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Late-Onset Vaccine-Induced Immune Thombotic Thrombocytopenia (VITT) with Cerebral Venous Sinus Thrombosis
A previously healthy 42-year-old woman presented to the emergency department with acute onset fluent aphasia. Further clinical examination was unremarkable. Emergency computed tomography (CT) of the head showed two small intracranial hemorrhages of the left temporal lobe and a hyperdense cerebral sinus. CT venogram confirmed cerebral venous sinus thrombosis (CVST) of the left vein of Labb é and sigmoid and transversal sinus (Fig. 1). As the paramedic reported ChAdOx1 nCOV-19 (AZD1222) vaccination 2 weeks before, vaccine-induced thrombotic thrombocytopenia (VITT) was suspected and the patient was treated with intravenous ...
Source: Journal of Stroke and Cerebrovascular Diseases - January 27, 2022 Category: Neurology Authors: Maruan Saleh, Julian Zimmermann, Nils C. Lehnen, Bernd P ötzsch, Johannes M. Weller Tags: Case Report Source Type: research

Arterial intracranial thrombosis as the first manifestation of vaccine-induced immune thrombotic thrombocytopenia (VITT): a case report
We describe a severe case of vaccine-induced immune thrombotic thrombocytopenia (VITT) after the first dose of the ChAdOx1 nCoV-19 vaccine leading to massive ischemic stroke.MethodsA 42-year-old woman developed acute left hemiparesis (NIHSS 12) 9  days after the first vaccine dose.ResultsThe blood tests revealed low platelets (70 103/ μL) and severe increment of D-dimer (70,745 ng/mL FEU). Brain non-contrast computed tomography and multiphasic CT angiography demonstrated a right middle cerebral artery occlusion. The patient was treated with primary thrombectomy, steroids, immunoglobulin, and fondaparinux. Despite the tr...
Source: Neurological Sciences - January 13, 2022 Category: Neurology Source Type: research

Acute prolonged motor aura resembling ischemic stroke after COVID − 19 vaccination (CoronaVac): the first case report
In this study, we present the first case of stroke mimic after CoronaVac vaccination. After negative imaging studies had been performed repeatedly, we reach a conclusion that stroke is unlikely to be the cause. Presumably, this phenomenon could possibly have abnormal functional imaging study. Therefore, we believed that it might be due to cortical spreading depression, like migraine aura, which we had conducted a literature review.
Source: The Journal of Headache and Pain - August 12, 2021 Category: Neurology Source Type: research