahaman Source Type: research

Ocular involvement-An unusual initial presentation of chronic myeloid leukemia: A case report
We describe a case of a 29-year-old male who presented in our ophthalmology out-patient department (OPD) with complaints of painless, diminution of vision, which was sudden in onset in right eye (RE) and loss of vision in left eye (LE) for four and seven days, respectively. There had been a history of loss of weight and appetite for the past 2 months. The visual acuity (VA) recorded was finger counting two meters in RE and perception of light in LE with an inaccurate projection of rays in both eyes (BE). The anterior segment evaluation of both eyes (BE) was normal. Fundus revealed multiple elevated yellow subretinal lesion...
Source: Primary Care - August 31, 2023 Category: Primary Care Authors: Mittali Khurana Anupam Singh Himani Pal Arvind K Gupta Barun Kumar Source Type: research

Epiretinal membrane formation and optic disc vascularisation in type 2A macular telangiectasia (MacTel)
CONCLUSION: In type 2A MacTel eyes, ERM formation and abnormal disc vascularisation are uncommon findings. More histopathologic research is needed to characterise these membranes.PMID:37644815 | DOI:10.1177/11206721231198888
Source: European Journal of Ophthalmology - August 30, 2023 Category: Opthalmology Authors: Ramesh Venkatesh Rubble Mangla Ashit Handa Yash Parmar Rohini Sangoram Jay Chhablani Source Type: research

Metabolic changes and retinal remodeling in Heterozygous CRX mutant cats (CRX < sup > RDY/+ < /sup > )
This study investigated retinal remodeling that occurs as photoreceptors degenerate. CRXRdy/+ cats from 6 weeks to 10 years of age were investigated. In vivo structural changes of retinas were analyzed by fundus examination, confocal scanning laser ophthalmoscopy and spectral domain optical coherence tomography. Histologic analyses including immunohistochemistry for computational molecular phenotyping with macromolecules and small molecules. Affected cats had a cone-led photoreceptor degeneration starting in the area centralis. Initially there was preservation of inner retinal cells such as bipolar, amacrine and horizontal...
Source: Experimental Eye Research - August 25, 2023 Category: Opthalmology Authors: Laurence M Occelli Bryan W Jones Taylor J Cervantes Simon M Petersen-Jones Source Type: research

Predictive value of serum retinol binding protein in severity and complications of acute pancreatitis: a retrospective cohort study
CONCLUSIONS: Serum RBP had predictive value for AP severity, local and systemic complications.PMID:37608609 | DOI:10.1080/00365521.2023.2249570
Source: Atherosclerosis - August 23, 2023 Category: Cardiology Authors: Xiao Han Jianbo Ni Bin Li Jingpiao Bao Rong Wan Guoyong Hu Congying Chen Source Type: research

In Vivo Detection of Retinal Ganglion Cell Stress in Rodents with DARC
Methods Mol Biol. 2023;2708:123-129. doi: 10.1007/978-1-0716-3409-7_13.ABSTRACTDARC (detection of apoptosing retinal cells) uses fluorescently tagged Annexin A5 to identify retinal apoptosis non-invasively in vivo using a confocal laser scanning ophthalmoscope (cSLO). This can provide insights into the presence and progression of disease pathology and the efficacy of neuroprotective intervention. The methods of administration, imaging, and quantification of DARC, including the operation of the cSLO, are described here.PMID:37558966 | DOI:10.1007/978-1-0716-3409-7_13
Source: Mol Biol Cell - August 9, 2023 Category: Molecular Biology Authors: Daniel Hill Soyoung Choi Maria Francesca Cordeiro Source Type: research

Confocal Scanning Laser Ophthalmoscopy to Image Retinal Ganglion Cells in Real-Time
Methods Mol Biol. 2023;2708:115-121. doi: 10.1007/978-1-0716-3409-7_12.ABSTRACTReal-time imaging of retinal ganglion cells (RGCs) provides an opportunity for detailed investigation of retinal development, disease mechanisms, and the evaluation of interventions affecting ocular structures. Here we use a transgenic model to describe a step-by-step protocol for visualizing RGC survival in real-time by using confocal scanning laser ophthalmoscopy (cSLO).PMID:37558965 | DOI:10.1007/978-1-0716-3409-7_12
Source: Mol Biol Cell - August 9, 2023 Category: Molecular Biology Authors: Lili Hao Yuan Liu Xiangxiang Liu Richard K Lee Source Type: research