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Therapy: Cardiac Resynchronization Therapy

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Total 150 results found since Jan 2013.

Prediction of long-term outcome of cardiac resynchronization therapy by acute pressure-volume loop measurements
Conclusion Invasive assessment of acute haemodynamics is a reliable tool to determine individual response to CRT. An acute increase in SW predicts long-term response to CRT with a higher accuracy than an acute increase in dP/dtmax, baseline QRS duration, and degree of LV mechanical dyssynchrony.
Source: European Journal of Heart Failure - February 20, 2013 Category: Cardiology Authors: de Roest, G. J., Allaart, C. P., Kleijn, S. A., Delnoy, P. P. H. M., Wu, L., Hendriks, M. L., Bronzwaer, J. G. F., van Rossum, A. C., de Cock, C. C. Tags: CRT Source Type: research

Abstract 227: Prescribing Warfarin at Discharge for Heart Failure Patients without Atrial Fibrillation Findings from the Get With The Guidelines-Heart Failure Registry Poster Session II
Conclusions: Approximately 1 in 10 HF patients without AF or other documented indications are prescribed warfarin at discharge, and prescription rates vary widely across hospitals. Further research is needed to understand why anticoagulation is prescribed to patients with HF in the absence of documented indications.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Eapen, Z., Grau-Sepulveda, M., Fonarow, G., Heidenreich, P., Peterson, E., Hernandez, A. Tags: Poster Session II Source Type: research

Effect of atrioventricular and ventriculoventricular delay optimization on clinical and echocardiographic outcomes of patients treated with cardiac resynchronization therapy: A meta-analysis
Conclusion: The current literature suggests that routine AV and/or VV delay optimization has a neutral effect on clinical and echocardiographic outcomes based on pooled data from randomized and nonrandomized studies. Standardization of patient selection and optimization timing and method may help to further define the role of CRT device optimization.
Source: American Heart Journal - May 2, 2013 Category: Cardiology Authors: Dominique Auger, Ulas Hoke, Jeroen J. Bax, Eric Boersma, Victoria Delgado Tags: Curriculum in Cardiology Source Type: research

Optimisation of cardiac resynchronization therapy in clinical practice during exercise.
CONCLUSION: A potential increase in SV of 10 % can be achieved using Nexfin for optimisation of AV delay during exercise. A considerable number of patients showed benefit with lengthening of the AV delay during exercise. PMID: 23821492 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - July 3, 2013 Category: Cardiology Authors: Molenaar MM, Oude Velthuis B, Scholten MF, Stevenhagen JY, Wesselink WA, van Opstal JM Tags: Neth Heart J Source Type: research

CHADS2 and CHA2DS2-VASc scores to predict morbidity and mortality in heart failure patients candidates to cardiac resynchronization therapy
Conclusion In CRT-D patients, pre-implant CHA2DS2-VASc score is an independent predictor of major clinical events at 30-month follow-up.
Source: Europace - December 16, 2013 Category: Cardiology Authors: Paoletti Perini, A., Bartolini, S., Pieragnoli, P., Ricciardi, G., Perrotta, L., Valleggi, A., Vergaro, G., Michelotti, F., Boggian, G., Sassone, B., Mascioli, G., Emdin, M., Padeletti, L. Tags: Pacing and resynchronization therapy Source Type: research

Effects of AV-delay optimization on hemodynamic parameters in patients with VDD pacemakers.
CONCLUSION: AV-delay optimization in patients treated with VDD-PMs exhibits immediate beneficial effects on hemodynamic parameters that are sustained for 3 months. PMID: 24652015 [PubMed - as supplied by publisher]
Source: Wiener Klinische Wochenschrift - March 21, 2014 Category: Journals (General) Authors: Krychtiuk KA, Nürnberg M, Volker R, Pachinger L, Jarai R, Freynhofer MK, Wojta J, Huber K, Weiss TW Tags: Wien Klin Wochenschr Source Type: research

Scar tissue–guided left ventricular lead placement for cardiac resynchronization therapy in patients with ischemic cardiomyopathy: An acute pressure-volume loop study
Background: Response to cardiac resynchronization therapy (CRT) is hampered by the extent and location of left ventricular (LV) scar tissue. It is commonly advised to avoid scar tissue while placing the LV lead. However, whether individual patients benefit from this strategy remains unclear.Methods: Thirty-two CRT candidates with ischemic cardiomyopathy were enrolled from 2 successive clinical trials (TBS and E-pot study). Magnetic resonance imaging with late contrast enhancement was performed to assess location, degree and transmurality of LV scar tissue. Patients underwent invasive pressure-volume loop measurements to as...
Source: American Heart Journal - January 16, 2014 Category: Cardiology Authors: Gerben Jan de Roest, LiNa Wu, Carel C. de Cock, Matthijs L. Hendriks, Peter Paul H.M. Delnoy, Albert C. van Rossum, Cornelis P. Allaart Tags: Heart Failure Source Type: research

