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Specialty: Transplant Surgery

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Total 557 results found since Jan 2013.

Atrial fibrillation in dialysis patients: time to abandon warfarin?
Abstract Atrial fibrillation (AF) is a frequent clinical complication in dialysis patients, and warfarin therapy represents the most common approach for reducing the risk of stroke in this population. However, current evidence based on observational studies, offer conflicting results, whereas no randomized controlled trials have been carried out so far. Additionally, many clinicians are wary of the possible role of warfarin as vascular calcification inducer and its potential to increase the high risk of bleeding among patients on dialysis. Ideally the most promising therapy would be based on direct inhibitors of f...
Source: The International Journal of Artificial Organs - April 8, 2016 Category: Transplant Surgery Authors: Brancaccio D, Neri L, Bellocchio F, Barbieri C, Amato C, Mari F, Canaud B, Stuard S Tags: Int J Artif Organs Source Type: research

Utility of the Surgical Apgar Score in Kidney Transplantation: Is it Feasible to Predict ICU Admission, Hospital Readmission, Length of Stay, and Cost in This Patient Population?
Conclusion: The findings of this study suggest that a history of stroke in the recipient may lend to a lower SAS and that a low SAS is associated with ICU admission following transplant, leading to higher hospital costs.
Source: Progress in Transplantation - May 19, 2016 Category: Transplant Surgery Authors: Stoll, W. D., Taber, D. J., Palesch, S. J., Hebbar, L. Tags: Original Articles Source Type: research

The Effect of Impella CP on Cardiopulmonary Physiology During Venoarterial Extracorporeal Membrane Oxygenation Support
Abstract Left ventricle (LV) distension is a complication of venoarterial extracorporeal membrane oxygenation (VA‐ECMO) support. The effects of Impella on the pulmonary circulatory physiology were studied in a single‐center study of six consecutive patients on VA‐ECMO support who had LV unloading with Impella. Right ventricular stroke volume, pulmonary hemodynamics, and partial pressure of end‐tidal CO2 (PETCO2) were measured on echocardiogram, pulmonary artery catheter, and capnography, respectively. The addition of Impella CP increased total blood flow and reduced pulmonary artery wedge pressure. There was a smal...
Source: Artificial Organs - June 1, 2017 Category: Transplant Surgery Authors: Hoong Sern Lim Tags: Main Text Source Type: research

No Country for Old Livers? Examining and Optimizing the Utilization of Elderly Liver Grafts
This article is protected by copyright. All rights reserved.
Source: American Journal of Transplantation - September 1, 2017 Category: Transplant Surgery Authors: K J Halazun, A A Rana, B Fortune, R C Quillan, E C Verna, B Samstein, J V Guarrera, T Kato, A D Griesemer, A Fox, R S Brown, J C Emond Tags: Original Article Source Type: research

4D Flow MRI in 3D Printed Models of Aorta Grafted With a Ventricular Assist Device Allows Detailed Embolic Trajectory Analysis
Embolic stroke remains an important source of morbidity and mortality in heart failure patients treated with Ventricular Assist Devices (VADs). Decreasing the probability of cranial versus descending aortic embolic trajectory by optimizing the VAD outflow graft position and terminal curvature angle could reduce embolic stroke risk. The goal of this study is to investigate particle trajectories released by a VAD into the aorta, and the effect changes in outflow graft insertion site and terminal curve have on those trajectories.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: O. Amili, F. Coletti, R. MacIver Source Type: research

Natural Antibodies and Left Ventricular Assist Device Complications
Left ventricular assist devices (LVAD) are widely used as a bridge to heart transplantation or destination therapy for advanced heart failure. However, hemocompatibility-related complications such as pump thrombosis, stroke and bleeding remain frequent. We previously reported that LVAD implantation is followed by a sharp increase in serum levels of IgG natural antibodies (Nabs) recognizing oxidation-specific epitopes (OSE). Nabs have been implicated in inflammatory reactions related to atherosclerosis, ischemic stroke and primary graft dysfunction following heart transplantation.
Source: The Journal of Heart and Lung Transplantation - March 16, 2019 Category: Transplant Surgery Authors: S.B. See, A. Pinsino, N. Kunimune, D. Onat, E. Hittesdorf, A.R. Garan, V.K. Topkara, N. Yoshifumi, H. Takayama, K. Takeda, P.C. Colombo, G. Wagener, M. Yuzefpolskaya, E. Zorn Tags: 606 Source Type: research

Speaking the Same Language? Assessing Blood Pressure Measurement and Effectiveness in Pediatric VAD Patients
This report describes the methods used to obtain BP and effectiveness of BP control among ACTION members. We also describe the development of a BP clinical decision support (CDS) tool to standardize BP reporting and goals.
Source: The Journal of Heart and Lung Transplantation - March 16, 2019 Category: Transplant Surgery Authors: C. Villa, D. Peng, S. Auerbach, S. Kindel, S. Law, A. Lorts, M. Mehegan, M. O'Connor, M. Ploutz, D. Rosenthal, C. VanderPluym, M. Zinn, D. Sutcliffe Tags: 262 Source Type: research

