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Total 17424 results found since Jan 2013.

HEAL Initiative: Research to Increase Implementation of Substance Use Preventive Services (R61/R33 Clinical Trial Optional)
Funding Opportunity RFA-DA-24-066 from the NIH Guide for Grants and Contracts. The importance of prevention in combatting the opioid crisis is clear identifying and implementing effective strategies to prevent the onset of opioid misuse and use disorder and reducing the need to treat disorders yields positive individual, societal, and financial benefits. In 2020, 9.5 million people aged 12 or older misused opioids in the past year (NSDUH, 2021), suggesting that there are millions of people whose trajectories could have been changed, had they been exposed to an effective prevention strategy. Currently funded HEAL studies a...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 22, 2023 Category: Research Source Type: funding

HEAL Initiative: Research to Increase Implementation of Substance Use Preventive Services (R01 Clinical Trial Optional)
Funding Opportunity RFA-DA-24-067 from the NIH Guide for Grants and Contracts. The importance of prevention in combatting the opioid crisis is clear identifying and implementing effective strategies to prevent the onset of opioid misuse and use disorder and reducing the need to treat disorders yields positive individual, societal, and financial benefits. In 2020, 9.5 million people aged 12 or older misused opioids in the past year (NSDUH, 2021), suggesting that there are millions of people whose trajectories could have been changed, had they been exposed to an effective prevention strategy. Currently funded HEAL studies a...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 22, 2023 Category: Research Source Type: funding

DuckDuckGo founder says Google ’s phone and manufacturing partnerships thwart competition
The founder of the small search engine company DuckDuckGo is testifying against Google in the biggest antitrust trial in a quarter of a century.#google
Source: Reuters: Health - September 21, 2023 Category: Consumer Health News Source Type: news

Countering Mpox Vaccination Disparities in Los Angeles County, California, May-December 2022
Am J Public Health. 2023 Sep 21:e1-e5. doi: 10.2105/AJPH.2023.307409. Online ahead of print.ABSTRACTProviding equitable access to vaccines for individuals at risk for mpox was critical for containing the 2022 mpox outbreak in Los Angeles County, California. Eligible non-Hispanic Black/African American and Latinx individuals had lower vaccine uptake than did non-Hispanic White individuals, despite having higher mpox case rates. Strategies to address disparities in vaccine uptake included using familiar messaging technology to reach individuals at risk for mpox, using partnerships with community-based organizations to raise ...
Source: Am J Public Health - September 21, 2023 Category: International Medicine & Public Health Authors: Auguste Brihn Nava Yeganeh Sonali Kulkarni Olivia Moir Saloniki Madrid Mario Perez Rita Singhal Andrea A Kim Source Type: research

Results of the European Society of Toxicologic Pathology Survey on the Use of Artificial Intelligence in Toxicologic Pathology
Toxicol Pathol. 2023 Jun;51(4):216-224. doi: 10.1177/01926233231182115.ABSTRACTThe European Society of Toxicologic Pathology (ESTP) initiated a survey through its Pathology 2.0 workstream in partnership with sister professional societies in Europe and North America to generate a snapshot of artificial intelligence (AI) usage in the field of toxicologic pathology. In addition to demographic information, some general questions explored AI relative to (1) the current status of adoption across organizations; (2) technical and methodological aspects; (3) perceived business value and finally; and (4) roadblocks and perspectives....
Source: Toxicologic Pathology - September 21, 2023 Category: Pathology Authors: Xavier Palazzi Erio Barale-Thomas Bhupinder Bawa Jonathan Carter Kyathanahalli Janardhan Heike Marxfeld Abraham Nyska Chandrassegar Saravanan Dirk Schaudien Vanessa L Schumacher Robert H Spaet Simone Tangermann Oliver C Turner Enrico Vezzali Source Type: research

Feedback Sought on Cephalopod Care and Use
Cephalopods are aquatic invertebrate animals that include octopuses, squid, cuttlefish, and nautiluses. Earlier this month, we released a Request for Information (NOT-OD-23-176) seeking public input on the humane care and use of laboratory cephalopods at Assured institutions.   The proposed guidance acknowledges the evidence suggesting these animals would benefit from oversight, but also that there are not yet specific care and use standards to allow them to be regulated under the Public Health Service Policy for the Humane Care and Use of Laboratory Animals (PHS Policy). Instead, the U.S. Government Principles p...
Source: NIH Extramural Nexus - September 20, 2023 Category: Research Authors: Mike Lauer Tags: blog Open Mike Animal Welfare Request For Information (RFI) rigor Source Type: funding

