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Management: National Institutes of Health (NIH)

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PHS 2023-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR R43/R44 Clinical Trial Not Allowed)
Funding Opportunity PA-23-230 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO), issued by the National Institutes of Health (NIH), the Centers for Disease Control and Prevention (CDC), and the Food and Drug Administration (FDA), invites eligible United States small businesses to submit Small Business Innovation Research (SBIR) grant applications. United States small businesses that have the research capabilities and technological expertise to contribute to the R and D mission(s) of the NIH, CDC, and FDA awarding components identified in this NOFO are encouraged to submit SBIR grant ap...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 12, 2023 Category: Research Source Type: funding

Supervisory Bioinformatics Specialist
The National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM), National Institutes of Health (NIH) is seeking a Supervisory Bioinformatics Specialist
Source: NLM General Announcements - July 12, 2023 Category: Databases & Libraries Source Type: news

PHS 2023-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR R43/R44 Clinical Trial Required)
Funding Opportunity PA-23-231 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity Announcement (NOFO), issued by the National Institutes of Health (NIH) and the Centers for Disease Control and Prevention (CDC) invites eligible United States small businesses to submit Small Business Innovation Research (SBIR) grant applications. United States small businesses that have the research capabilities and technological expertise to contribute to the R and D mission(s) of the NIH and CDC awarding components identified in this NOFO are encouraged to submit SBIR grant applications in response to identifie...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 12, 2023 Category: Research Source Type: funding

Y chromosome affects cancer growth
Two studies found factors on the male Y chromosome that lead to aggressive tumor growth.
Source: NIH Research Matters from the National Institutes of Health (NIH) - July 11, 2023 Category: Consumer Health News Source Type: news

Screening newborns for deadly immune disorder saves lives
Newborn screening for severe combined immunodeficiency (SCID) led to prompt treatment before life-threatening infections occurred.
Source: NIH Research Matters from the National Institutes of Health (NIH) - July 11, 2023 Category: Consumer Health News Source Type: news

Annual Sickle Cell Disease Research FY23 (Day 3)
The National Heart, Lung, and Blood Institute (NHLBI) under the National Institutes of Health (NIH) is set to host the 2023 NHLBI Annual Sickle Cell Disease Research Meeting. The 3-day meeting will commence on August 14, 2023, at 9:00 am EDT and will come to a close on Wednesday, August 16 at 5:00 pm. The conference offers a platform for researchers, health care providers, and other stakeholders who are interested in sickle cell disease to discuss ongoing research, new developments in scientific and clinical aspects of sickle cell disease, and progress updates. The meeting will also provide an opportunity for investigators...
Source: Videocast - All Events - July 10, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Research in Context: Progress toward universal vaccines
Recent pandemics have highlighted the need to be prepared for the next emerging disease, whenever it arrives. Researchers are now working to develop universal vaccines against diseases with pandemic potential.
Source: NIH Research Matters from the National Institutes of Health (NIH) - July 10, 2023 Category: Consumer Health News Source Type: news

How football raises the risk for chronic traumatic encephalopathy
The force of blows to the head that football players experienced over their lives better predicted chronic traumatic encephalopathy than the number of concussions.
Source: NIH Research Matters from the National Institutes of Health (NIH) - July 10, 2023 Category: Consumer Health News Source Type: news

Translating Clinical Trial Results to Clinical Practice During a Pandemic
In February 2020, the National Institutes of Health (NIH) launched a public-private partnership, the Adaptive COVID-19 Treatment Trial (ACTT) network, followed in April 2020 by the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) network, to develop a multidisciplinary coordinated research response to COVID-19. These networks achieved remarkable success in completing multiple adaptive randomized clinical trials (RCTs) and identifying effective (and ineffective) treatments for patients with COVID-19. Even as the pandemic enters a new phase, the results reported from these adaptive trials have important r...
Source: JAMA - Journal of the American Medical Association - July 10, 2023 Category: General Medicine Source Type: research

SAEM Response to the National Institute of Health Request for Information: Future Directions in Violence Against Women (VAW) Research
Acad Emerg Med. 2023 Jul 9. doi: 10.1111/acem.14775. Online ahead of print.NO ABSTRACTPMID:37423251 | DOI:10.1111/acem.14775
Source: Accident and Emergency Nursing - July 9, 2023 Category: Emergency Medicine Authors: Kimberly A Stanford Wendy Macias-Konstantopoulos Judith Linden Pooja Agrawal Emma Cortes Rebecca J Barron Hanni Stoklosa Annette M Dekker James Paxton Sarah Knack Willard W Sharp The S A E M Research Committee Source Type: research

Effects of adjuvant berberine therapy on acute ischemic stroke: A meta-analysis
Phytother Res. 2023 Jul 8. doi: 10.1002/ptr.7920. Online ahead of print.ABSTRACTWe conducted a meta-analysis to evaluate the clinical efficacy of berberine (BBR) in treating acute ischemic stroke (AIS), explore its anti-inflammatory effects, and assess its potential applications for AIS patients. We comprehensively searched nine databases from inception until July 1, 2022, to identify clinical trials investigating the use of BBR in treating AIS. We performed statistical analyses using RevMan5.4 software and focused on primary outcomes such as inflammatory markers as well as secondary outcomes including immune system indica...
Source: Atherosclerosis - July 8, 2023 Category: Cardiology Authors: Dan Luo Baili Yu Shoukai Sun Bonan Chen Harsh Vivek Harkare Longlong Wang Jie Pan Bin Huang Yang Song Tianhong Ma Shihua Shi Source Type: research

Researchers find weaker immune response to viral infections in children with mitochondrial disorders
One of the first human studies on how mitochondrial function impacts immune cells to guide future treatments.
Source: National Institutes of Health (NIH) News Releases - July 7, 2023 Category: American Health Source Type: news