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Total 1181 results found since Jan 2013.
Genome-wide identification and gene expression analysis of GHMP kinase gene family in banana cv. Rasthali
CONCLUSION: Our findings suggested that MaGHMP kinase1 (MaHSK) and MaGHMP kinase3 (MaGlcAK) could be considered promising candidates for thwarting the abiotic stresses in banana.PMID:37731027 | DOI:10.1007/s11033-023-08743-4
Source: Molecular Biology Reports - September 21, 2023 Category: Molecular Biology Authors: Siddhant Chaturvedi Shahirina Khan Neha Thakur Alka Jangra Siddharth Tiwari Source Type: research
Quantitative Time-Course Analysis of Osmotic and Salt Stress in Arabidopsis thaliana using Short Gradient Multi-CV FAIMSpro BoxCar DIA
Mol Cell Proteomics. 2023 Sep 11:100638. doi: 10.1016/j.mcpro.2023.100638. Online ahead of print.ABSTRACTA major limitation when undertaking quantitative proteomic time-course experimentation is the tradeoff between depth-of-analysis and speed-of-analysis. In high complexity and high dynamic range sample types, such as plant extracts, balance between resolution and time is especially apparent. To address this, we evaluate multiple composition voltage (CV) High Field Asymetric Waveform Ion Mobility Spectrometry (FAIMSpro) settings using the latest label-free single-shot Orbitrap-based DIA acquisition workflows for their abi...
Source: Molecular and Cellular Proteomics : MCP - September 13, 2023 Category: Molecular Biology Authors: M C Rodriguez Gallo Q Li M Talasila R G Uhrig Source Type: research
MARCKS Effector Domain, a reversible lipid ligand, illuminates late stages of membrane fusion
Mol Biol Cell. 2023 Sep 6:mbcE23060228. doi: 10.1091/mbc.E23-06-0228. Online ahead of print.ABSTRACTYeast vacuolar HOPS tethers membranes, catalyzes trans-SNARE assembly between R- and Q-SNAREs, and shepherds SNAREs past early inhibition by Sec17. After partial SNARE zippering, fusion is driven slowly by either completion of SNARE zippering or by Sec17/Sec18, but rapid fusion needs zippering and Sec17/Sec18. Using reconstituted vacuolar fusion, we find that MARCKS Effector Domain (MED) peptide, a lipid ligand, blocks fusion reversibly at a late reaction stage. The MED fusion blockade is overcome by either salt extraction, ...
Source: Mol Biol Cell - September 6, 2023 Category: Molecular Biology Authors: Amy Orr William Wickner Source Type: research
Bifunctionalization of styrene through ring-opening-recombination strategy of phenylpropathiazole salt
Org. Biomol. Chem., 2023, Accepted Manuscript DOI: 10.1039/D3OB01271A, PaperYongbo Fan, Shengting Xu, Xinxin Cai, Zhijing Hou, Tianxiang Chen, Guozhang Fu, Zhongzhi Zhu, Xiuwen Chen By opening the ring of a benzothiazole salt, we provide a sulfur source for the bifunctional reaction of styrene. The ring-opening –recombination reaction of the benzothiazole salt simultaneously constructs new C-S,... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - September 5, 2023 Category: Molecular Biology Authors: Yongbo Fan Source Type: research
Recent advances in electrochemical functionalization using diazonium salts
Org. Biomol. Chem., 2023, Advance Article DOI: 10.1039/D3OB00978E, Review ArticleKrishna Kher, Mukesh Dhaker, Prabhat Kumar Baroliya Arenediazonium salts have gained attention in the scientific community due to numerous synthetic applications. Functionalization of arenediazonium salt using electricity offers sustainable, economic, and environmentally friendly chemical transformations for arylation, halogenation and annulation. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - August 24, 2023 Category: Molecular Biology Authors: Krishna Kher Source Type: research
Effects of kosmotropic, chaotropic, and neutral salts on Candida antarctica B lipase: An analysis of the secondary structure and its hydrolytic activity on triglycerides
Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Aug 15:159380. doi: 10.1016/j.bbalip.2023.159380. Online ahead of print.ABSTRACTThe effects of different concentrations of Hofmeister salts on the hydrolytic activity on triglycerides and the secondary structure of lipase B from Candida antarctica (CALB) were investigated. Structural changes after short- and long-time incubation at high salt concentrations were determined using circular dichroism (CD), fluorescence, and RMSD-RMSF simulations. At 5.2 M NaCl, the hydrolytic activity of CALB on tributyrin (TC4) and trioctanoin (TC8) was enhanced by 1.5 (from 817 ± 3.9 to 1228 Â...
