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Nutrition: Carbohydrates
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Total 19250 results found since Jan 2013.
Protecting-group free synthesis of glycoconjugates displaying dual fungicidal and plant defense-eliciting activities
Bioorg Chem. 2023 Sep 3;141:106829. doi: 10.1016/j.bioorg.2023.106829. Online ahead of print.ABSTRACTA straightforward synthesis of carbohydrate templated isoxazolidines is described, by reaction of unprotected glycosylhydroxylamines (operating as 1,3-dipoles) with methyl acrylate using microwave activation. Rhamno- and erythro-isoxazolidines are recognized by plant cells, resulting in a strong ROS-production as a plant immune response, and exert a high antifungal activity against Botrytis cinerea.PMID:37690319 | DOI:10.1016/j.bioorg.2023.106829
Source: Bioorganic Chemistry - September 10, 2023 Category: Chemistry Authors: Nathan No ël Simon Duchateau Gatien Messire Fabien Massicot Jean-Luc Vasse Sandra Villaume Aziz Aziz St éphan Dorey J érôme Crouzet Jean-Bernard Behr Source Type: research
A biospectroscopic approach toward colorectal cancer diagnosis from bodily fluid samples via ATR-MIR spectroscopy combined with multivariate data analysis
In this study, a biospectroscopic approach was reported for the detection of spectral changes and biomarkers for the diagnosis of colorectal cancer (CC) cases from different bodily fluids (blood plasma, blood serum, saliva and colonoscopy disinfection/wash fluids) by using attenuated total reflection-mid infrared (ATR-MIR) spectroscopy. To recognize the molecular level changes in the spectral characteristics of CC and their healthy/control (CH) groups, different multivariate data analyses (HCA, LDA, PCA and SIMCA) were successfully performed over the data of ATR-MIR spectroscopy. Two hundred specimens were characterized in...
Source: Cancer Control - September 9, 2023 Category: Cancer & Oncology Authors: Fuzuli Tugrul Gonul Akin Geyik Berrin Yalinba ş Kaya Betul Peker Cengiz Sukriye Nihan Karuk Elmas Ibrahim Yilmaz Fatma Nur Arslan Source Type: research
Characteristics of Staphylococcus aureus biofilm matured in tryptic soy broth, low-fat milk, or whole milk samples along with inactivation by 405 nm light combined with folic acid
Food Microbiol. 2023 Dec;116:104350. doi: 10.1016/j.fm.2023.104350. Epub 2023 Aug 6.ABSTRACTIn the present study, the characteristics of Staphylococcus aureus biofilms matured in tryptic soy broth (TSB), low-fat milk, or whole milk samples were identified along with their resistance to 405 nm light with or without folic acid. Phenotypic properties of carbohydrate and protein contents in extracellular polymeric substance (EPS) of S. aureus biofilms matured in different conditions were identified. The carbohydrate content was higher in the biofilm matured in low-fat milk (1.27) than the samples matured in whole milk (0.58) a...
Source: Food Microbiology - September 9, 2023 Category: Food Science Authors: Jae-Ik Lee Sang-Soon Kim Dong-Hyun Kang Source Type: research
The Influence of Ketogenic Diet on Gut Microbiota: Potential Benefits, Risks and Indications
Nutrients. 2023 Aug 22;15(17):3680. doi: 10.3390/nu15173680.ABSTRACTThe ketogenic diet (KD) restricts carbohydrate consumption, leading to an increase in ketone bodies, such as acetoacetate, β-hydroxybutyrate, and acetone, which are utilized as energy substrates. This dietary approach impacts several biochemical processes, resulting in improved clinical management of various disorders, particularly in childhood. However, the exact mechanisms underlying the efficacy of KD remain unclear. Interestingly, KD may also impact the gut microbiota, which plays a pivotal role in metabolism, nutrition, and the development of the imm...
