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Total 114 results found since Jan 2013.

Fight Aging! Newsletter, November 14th 2022
In this study, we show that TXNIP is vital for the cell fate choice when cells are challenged by various stress signals. Furthermore, prolonged IGF1 treatment leads to the establishment of a premature senescence phenotype characterized by a unique senescence network signature. Combined IGF1/TXNIP-induced premature senescence can be associated with a typical secretory inflammatory phenotype that is mediated by STAT3/IL-1A signaling. Finally, these mechanistic insights might help with the understanding of basic aspects of IGF1-related pathologies in the clinical setting. Investigating the Ability of Type 2 Diabetes...
Source: Fight Aging! - November 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Sustained employment, work disability and work functioning in CKD patients: a cross-sectional survey study
CONCLUSIONS: Employed CKD patients experience difficulties regarding functioning in work requiring adjustment of work or partial work disability. In addition to dialysis patients, stage G3b-G5 patients are vulnerable concerning sustained employment and work functioning.PMID:36315355 | DOI:10.1007/s40620-022-01476-w
Source: Journal of Nephrology - October 31, 2022 Category: Urology & Nephrology Authors: Manna A Alma Sijrike F van der Mei Sandra Brouwer Luuk B Hilbrands Paul J M van der Boog Herma Uiterwijk Femke Waanders Maaike Hengst Ron T Gansevoort Annemieke Visser Source Type: research

Employment Status and Work Functioning among Kidney Transplant Recipients
CONCLUSIONS: Stable employed kidney transplant recipients report to function well at work. In addition, this study shows that self-reported work functioning is higher after successful kidney transplantation compared with before transplantation.CLINICAL TRIAL REGISTRY NAME AND REGISTRATION NUMBER: TransplantLines Biobank and Cohort study, NCT03272841 PODCAST: This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2022_09_26_CJN05560522.mp3.PMID:36162849 | DOI:10.2215/CJN.05560522
Source: Clinical Journal of the American Society of Nephrology : CJASN - September 26, 2022 Category: Urology & Nephrology Authors: Tim J Knobbe Daan Kremer Femke I Abma Coby Annema Stefan P Berger Gerjan J Navis Sijrike F van der Mei Ute B ültmann Annemieke Visser Stephan J L Bakker TransplantLines Investigators Source Type: research

Adherence to Immunosuppressive Medication in Iraqi Kidney Transplant Recipients During the First Year of Transplant. A Single-Center Experience
CONCLUSIONS: There was a high rate of nonadherence among our sample of Iraqi renal transplant recipients in the first year posttransplant. Time after transplant and transplant complications were related to nonadherence. More extensive multicenter studies are needed to define the actual rate of adherence to immune suppression in Iraq.PMID:35384818 | DOI:10.6002/ect.MESOT2021.P44
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 6, 2022 Category: Transplant Surgery Authors: Ala Ali Huda A Al-Taee Mariam S Jasim Source Type: research