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An application of carbohydrate polymers-based surface-modified gold nanoparticles for improved target delivery to liver cancer therapy - A systemic review
This article provides an update on using carbohydrate-based GNPs in liver cancer treatment, imaging, and drug administration. Selective surface modification of several carbohydrate types and further biological uses of GNPs are focused on.PMID:37714232 | DOI:10.1016/j.ijbiomac.2023.126889
Source: International Journal of Biological Macromolecules - September 15, 2023 Category: Biochemistry Authors: Abdullah R Alzahrani Ibrahim Abdel Aziz Ibrahim Naiyer Shahzad Imran Shahid Ibrahim M Alanazi Alaa Hisham Falemban Mohd Fahami Nur Azlina Source Type: research

Polyporus umbellatus polysaccharide iron-based nanocomposite for synergistic M1 polarization of TAMs and combinational anti-breast cancer therapy
Int J Biol Macromol. 2023 Aug 14:126323. doi: 10.1016/j.ijbiomac.2023.126323. Online ahead of print.ABSTRACTM1 polarization of tumor-associated macrophages (TAMs) is a promising approach to breaking through therapeutic barriers imposed by the immunosuppressive tumor microenvironment (TME). As a clinically-used immunopotentiator for cancer patients after chemotherapies; however, the immunomodulatory mechanism and potential of polyporus polysaccharide (PPS) remains unclear. Here, we present mannose-decorated PPS-loaded superparamagnetic iron-based nanocomposites (Man/PPS-SPIONs) for synergistic M1 polarization of TAMs and co...
Source: International Journal of Biological Macromolecules - August 16, 2023 Category: Biochemistry Authors: Tingting Liu Tao Han Congyan Liu Chang Ge Xi Jiang Yuping Liu Fei Kong Xiangyu Su Jiachen Shi Wenting Su Xiaoqi Li Yan Chen Huangqin Zhang Qiuling Ma Ding Qu Source Type: research

Surface Engineering of Nanoparticles toward Cancer Theranostics
Acc Chem Res. 2023 Jun 14. doi: 10.1021/acs.accounts.3c00122. Online ahead of print.ABSTRACTConspectusDevelopment of multifunctional nanoparticles (NPs) with desired properties is a significant topic in the field of nanotechnology and has been anticipated to revolutionize cancer diagnosis and treatment modalities. The surface character is one of the most important parameters of NPs that can directly affect their in vivo fate, bioavailability, and final theranostic outcomes and thus should be carefully tuned to maximize the diagnosis and treatment effects while minimizing unwanted side effects. Surface engineered NPs have u...
Source: Cell Research - June 14, 2023 Category: Cytology Authors: Pei Huang Changrong Wang Hongzhang Deng Yongfeng Zhou Xiaoyuan Chen Source Type: research

BLAB2CancerKD: a knowledge graph database focusing on the association between lactic acid bacteria and cancer, but beyond
Database (Oxford). 2023 May 23;2023:baad036. doi: 10.1093/database/baad036.ABSTRACTIn a broad sense, lactic acid bacteria (LAB) is a general term for Gram-positive bacteria that can produce lactic acid by utilizing fermentable carbohydrates. It is widely used in essential fields such as industry, agriculture, animal husbandry and medicine. At the same time, LAB are closely related to human health. They can regulate human intestinal flora and improve gastrointestinal function and body immunity. Cancer, a disease in which some cells grow out of control and spread to other body parts, is one of the leading causes of human dea...
Source: Cancer Control - May 23, 2023 Category: Cancer & Oncology Authors: Yi Jing Baiyang Feng Jing Gao Jin Li Ganghui Zhou Zhihong Sun Yufei Wang Source Type: research

Fight Aging! Newsletter, January 9th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - January 8, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Phenotypic Characterization and Identification of Potential L-Asparaginase-Producing Thermohalophilic Bacteria from Wawolesea Hot Spring, North Konawe, Southeast Sulawesi, Indonesia
Conclusion:</b> According to the numeric-phenetic analysis results, the isolates AAT 1.4 and CAT 3.4 belong to the species <i>Bacillus subtilis</i>, while isolate AAT 3.2 belongs to the species <i>Brevibacillus limnophilus</i>.PMID:36591934 | DOI:10.3923/pjbs.2022.1021.1032
Source: Pakistan Journal of Biological Sciences: PJBS - January 2, 2023 Category: Biomedical Science Authors: None Muzuni None Suriana Nur Arfa Yanti None Ardiansyah Source Type: research

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