Source: Cancer Control - September 9, 2023 Category: Cancer & Oncology Authors: Andrea Santangelo Antonio Corsello Giulia Carla Immacolata Spolidoro Chiara Maria Trovato Carlo Agostoni Alessandro Orsini Gregorio Paolo Milani Diego Giampietro Peroni Source Type: research
Characteristics of Staphylococcus aureus biofilm matured in tryptic soy broth, low-fat milk, or whole milk samples along with inactivation by 405 nm light combined with folic acid
Food Microbiol. 2023 Dec;116:104350. doi: 10.1016/j.fm.2023.104350. Epub 2023 Aug 6.ABSTRACTIn the present study, the characteristics of Staphylococcus aureus biofilms matured in tryptic soy broth (TSB), low-fat milk, or whole milk samples were identified along with their resistance to 405 nm light with or without folic acid. Phenotypic properties of carbohydrate and protein contents in extracellular polymeric substance (EPS) of S. aureus biofilms matured in different conditions were identified. The carbohydrate content was higher in the biofilm matured in low-fat milk (1.27) than the samples matured in whole milk (0.58) a...
Source: Food Microbiology - September 9, 2023 Category: Food Science Authors: Jae-Ik Lee Sang-Soon Kim Dong-Hyun Kang Source Type: research
Preparation, structural characterization, bioactivities, and applications of Crataegus spp. polysaccharides: A review
Int J Biol Macromol. 2023 Sep 7:126671. doi: 10.1016/j.ijbiomac.2023.126671. Online ahead of print.ABSTRACTCrataegus, is a genus within the Rosaceae family. It is recognized as a valuable plant with both medicinal and edible qualities, earning it the epithet of the "nutritious fruit" owing to its abundant bioactive compounds. Polysaccharides are carbohydrate polymers linked by glycosidic bonds, one of the crucial bioactive ingredients of Crataegus spp. Recently, Crataegus spp. polysaccharides (CPs) have garnered considerable attention due to their diverse range of bioactivities, including prebiotic, hypolipidemic, anticanc...
Source: International Journal of Biological Macromolecules - September 9, 2023 Category: Biochemistry Authors: Lei Cheng Qiuli Yang Chaohai Li Jiamei Zheng Yaping Wang Baozhong Duan Source Type: research
N-methyl-O-benzylhydroxylamine derivatives of sialylated oligosaccharides, their synthesis and separation with reversed-phase HPLC
Carbohydr Res. 2023 Sep 3;533:108939. doi: 10.1016/j.carres.2023.108939. Online ahead of print.ABSTRACTThe human milk trisaccharide 3'- sialyllactose was reacted with an excess of N-methyl-O-benzylhydroxylamine (MBHA) and the product 3'- sialyllactose-MBHA was isolated in high (91%) yield by solid-phase extraction. The isomeric trisaccharide 6'-sialyllactose-MBHA was also prepared, in this case by enzymatic sialylation of lactose-MBHA. A 50/50 mixture of the two sialyllactose-MBHA derivatives was easily separated by reversed-phase HPLC. The free oligosaccharides were recovered from their respective MBHA derivatives by acid...
Source: Carbohydrate Research - September 8, 2023 Category: Genetics & Stem Cells Authors: Thomas Norberg Elisabet Kallin Source Type: research
Lactose-Functionalized Carbosilane Glycodendrimers Are Highly Potent Multivalent Ligands for Galectin-9 Binding: Increased Glycan Affinity to Galectins Correlates with Aggregation Behavior
Biomacromolecules. 2023 Sep 8. doi: 10.1021/acs.biomac.3c00426. Online ahead of print.ABSTRACTGalectins, the glycan binding proteins, and their respective carbohydrate ligands represent a unique fundamental regulatory network modulating a plethora of biological processes. The advances in galectin-targeted therapy must be based on a deep understanding of the mechanism of ligand-protein recognition. Carbosilane dendrimers, the well-defined and finely tunable nanoscaffolds with low toxicity, are promising for multivalent carbohydrate ligand presentation to target galectin receptors. The study discloses a synthetic method for ...
Source: Biomacromolecules - September 8, 2023 Category: Biochemistry Authors: Monika M üllerová Michaela Hovorkov á T áňa Závodná Lucie Červenková Št Astná Alena Krupkov á Vojt ěch Hamala Kate řina Nováková Jan Topinka Pavla Bojarov á Tom áš Strašák Source Type: research