Peak Left Atrial Appendage Emptying Velocity Remains Reduced in Atrial Fibrillation during Continuous Flow Left Ventricular Assist Device Support
Although regions of stasis such as the left atrial appendage (LAA) may be potential sites of thrombus formation during atrial fibrillation (AF), its thrombotic contribution during high flow mechanical unloading is unknown. Moreover, registry studies only show a mixed association of AF and stroke during continuous flow left ventricular assist device (CF LVAD) support. Since a lower peak Left Atrial Appendage Emptying Velocity (LAAEV) of less than 40 cm/s during AF, mechanistically contributes to thrombosis and stroke in non-CF LVAD populations, we sought to evaluate the LAAEV in CF LVAD patients with and without AF.
Source: The Journal of Heart and Lung Transplantation - March 16, 2019 Category: Transplant Surgery Authors: A. Rahman, E. Tam, L. ZHeng, J. Fontes, S. Forest, S. Vukelic, D. Sims, J. Shin, S. Patel, D.J. Goldstein, U.P. Jorde, O. Saeed Tags: 88 Source Type: research

Anti-Coagulation Management in Pediatric Ventricular Assist Device: A Quality Improvement Target
This report describes baseline AC data from ACTION centers, including agents used and aggregate levels of performance, to inform development of specific interventions.
Source: The Journal of Heart and Lung Transplantation - March 16, 2019 Category: Transplant Surgery Authors: C. VanderPluym, M. O'Connor, A. Lorts, M. Ploutz, D. Peng, S. Law, M. Zinn, R. Niebler, D. Rosenthal, J. Conway, S. Auerbach, D. Sutcliffe, M. Mehegan Tags: 29 Source Type: research

Usefulness of antiplatelet therapy testing in children supported with a ventricular assist device
Stroke is the most recognized complication associated with the Berlin Heart EXCOR ® Pediatric ventricular assist device (VAD).1-3 Thromboelastography with Platelet Mapping® (TEG/PM) has become the most commonly used platelet function test in US children supported with the EXCOR®4 after it was incorporated into the Edmonton Antithrombotic Guideline for the FDA Trial of the EXCO R® (Supplementary File).1 Despite its use, stroke occurred in one-third of children in the EXCOR® trial.1-3 Thus, some clinicians have questioned its validity as a primary means to guide antiplatelet therapy dosing in EXCOR® recipients.
Source: The Journal of Heart and Lung Transplantation - April 2, 2019 Category: Transplant Surgery Authors: Lindsay J. May, Xiaoxi Liu, Tiffany Tesoro, Jaden Yang, Clara Lo, Sharon Chen, Jenna Murray, David N. Rosenthal, Alan D. Michelson, Christopher S. Almond Tags: Research Correspondence Source Type: research

Usefulness of anti-platelet therapy testing in children supported with a ventricular assist device
Stroke is the most recognized complication associated with the Berlin Heart EXCOR pediatric ventricular assist device (VAD).1 –3 Thromboelastography with Platelet Mapping (TEG/PM) has become the most commonly used platelet function test utilized in U.S. children supported with the EXCOR4 after it was incorporated into the Edmonton Antithrombotic Guideline for the U.S. Food and Drug Administration Trial of the EXCOR (refe r to Supplementary Material available online at www.jhltonline.org/).1 Despite its use, stroke occurred in one third of children in the EXCOR trial.
Source: The Journal of Heart and Lung Transplantation - April 2, 2019 Category: Transplant Surgery Authors: Lindsay J. May, Xiaoxi Liu, Tiffany Tesoro, Jaden Yang, Clara Lo, Sharon Chen, Jenna Murray, David N. Rosenthal, Alan D. Michelson, Christopher S. Almond Tags: RESEARCH CORRESPONDENCE Source Type: research

Intraoperative Hemodynamic Parameters and Acute Kidney Injury After Living Donor Liver Transplantation
Conclusions. The elevated baseline CVP, elevated baseline RVEDV after anesthesia induction, and decreased SvO2 during anhepatic phase were associated with postoperative AKI. Prospective trials are required to evaluate whether the optimization of these variables may decrease the risk of AKI after LDLT.
Source: Transplantation - August 29, 2019 Category: Transplant Surgery Tags: Original Clinical Science—Liver Source Type: research

Endovascular therapy for hemodialysis patients with atrial fibrillation and cerebral thromboembolism: A case series.
CONCLUSION: In this series, endovascular therapy showed good results without complications. More cases should be investigated to obtain more evidence of successful endovascular therapy for hemodialysis patients. PMID: 31623507 [PubMed - as supplied by publisher]
Source: The International Journal of Artificial Organs - October 16, 2019 Category: Transplant Surgery Authors: Kamijo M, Hayashi W, Otsuka E, Obata Y, Sahara N, Takemoto K, Sakamoto S, Ueki Y, Nishino T Tags: Int J Artif Organs Source Type: research

Increased Mean Platelet Volume is Associated with Decreased Survival in Patients Supported with Impella
Increased mean platelet volume (MPV) has been associated with elevated risk of stroke and myocardial infarction in the general population and stroke/pump thrombosis in Heartmate II recipients. It has been proposed that contact with foreign surfaces and centrifugation promote prothrombotic states with platelet activation and increased MPV. An association between MPV and outcomes of patients treated with percutaneous short-term circulatory devices has not been investigated.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: M. Harutyunyan, K. Doshi, H. Nazeer, E. Joye, O. Saeed, M. Torosoff, U. Jorde, D. Belov Tags: (1029) Source Type: research

Survival Impact of Bacteremia on Left Ventricular Assist Device Patients Who Have Suffered Strokes
Strokes and infection are two potential complications in patients with left ventricular assist devices (LVADs). The combination of infection and stroke is particularly concerning for LVAD recipients and may be interrelated. We evaluated the impact of concomitant bacteremia in LVAD patients who suffered a stroke.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: A.A. Phancao, S. George, A.M. El Banayosy, N.M. Chelikani, M.C. Corder, D.A. Horstmanshof, J.W. Long Tags: (1253) Source Type: research