A New Strategy for Rejuvenating Primary Healthcare: The Government-Society Partnership Model
J Prim Care Community Health. 2023 Jan-Dec;14:21501319231200763. doi: 10.1177/21501319231200763.ABSTRACTPrimary healthcare systems worldwide are under stress as increased demands during pandemic surges have exposed deficiencies in the system. Primary healthcare centers have significant responsibilities but are often underfunded and understaffed. Recent events, including the COVID-19 pandemic, have highlighted the importance of a strong primary health center network to promote community health and save lives. Most governments have multiple competing financial needs for scarce resources, ultimately limiting the advancement o...
Source: Primary Care - September 20, 2023 Category: Primary Care Authors: Siddarth S Kasi Source Type: research

In vitro oxygen imaging of acellular and cell-loaded beta cell replacement devices
This article aims to establish the protocols and demonstrate a few examples of in vitro oxygen imaging of BAP devices using EPROI. All pO2 measurements were performed using a recently introduced 720 MHz/25 mT preclinical oxygen imager instrument, JIVA-25™. We began by performing pO2 calibration of the biomaterials used in BAPs at 25 mT magnetic field since no such data exist. We compared the EPROI pO2 measurement with a single-point probe for a few selected materials. We also performed trityl OX071 toxicity studies with fibroblasts, as well as insulin-producing cells (beta TC6, MIN6, and human islet cells). Finally, we p...
Source: Cancer Control - September 20, 2023 Category: Cancer & Oncology Authors: Mrignayani Kotecha Longhai Wang Safa Hameed Navin Viswakarma Minglin Ma Cherie Stabler Corinne A Hoesli Boris Epel Source Type: research

A New Strategy for Rejuvenating Primary Healthcare: The Government-Society Partnership Model
J Prim Care Community Health. 2023 Jan-Dec;14:21501319231200763. doi: 10.1177/21501319231200763.ABSTRACTPrimary healthcare systems worldwide are under stress as increased demands during pandemic surges have exposed deficiencies in the system. Primary healthcare centers have significant responsibilities but are often underfunded and understaffed. Recent events, including the COVID-19 pandemic, have highlighted the importance of a strong primary health center network to promote community health and save lives. Most governments have multiple competing financial needs for scarce resources, ultimately limiting the advancement o...
Source: Primary Care - September 20, 2023 Category: Primary Care Authors: Siddarth S Kasi Source Type: research

New insight into the traditional model of the coagulation cascade and its regulation: illustrated review of a three-dimensional view
Res Pract Thromb Haemost. 2023 Aug 7;7(6):102160. doi: 10.1016/j.rpth.2023.102160. eCollection 2023 Aug.ABSTRACTThe coagulation process relies on an intricate network of three-dimensional structural interactions and subtle biological regulations. In the present review, we illustrate the state of the art of the structural biology of the coagulation cascade by surveying the Protein Data Bank and the EBI AlphaFold databases. Investigations performed in the last decade have provided structural information on essentially all players involved in the process. Indeed, the initial characterization of specific and rather canonical d...
Source: Thrombosis and Haemostasis - September 20, 2023 Category: Hematology Authors: Romualdo Troisi Nicole Balasco Ida Autiero Filomena Sica Luigi Vitagliano Source Type: research

NIDA REI: Training a Diverse Data Science Workforce for Addiction Research (R25 Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-24-025 from the NIH Guide for Grants and Contracts. There are many opportunities to leverage the potential of AI/ML to accelerate the pace of biomedical innovation, while prioritizing and addressing health disparities and inequities and mutually beneficial partnerships can be established to increase the participation of underrepresented researchers and communities. It is critical to provide support for meritorious research, strengthen the research environments and collaborations for successful data science projects, and expose undergraduate and/or graduate students in such environments to merito...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 20, 2023 Category: Research Source Type: funding

Research and Innovation Translation Partnerships In Point of Care Technologies Conference and Technology Showcase
The conference will bring together researchers, technology developers, clinicians, and industry partners from all NIBIB Point of Care Technology Network (POCTRN) centers, regulatory administrators, non-government organization (NGO) leaders, and investors network to discuss complementary expertise and resources to accelerate point-of-care and home-based diagnostic technology innovation, validation, and commercialization.For more information go tohttps://www.nibib.nih.gov/news-events/meetings-events/research-and-innovation-translation-partnerships-point-care-technologies-conference-and-technology-showcaseAir date: 11/28/2023 8:00:00 AM
Source: Videocast - All Events - September 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

CalSTRS Adds Venture Partnership to Collaborative Model
The California State Teachers Retirement System has a new partner for its emerging manager program. Invesco, which had been managing the $320 billion pension plan’s emerging manager fund, started to wind down that offering, prompting a year-long search for a new partner. The total mandate — $1.4…#invesco #sapphirepartners #sapphire #robross #collaborativemodel #chrisailman
Source: Reuters: Health - September 15, 2023 Category: Consumer Health News Source Type: news