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Specialty: Intensive Care

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Total 559 results found since Jan 2013.

Lethal Heatstroke with Disseminated Intravascular Coagulopathy
We report on a case of severe heat stroke due to extended exposure to the sun in an enclosed glass cabin of an agricultural vehicle. Patient treatment, lab results and complications are reported and we examine the current literature on heat stroke.Heat stroke is a very rare and highly severe condition mostly suffered by vulnerable individuals or individuals exposed to extreme physical strain. Per definition a heat stroke is characterized by neurological deficit (especially loss of consciousness), and a high body temperature. Most important treatment is to lower the body temperature below 40 °C as quickly as possible. The ...
Source: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS - January 12, 2022 Category: Intensive Care Authors: Gerrit U Herpertz Lukas Nykamp Oliver C Radke Source Type: research

Right Ventricular Limitation: A Tale of Two Elastances
Am J Respir Crit Care Med. 2022 Oct 18. doi: 10.1164/rccm.202106-1564SO. Online ahead of print.ABSTRACTRight ventricular (RV) dysfunction is a commonly considered cause of a low cardiac output in critically ill patients. Its management can be difficult and requires an understanding of how the RV limits cardiac output. We explain that RV stroke output is caught between the passive elastance of the RV walls during diastolic filling and the active elastance produced by the RV in systole. These two elastances limit RV filling and stroke volume, and consequently limit left ventricular (LV) stroke volume. We emphasize use of the...
Source: Am J Respir Crit Car... - October 18, 2022 Category: Intensive Care Authors: Sheldon Magder Douglas Slobod Nawaporn Assanangkornchai Source Type: research

Pattern of brain injury in the acute setting of human septic shock
Conclusions: Brain MRI in septic shock patients who developed acute brain dysfunction can reveal leukoencephalopathy and ischemic stroke, which is associated with DIC and increased mortality.
Source: Critical Care - September 18, 2013 Category: Intensive Care Authors: Andrea PolitoFrédéric EischwaldAnne-Laure Le MahoAngelo PolitoEric AzabouDjillali AnnaneFabrice ChrétienRobert StevensRobert CarlierTarek Sharshar Source Type: research

Effects of clinically relevant acute hypercapnic and metabolic acidosis on the cardiovascular system: an experimental porcine study
Conclusions: MAC preferentially affects the pulmonary circulation, whereas HCA affects the pulmonary, systemic and regional circulations. The cardiac contractile function was reduced, but the cardiac output was maintained (MAC), or even increased (HCA). The increased ventricular stroke work per minute revealed an increased work demand placed by acidosis on the heart.
Source: Critical Care - December 30, 2013 Category: Intensive Care Authors: Milan StenglLenka LedvinovaJiri ChvojkaJan BenesDagmar JarkovskaJaromir HolasPatrik SoukupJitka SviglerováMartin Matejovic Source Type: research

Temporally downsampled cerebral CT perfusion image restoration using deep residual learning
ConclusionThe trained model can restore the temporally downsampled 15-pass CTP to 30 passes very well. According to the contrast test, sufficient information cannot be restored with, e.g., simple interpolation method and deep convolutional generative adversarial network, but can be restored with the proposed CNN model. This method can be an optional way to reduce radiation dose during CTP imaging.
Source: International Journal of Computer Assisted Radiology and Surgery - October 30, 2019 Category: Intensive Care Source Type: research

Prognostic impact of sustained new-onset atrial fibrillation in critically ill patients
ConclusionsSustained new-onset AF was time-dependently associated with hospital mortality in ICU patients, albeit with some uncertainty since AF duration longer than 48  h was not independently associated with in-hospital death or stroke.
Source: Intensive Care Medicine - November 3, 2019 Category: Intensive Care Source Type: research

Use of novel oral anticoagulants for patients with atrial fibrillation: Systematic review and clinical implications
Abstract: Atrial fibrillation (AF), a common arrhythmia, increases the risk of ischemic stroke. Stroke and bleeding scores for patients with AF can help to stratify risk and determine the need for antithrombotic therapy, for which warfarin has been the gold standard. Although highly effective, warfarin has several limitations that can lead to its underuse. Data from randomized, Phase III clinical trials of the novel oral anticoagulants, dabigatran, a direct thrombin inhibitor, and rivaroxaban and apixaban, both factor Xa inhibitors, indicate these drugs are at least noninferior to warfarin for the prevention of stroke and ...
Source: Heart and Lung - November 13, 2013 Category: Intensive Care Authors: Nancy M. Albert Tags: Care of Patients with Dysrhythmias Source Type: research

New direct oral oral anticoagulants (DOACs) - indications of DOACs.
Abstract The direct oral anticoagulants (DOACs) were developed because of the urgent therapeutic need due to the deficits of vitamin K antagonist therapy. The predominant indications in internal medicine are the acute treatment and secondary prevention of deep venous thrombosis (DVT) and pulmonary embolism (PE) as well as stroke prevention in patients with atrial fibrillation. For the acute therapy and secondary prevention of DVT/PE the DOACS were non inferior to low-molecular-weight heparin (LMWH) plus vitamin K antagonists at a significantly reduced rate of severe bleeding complications. Only Rivaroxaban is curr...
Source: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS - March 1, 2014 Category: Intensive Care Authors: Darius H Tags: Anasthesiol Intensivmed Notfallmed Schmerzther Source Type: research