Source: Mol Biol Cell - August 17, 2023 Category: Molecular Biology Authors: Martha Martin Del Campo Osvaldo G ómez-Secundino Rosa M Camacho-Ru Ãz Juan C Mateos D Ãaz Marcelo Muller Santos Jorge A Rodr Ãguez Source Type: research
Genome-wide identification and expression analysis of the trihelix transcription factor family in sesame (Sesamum indicum L.) under abiotic stress
CONCLUSION: These findings establish a foundation for further investigation of the trihelix gene-mediated response to abiotic stress in sesame.PMID:37584845 | DOI:10.1007/s11033-023-08640-w
Source: Molecular Biology Reports - August 16, 2023 Category: Molecular Biology Authors: Yunyan Zhao Junchao Liang Zhiqi Wang Tingxian Yan Xiaowen Yan Wenliang Wei Meiwang Le Jian Sun Source Type: research
Fluorescent α-amino acids via Heck–Matsuda reactions of phenylalanine-derived arenediazonium salts
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Rochelle McGrory, Rebecca Clarke, Olivia Marshall, Andrew Sutherland A Heck –Matsuda cross-coupling reaction of a phenylalanine-derived arenediazonium salt with various alkenes has been used for the preparation of fluorescent unnatural α-amino acids. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - August 15, 2023 Category: Molecular Biology Authors: Rochelle McGrory Source Type: research
Recent advancements in electrochemical functionalization using diazonium salts
Org. Biomol. Chem., 2023, Accepted Manuscript DOI: 10.1039/D3OB00978E, Review ArticleKrishna Kher, Mukesh Dhaker, Prabhat Kumar Baroliya Arene diazonium salt has gained concern in scientist community due to its numerous synthetic applications. In the traditional method of dediazoniation of arenediazonium salts, the requirement of toxic oxidants and... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - August 11, 2023 Category: Molecular Biology Authors: Krishna Kher Source Type: research
Heck-Matsuda reactions of phenylalanine-derived arenediazonium salts
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Rochelle McGrory, Rebecca Clarke, Olivia Marshall, Andrew Sutherland The Heck-Matsuda cross-coupling reaction of arenediazonium salts derived from L-phenylalanine with various alkenes has been developed. A two-step process involving the preparation of a tetrafluoroborate diazonium salt from a 4-aminophenylalanine... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - August 10, 2023 Category: Molecular Biology Authors: Rochelle McGrory Source Type: research
Inhibition of cMYC-MAX transcription factors hetero-dimerization with structurally engineered omoMYC to downregulate oncogenic pathways in renal carcinoma
Comput Biol Med. 2023 Jul 20;164:107257. doi: 10.1016/j.compbiomed.2023.107257. Online ahead of print.ABSTRACTIn the current study, we employed, structural informatics, and molecular simulation-based methods to engineer OmoMyc, a c-Myc dominant negative protein, to design novel mutants that could abrogate the c-MYC-MAX complex in Renal Carcinoma (RC). Among the total 472 mutations, only six mutations A61Q, Q64E, Q64K, N77R, Q64E-N77R, and Q64K-N77R were reported to increase the binding affinity and subjected to subsequent analysis such as protein-protein docking. The docking results revealed that the predicted mutants impr...
Source: Mol Biol Cell - August 1, 2023 Category: Molecular Biology Authors: Wenfeng Li Farah Bano Abbas Khan Dong-Qing Wei Abdulrahman Alshammari Bin Xu Yanjing Wang Source Type: research
