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Validated Risk Score for Predicting 6-Month Mortality in Infective Endocarditis Valvular Heart Disease
Conclusions Six-month mortality after IE is 25% and is predicted by host factors, IE characteristics, and IE complications. Surgery during the index hospitalization is associated with lower mortality but is performed less frequently in the highest risk patients. A simplified risk model may be used to identify specific risk subgroups in IE.
Source: JAHA:Journal of the American Heart Association - April 17, 2016 Category: Cardiology Authors: Park, L. P., Chu, V. H., Peterson, G., Skoutelis, A., Lejko-Zupa, T., Bouza, E., Tattevin, P., Habib, G., Tan, R., Gonzalez, J., Altclas, J., Edathodu, J., Fortes, C. Q., Siciliano, R. F., Pachirat, O., Kanj, S., Wang, A., for the International Collaborat Tags: Clinical Studies, Infectious Endocarditis, Valvular Heart Disease, Mortality/Survival Source Type: research

Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement for Severe Aortic Stenosis in Patients With Chronic Kidney Disease Stages 3b to 5
Conclusions CKD stages 3b to 5 increases the risk of mortality after TAVI and SAVR. In this subset of patients, SAVR was associated with somewhat better early and late survival. The risk of acute kidney injury was higher after SAVR. These findings suggest that CKD stages 3b to 5 does not contraindicate SAVR. Strategies to prevent severe acute kidney injury should be implemented with either SAVR or TAVI.
Source: The Annals of Thoracic Surgery - July 19, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Prolonged Cross-Clamping During Aortic Valve Replacement Is an Independent Predictor of Postoperative Morbidity and Mortality: Analysis of the Japan Cardiovascular Surgery Database
Conclusions Prolonged ACCD offers an independent predictor of postoperative morbidity and mortality after isolated AVR for AS despite recent technologic advances and surgical refinements.
Source: The Annals of Thoracic Surgery - September 10, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Prolonged Cross-Clamping During Aortic Valve Replacement Is an Independent Predictor of Postoperative Morbidity and Mortality: Analysis of the Japan Cardiovascular Surgery Database.
CONCLUSIONS: Prolonged ACCD offers an independent predictor of postoperative morbidity and mortality after isolated AVR for AS despite recent technologic advances and surgical refinements. PMID: 27624296 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - September 9, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Iino K, Miyata H, Motomura N, Watanabe G, Tomita S, Takemura H, Takamoto S Tags: Ann Thorac Surg Source Type: research

Outcomes of Dialysis-Dependent Patients After Cardiac Operations in a Single-Center Experience of 483 Patients
Conclusions Patients with DD CRF undergoing cardiac operations have high perioperative and medium-term mortality, particularly in the presence of combined aortic and mitral valve pathologic conditions, active endocarditis, and poor left ventricular function.
Source: The Annals of Thoracic Surgery - December 6, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Outcomes of Dialysis-Dependent Patients After Cardiac Operations in a Single-Center Experience of 483 Patients.
CONCLUSIONS: Patients with DD CRF undergoing cardiac operations have high perioperative and medium-term mortality, particularly in the presence of combined aortic and mitral valve pathologic conditions, active endocarditis, and poor left ventricular function. PMID: 27938884 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - December 5, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Leontyev S, Davierwala PM, Gaube LM, Röhrig KA, Lehmann S, Holzhey DM, Seeburger J, Noack T, Misfeld M, Mohr FW Tags: Ann Thorac Surg Source Type: research

Transcatheter Aortic Valve Implantation in Nonagenarians
Conclusions: Transcatheter aortic valve implantation can be performed in nonagenarians despite very high preoperative risk scores and substantial multimorbidity, with acceptable outcomes.
Source: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery - November 1, 2016 Category: Cardiovascular & Thoracic Surgery Tags: Original Articles Source Type: research

End ‐stage renal disease and severe aortic stenosis: Does valve replacement improve one‐year outcomes?
ConclusionsPatients with ESRD and severe AS have a similar and higher survival with TAVR or SAVR when compared to BAV at 1‐year. These results may influence patient care decisions favoring valve replacement in AS patients with ESRD. © 2016 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - February 16, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Jose F. Condado, Aneel Maini, Bradley Leshnower, Vinod Thourani, Jessica Forcillo, Chandan Devireddy, Kreton Mavromatis, Eric L. Sarin, James Stewart, Robert Guyton, Amy Simone, Patricia Keegan, Stamatios Lerakis, Peter C. Block, Vasilis Babaliaros Tags: Valvular and Structural Heart Diseases Source Type: research

