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Therapy: Cancer Therapy
Nutrition: Nutrition
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Total 349 results found since Jan 2013.
Participation of protein metabolism in cancer progression and its potential targeting for the management of cancer
Amino Acids. 2023 Aug 30. doi: 10.1007/s00726-023-03316-y. Online ahead of print.ABSTRACTCancer malignancies may broadly be described as heterogeneous disorders manifested by uncontrolled cellular growth/division and proliferation. Tumor cells utilize metabolic reprogramming to accomplish the upregulated nutritional requirements for sustaining their uncontrolled growth, proliferation, and survival. Metabolic reprogramming also called altered or dysregulated metabolism undergoes modification in normal metabolic pathways for anabolic precursor's generation that serves to continue biomass formation that sustains the growth, p...
Source: Amino Acids - August 30, 2023 Category: Biochemistry Authors: Dalong Liu Yun Wang Xiaojiang Li Yan Wang Zhiqiang Zhang Zhifeng Wang Xudong Zhang Source Type: research
Trends in Diet and Cancer Research: A Bibliometric and Visualization Analysis
The objective of the bibliometric analysis was to describe trends in peer-reviewed publications on dietary components and cancer and to highlight research gaps. PubMed was queried for manuscripts with diet- and cancer-related keywords and Medical Subject Headings (MeSH) terms. Metadata covering 99,784 publications from 6469 journals were analyzed to identify trends since 1970 on diet topics across 19 tumor types. Publications focused largely on breast, colorectal, and liver cancer, with fewer papers linking diet with other cancers such as brain, gallbladder, or ovarian. With respect to "unhealthy" diets, many publications ...
Source: Cancer Control - August 12, 2023 Category: Cancer & Oncology Authors: Erin D Giles Sarah A Purcell Jessica Olson Alina Vrieling Kelly A Hirko Kary Woodruff Mary C Playdon Gwendolyn A Thomas L Anne Gilmore Heather K Moberly Annie E Newell-Fugate Source Type: research
Dietary interventions and precision nutrition in cancer therapy
Trends Mol Med. 2023 May 10:S1471-4914(23)00074-6. doi: 10.1016/j.molmed.2023.04.004. Online ahead of print.ABSTRACTIn recent years dietary interventions have become a promising tool in cancer treatment and have demonstrated a powerful ability to alter metabolism and tumor growth, development, and therapeutic response. However, because the mechanisms underlying dietary therapeutics are poorly understood, they are frequently ignored as a potential line of treatment for cancer. We discuss the proposed mechanisms behind the anticancer effects of various diets and their development for clinical use. This review aims to provide...
Source: Trends in Molecular Medicine - June 1, 2023 Category: Molecular Biology Authors: Carlos Mart ínez-Garay Nabil Djouder Source Type: research
Vitamin C: From nutrition to oxygen sensing and epigenetics
Redox Biol. 2023 May 27;63:102753. doi: 10.1016/j.redox.2023.102753. Online ahead of print.ABSTRACTVitamin C is unbeatable - at least when it comes to sales. Of all the vitamin preparations, those containing vitamin C sell best. This is surprising because vitamin C deficiency is extremely rare. Nevertheless, there is still controversy about whether the additional intake of vitamin C supplements is essential for our health. In this context, the possible additional benefit is in most cases merely reduced to the known effect as an antioxidant. However, new findings in recent years on the mechanisms of oxygen-sensing and epige...
Source: Cancer Control - June 1, 2023 Category: Cancer & Oncology Authors: Thomas Kietzmann Source Type: research
Exercise interventions for adults with cancer receiving radiation therapy alone
CONCLUSIONS: There is little evidence on the effects of exercise interventions in people with cancer who are receiving RT alone. While all included studies reported benefits for the exercise intervention groups in all assessed outcomes, our analyses did not consistently support this evidence. There was low-certainty evidence that exercise improved fatigue in all three studies. Regarding physical performance, our analysis showed very low-certainty evidence of a difference favouring exercise in two studies, and very low-certainty evidence of no difference in one study. We found very low-certainty evidence of little or no dif...
Source: Cochrane Database of Systematic Reviews - March 13, 2023 Category: General Medicine Authors: Maike Trommer Simone Marnitz Nicole Skoetz Ronja Rupp Timo Niels Janis Morgenthaler Sebastian Theurich Michael von Bergwelt-Baildon Christian Baues Freerk T Baumann Source Type: research
Impact of Dietary Counseling on Health-Related Quality of Life in Patients with Cancer Awaiting Hepato-Pancreato-Biliary Surgery
We examined the effectiveness of dietary counseling performed within a trimodal prehabilitation study for patients with cancer awaiting hepato-pancreato-biliary (HPB) surgery. Additionally, we explored relationships between nutritional status and health-related quality of life (HRQoL). The dietary intervention aimed to achieve a protein intake of 1.5 g/kg/day and reduce nutrition-impact symptoms. Patients received dietary counseling 4 weeks prior to surgery (prehabilitation group); the rehabilitation group just before surgery. We used 3-day food journals to calculate protein intake and the abridged Patient-generated Subjec...
Source: Nutrition and Cancer - March 3, 2023 Category: Cancer & Oncology Authors: Popi Kasvis Antonio Vigano Tram Bui Franco Carli Robert D Kilgour Source Type: research