Cardiac Responses to Left Ventricular Pacing in Hearts with Normal Electrical Conduction: Beneficial Effect of Improved Filling is Counteracted by Dyssynchrony.
In conclusion, pacing of the LV lateral wall increased LVEDV by displacing the septum rightwards, suggesting a mechanism for a favorable effect of CRT in narrow QRS. The pacing, however, induced dyssynchrony and therefore reduced LV systolic function. These observations suggest that detrimental effects should be considered when applying CRT in patients with narrow QRS. PMID: 24906920 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Heart and Circulatory Physiology - June 6, 2014 Category: Physiology Authors: Boe E, Russell K, Remme EW, Gjesdal O, Smiseth OA, Skulstad H Tags: Am J Physiol Heart Circ Physiol Source Type: research

Complex cardiac pacing in the setting of a district general hospital: procedural success and complications
Conclusions In the presence of necessary clinical expertise, complex cardiac devices can be implanted successfully and with a high degree of safety in the setting of a district general hospital.
Source: Heart Asia - June 24, 2014 Category: Cardiology Authors: Rahbi, H., El-din, M., Salloum, M., Shaukat, N., Farooq, M. Tags: Original research Source Type: research

Clinical Feasibility of Exercise‐Based A‐V Interval Optimization for Cardiac Resynchronization: A Pilot Study
ConclusionsDetermining optimized A‐V intervals by CPX is feasible. Proposed mechanisms explaining this finding and long‐term impact require further study.
Source: Pacing and Clinical Electrophysiology : PACE - July 15, 2014 Category: Cardiology Authors: INDRAJIT CHOUDHURI, DEAN MACCARTER, RACHAEL SHAW, STEVE ANDERSON, John St. CYR, IMRAN NIAZI Tags: ORIGINAL ARTICLE Source Type: research

Cardiac responses to left ventricular pacing in hearts with normal electrical conduction: beneficial effect of improved filling is counteracted by dyssynchrony
In conclusion, pacing of the LV lateral wall increased LVEDV by displacing the septum rightward, suggesting a mechanism for a favorable effect of CRT in narrow QRS. The pacing, however, induced dyssynchrony and therefore reduced LV systolic function. These observations suggest that detrimental effects should be considered when applying CRT in patients with narrow QRS.
Source: AJP: Heart and Circulatory Physiology - August 1, 2014 Category: Cardiology Authors: Boe, E., Russell, K., Remme, E. W., Gjesdal, O., Smiseth, O. A., Skulstad, H. Tags: MUSCLE MECHANICS AND VENTRICULAR FUNCTION Source Type: research

The Use of Quadripolar Left Ventricular Leads Improves the Hemodynamic Response to Cardiac Resynchronization Therapy
ConclusionsThe quadripolar LV lead was associated with a better hemodynamic response and higher CRT responder rates when compared with unipolar‐simulated and bipolar LV leads.
Source: Pacing and Clinical Electrophysiology : PACE - December 1, 2014 Category: Cardiology Authors: JOAQUÍN OSCA, PAU ALONSO, ÓSCAR CANO, JUAN MIGUEL SÁNCHEZ, DAVID TEJADA, ANA ANDRÉS, MARÍA JOSÉ SANCHO TELLO, JOSÉ OLAGÜE Tags: ORIGINAL ARTICLE Source Type: research

Cardiac Resynchronization Therapy Acutely Improves Ventricular‐Arterial Coupling by Reducing the Arterial Load: Assessment by Pressure–Volume Loops
ConclusionOur data indicate that switching CRT on induces an immediate reduction in arterial load, conceivably as a consequence of restored autonomic balance.
Source: Pacing and Clinical Electrophysiology : PACE - January 28, 2015 Category: Cardiology Authors: PAOLO PIERAGNOLI, GIOVANNI BATTISTA PEREGO, GIUSEPPE RICCIARDI, STEFANIA SACCHI, MARGHERITA PADELETTI, ANTONIO MICHELUCCI, SERGIO VALSECCHI, LUIGI PADELETTI Tags: ORIGINAL ARTICLE Source Type: research

Abstract 224: No Difference in Complications or Mortality by Implanted Cardioverter Defibrillator Type in Veterans Enrolled in The Outcomes Among Veterans with Implantable Devices (OVID) Registry Session Title: Poster Session II
Conclusions: Unadjusted analyses showed an association between dual chamber ICD and CRT-D devices and risk of non-fatal major events and the composite outcome versus single chamber ICD implantation. This did not persist when adjusted for clinical characteristics and comorbidities, though we are underpowered for small differences. Further study is needed as prior reports may not have adjusted adequately for clinical covariates and lacked validated outcomes.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Schneider, P. M., Pellegrini, C. N., Heidenreich, P., Keung, E., Massie, B. M., Aleong, R. G., Peterson, P. N., Varosy, P. D. Tags: Session Title: Poster Session II Source Type: research

Biotronik launches Itrevia MRI-safe quad CRT-D in Japan
Biotronik said today that it launched its Itrevia MRI-safe quad cardiac resynchronization therapy defibrillator in Japan, part of a Japanese rollout of new devices for 2015. The device is equipped with home monitoring connectivity, as well as compatibility with up to 1.5 tesla MRI machines, the German medical device giant said. “As a producer of superior medical technologies, it is imperative for us to have a presence in the world’s leading technologies market. It also makes sense that the world’s biggest producer of ProMRI technology should have a strong presence in the country where MRI scanning is the...
Source: Mass Device - July 2, 2015 Category: Medical Equipment Authors: Fink Densford Tags: Cardiac Assist Devices Cardiac Implants Cardiovascular Surgical Biotronik Source Type: news