How Good is EPS at Predicting the Future After TAVR?
Permanent pacemaker (PPM) implantation continues to be a significant complication of transcatheter aortic valve replacement (TAVR), occurring in approximately 12% of patients [1]. While device enhancements of new TAVR valves, better patient selection and operator experience have led to a decrease in paravalvular regurgitation, vascular injury, stroke, and new dialysis requirement, pacemaker implantation appears to be the only complication that is increasing in frequency [1]. As TAVR expands to patients with lower risk, the long-term consequences of pacemaker implantation will likely be amplified.
Source: Cardiovascular Revascularization Medicine - March 24, 2017 Category: Cardiology Authors: Brett A. Oestreich, Santiago Garcia Source Type: research

Abstract 016: Endovascular Management of Major Vascular Access Site Complications During Transcatheter Aortic Valve Implantation (TAVI). Session Title: Poster Session I
Conclusion: Many patients with major vascular complications during TAVI can be treated with a pure endovascular approach. In our small series we observed no difference in concurrent complications when an endovascular repair can be rapidly initiated as compared to a primary surgical approach.
Source: Circulation: Cardiovascular Quality and Outcomes - March 31, 2017 Category: Cardiology Authors: Majeed, M. U., Green, K. D., Fudim, M., Robbins, M. A., Zhao, D. X. Tags: Session Title: Poster Session I Source Type: research

Transcatheter Aortic Valve Implantation Versus Re-do Surgery for Failing Surgical Aortic Bioprosthesis: a Multi-Centre Propensity Score Analysis.
CONCLUSIONS: Patients with aortic bioprosthesis failure treated with either redo-SAVR or TAV-in-SAV have similar 30-day and 1-year clinical outcomes. PMID: 28760721 [PubMed - as supplied by publisher]
Source: EuroIntervention - August 3, 2017 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Comparative outcomes of transcatheter aortic valve replacement in African American and Caucasian patients with severe aortic stenosis
ConclusionsThere was no significant difference in the utilization rates, in‐hospital outcomes, and cost of TAVR between Caucasians and AA patients in contemporary US practice. Further comparative studies of surgical and TAVR in AAs and other racial minorities are warranted.
Source: Catheterization and Cardiovascular Interventions - September 23, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Fahad Alqahtani, Sami Aljohani, Ahmad Almustafa, Mohammed Alhijji, Oluseun Ali, David R. Holmes, Mohamad Alkhouli Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

Association of Chronic Kidney Disease With In-Hospital Outcomes of Transcatheter Aortic Valve Replacement
Conclusions Patients with CKD or ESRD have worse in-hospital outcomes after TAVR. AKI is associated with higher in-hospital mortality in patients undergoing TAVR and the incidence of AKI has not declined over the years.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 16, 2017 Category: Cardiology Authors: Gupta, T., Goel, K., Kolte, D., Khera, S., Villablanca, P. A., Aronow, W. S., Bortnick, A. E., Slovut, D. P., Taub, C. C., Kizer, J. R., Pyo, R. T., Abbott, J. D., Fonarow, G. C., Rihal, C. S., Garcia, M. J., Bhatt, D. L. Tags: Structural Source Type: research

Comparison of Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Chronic Kidney Disease
There are few data comparing outcomes of transcatheter aortic valve implantation (TAVI) vs. surgical aortic valve replacement (SAVR) in patients with chronic kidney disease (CKD). In this retrospective cohort study using the National Inpatient Sample 2011 – 2014, we included a total of 2820 TAVI and 4054 SAVR procedures, representative of 14,039 TAVI and 19,835 SAVR procedures nationally. Co-primary outcomes were in-hospital mortality, acute kidney injury (AKI), dialysis-requiring AKI, and post-operative stroke.
Source: The American Journal of Cardiology - October 31, 2017 Category: Cardiology Authors: Nilay Kumar, Rohan Khera, Neetika Garg, Justin B. Echouffo-Tcheugui, Anand Venkatraman, Ambarish Pandey, Deepak L. Bhatt Source Type: research

Transcatheter or surgical aortic valve replacement in patients with advanced kidney disease: A propensity score –matched analysis
ConclusionsIn patients with advanced kidney disease, SAVR was associated with higher mortality and higher periprocedural complications, as compared with TAVR. Thus, benefits of TAVR could be extended in patients with advanced kidney disease who cannot undergo surgery.
Source: Clinical Cardiology - October 1, 2017 Category: Cardiology Authors: Rajkumar Doshi, Jay Shah, Vaibhav Patel, Varun Jauhar, Perwaiz Meraj Tags: CLINICAL INVESTIGATIONS Source Type: research

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