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Opioid Induced Hyperalgesia Prevented by Buprenorphine?
“Buprenorphine is a kappa receptor antagonist. For these reasons, buprenorphine might be unique in its ability to treat chronic pain and possibly OIH.” The opioid crisis has been fueled by the use of opioids to treat chronic pain.  Practice patterns have changed, but doctors are still criticized for their roles in the overuse of opioids.  I’ve sat through community ‘heroin forums’ (sometimes on stage) as sheriffs, politicians, and ‘recovered addicts’ firmly pointed fingers at health professionals.  I, meanwhile, kept my finger under the table, but had the thought that some of the people pointing ...
Source: Suboxone Talk Zone - February 5, 2017 Category: Addiction Authors: Jeffrey Junig MD PhD Tags: Acute Pain Buprenorphine Chronic pain Suboxone treatment buprenorphine treats chronic pain chronic pain treatment opioid induced hyperalgesia opioid pain relief pain vs. addiction Source Type: blogs

Only 1 in 4 Adolescent Treatment Facilities Offer Buprenorphine for Opioid Use Disorder
Only a quarter of U.S. residential treatment facilities for adolescents offer buprenorphine, and only 11% offer buprenorphine for ongoing treatment, according to astudy published this week inJAMA. Buprenorphine is the only medication for opioid use disorder approved by the U.S. Food and Drug Administration for use in those aged 16 to 18 years.“Residential treatment facilities provide an opportunity to reach young people with a range of evidence-based supports at a pivotal time in their lives, and it is crucial that buprenorphine is made available as one of those options,” Nora Volkow, M.D., director of the National Ins...
Source: Psychiatr News - June 15, 2023 Category: Psychiatry Tags: adolescents buprenorphine JAMA medication-assisted treatment opioid use disorder secret shopper Source Type: research

Only 1 in 4 Adolescent Treatment Facilities Offers Buprenorphine for Opioid Use Disorder
Only a quarter of U.S. residential treatment facilities for adolescents offer buprenorphine, and only 11% offer buprenorphine for ongoing treatment, according to astudy published this week inJAMA. Buprenorphine is the only medication for opioid use disorder approved by the U.S. Food and Drug Administration for use in those aged 16 to 18 years.“Residential treatment facilities provide an opportunity to reach young people with a range of evidence-based supports at a pivotal time in their lives, and it is crucial that buprenorphine is made available as one of those options,” Nora Volkow, M.D., director of the National Ins...
Source: Psychiatr News - June 15, 2023 Category: Psychiatry Tags: adolescents buprenorphine JAMA medication-assisted treatment opioid use disorder secret shopper Source Type: research

The SEARCH for Diabetes in Youth Study: Rationale, Findings, and Future Directions.
Abstract The SEARCH for Diabetes in Youth (SEARCH) study was initiated in 2000, with funding from the Centers for Disease Control and Prevention and support from the National Institute of Diabetes and Digestive and Kidney Diseases, to address major knowledge gaps in the understanding of childhood diabetes. SEARCH is being conducted at five sites across the U.S. and represents the largest, most diverse study of diabetes among U.S. youth. An active registry of youth diagnosed with diabetes at age <20 years allows the assessment of prevalence (in 2001 and 2009), annual incidence (since 2002), and trends by age, ra...
Source: Diabetes Care - November 25, 2014 Category: Endocrinology Authors: Hamman RF, Bell RA, Dabelea D, D'Agostino RB, Dolan L, Imperatore G, Lawrence JM, Linder B, Marcovina SM, Mayer-Davis EJ, Pihoker C, Rodriguez BL, Saydah S, for the SEARCH for Diabetes in Youth Study Group Tags: Diabetes Care Source Type: research

Sara—the Search and Rescue Dog—and her Game of Fetch
Editor’s note: Jana Sweeny is the American Red Cross’s Director of International Communications. She and her team are traveling around Colombia this week, visiting communities made safer by the Red Cross.   As we walk into the Colombian Red Cross training center in Pereira, a yellow lab comes bouncing up, waving her tail enthusiastically. The ball in her mouth turns out to be a lime and she is ready to play fetch. Because I can never say no to a dog, I begin a game of “fetch the lime” with her. It turns out that Sara isn’t just a fun companion–she is a retired search and rescue dog.  The Colo...
Source: Red Cross Chat - January 24, 2014 Category: Global & Universal Authors: Jenelle Eli Tags: International Preparedness colombia dogs pets Search and Rescue South America Source Type: news

Buprenorphine: A Key Ingredient in the Fight to Solve America's Pain Crisis
"If you do not change direction, you may end up where you are heading." -- Lao Tzu Over the last few weeks, the CDC, the U.S. Department of Health and Human Services (HHS), and the president of the United States have all separately hit the emergency button over the subject of chronic pain treatment and opioid pain killers. Concerns over the rising tide of pain killer addiction, accidental overdose deaths, and a carryover effect causing a steep rise in heroin use have made this a "code blue" emergency for Washington. President Obama has made it clear that addressing the opioid epidemic is now an administration priority, and...
Source: Healthy Living - The Huffington Post - April 5, 2016 Category: Consumer Health News Source Type: news

Mortality risk of opioid substitution therapy with methadone versus buprenorphine: a retrospective cohort study
Publication date: Available online 15 September 2015 Source:The Lancet Psychiatry Author(s): Jo Kimber, Sarah Larney, Matthew Hickman, Deborah Randall, Louisa Degenhardt Background Opioid dependence increases risk of premature mortality. Opioid substitution therapy with methadone or buprenorphine reduces mortality risk, especially for drug-related overdose. Clinical guidelines recommend methadone as the first line of opioid substitution therapy. We aimed to test whether buprenorphine treatment has a lower mortality risk than does methadone treatment by comparing all-cause mortality and drug-related overdose mortalit...
Source: The Lancet Psychiatry - September 16, 2015 Category: Psychiatry Source Type: research

Exploratory Economic Evaluation of Buprenorphine Treatment in Opioid Use Disorder
J Ment Health Policy Econ. 2021 Sep 1;24(3):89-95.ABSTRACTBACKGROUND: Burden of opioid use disorder (OUD) is expressed in economic values or health metrics like Disability Adjusted Life Years (DALYs). Disability Weight (DW), a component of DALYs is estimated using economic methods or psychometric tools. Estimating DW at patient level using psychometric tools is an alternative to non-population specific DW overestimated by economic methods. Providing Medication Assisted Treatment (MAT) using buprenorphine/naloxone film (BUP/NX-F) for OUD is limited by financial constraints.AIM: To estimate the burden of OUD at patient level...
Source: Journal of Mental Health Policy and Economics - September 23, 2021 Category: Psychiatry Authors: Hesham Farouk Elarabi Hamad Al Ghaferi Nael Hasan Amanda J Lee Mansour Shawky Helal Al Kathiri Abuelgasim Elrasheed Samya Al Maamari Tarek A Gawad Doaa Radwan Abdu Adem John Marsden Source Type: research