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Specialty: General Medicine
Procedure: Coronary Artery Bypass Graft

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Total 102 results found since Jan 2013.

The FREEDOM trial: In appropriate patients with diabetes and multivessel coronary artery disease, CABG beats PCI
The Future Revascularization Evaluation in Patients With Diabetes Mellitus: Optimal Management of Multivessel Disease (FREEDOM) trial (N Engl J Med 2012; 367:2375–2384) was designed to resolve the long-standing debate over the optimal revascularization strategy in patients with diabetes mellitus and multivessel coronary artery disease. At a median follow-up of 3.8 years, the incidence of the primary outcome (a composite of death, myocardial infarction, and stroke) was significantly lower with bypass surgery than with percutaneous intervention.
Source: Cleveland Clinic Journal of Medicine - August 1, 2013 Category: Journals (General) Authors: AGGARWAL, B., GOEL, S. S., SABIK, J. F., SHISHEHBOR, M. H. Tags: Interpreting Key Trials Source Type: research

Electrocardiography series. Diabetes mellitus and heart disease.
Abstract Diabetes mellitus is responsible for diverse cardiovascular complications such as accelerated atherosclerosis, increased plaque burden and diffuse coronary lesions. It is also a major risk factor for myocardial infarction, stroke and peripheral vascular disease. Here, we present two cases. The first patient had subtle changes in the ECGs, with severe coronary artery disease requiring coronary artery bypass grafting, while the second had deep T wave inversion in the ECG and was found to have normal coronary arteries and nonischaemic cardiomyopathy. Although ECG failed to show the severity of the disease, i...
Source: Singapore Medical Journal - July 1, 2013 Category: Journals (General) Authors: Ambhore A, Teo SG, Poh KK Tags: Singapore Med J Source Type: research

Composite versus conventional coronary artery bypass grafting strategy for the anterolateral territory: study protocol for a randomized controlled trial
DiscussionThis non-inferiority trial has the potential to advance the adult cardiac surgery field, given the potential benefits associated with the composite grafting strategy.Trial registration: ClinicalTrials.gov: NCT01585285.
Source: Trials - August 26, 2013 Category: Journals (General) Authors: Ariane DrouinNicolas NoiseuxCarl Chartrand-LefebvreGilles SoulezSamer MansourJan-Alexis TremblayFadi BasileIgnacio PrietoLouis-Mathieu Stevens Source Type: research

The case of the furtive finding: atypical atrial flutter
A patient’s arrhythmia was identified only after an electrocardiogram (ECG) lead was attached directly to an atrial epicardial lead. The 87-year-old man had a history of paroxysmal atrial fibrillation, coronary artery disease, and severe mitral and tricuspid regurgitation and was admitted for corrective cardiac surgery. His history included a cardioembolic stroke 10 months prior to admission, hypertension, and hyperlipidemia. He underwent coronary artery bypass grafting (CABG) to the right coronary artery, bioprosthetic mitral valve replacement, tricuspid annulus repair, and a maze cryoablation or cryomaze procedure.
Source: The American Journal of Medicine - July 31, 2014 Category: Journals (General) Authors: Jeffrey Paulsen, Gagan Singh, Uma Srivatsa, Ezra A. Amsterdam Source Type: research

Impact of remote ischemic preconditioning preceding coronary artery bypass grafting on inducing neuroprotection (RIPCAGE): study protocol for a randomized controlled trial
DiscussionThis trial will aim to assess whether RIPC in patients subjected to surgical myocardial revascularization employing cardiopulmonary bypass initiates a neuroprotective response. Should the results of this trial indicate that RIPC is effective in reducing the incidence of adverse neurological events in patients undergoing coronary artery bypass grafting, it could impact on the current standard of care.Trial registration: ClinicalTrials.gov NCT02177981.
Source: BioMed Central - October 27, 2014 Category: Journals (General) Authors: Hrvoje GasparovicTomislav KopjarMilan RadosAlan AnticevicMarko RadosBranko MalojcicVisnja IvancanTea FabijanicMaja CikesDavor MilicicVladimir GasparovicBojan Biocina Source Type: research

Long-term follow-up results in patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stents: results from a single high-volume PCI centre
Conclusions PCI patients with STEMI had the worst hospital and long-term prognosis. The mortality rate after hospital increased markedly in patients with NSTE-ACS. SESs seem to be more effective than PESs.
Source: BMJ Open - August 11, 2014 Category: Journals (General) Authors: Yao, H.-M., Wan, Y.-D., Zhang, X.-J., Shen, D.-L., Zhang, J.-Y., Li, L., Zhao, L.-S., Sun, T.-W. Tags: Open access, Cardiovascular medicine, Surgery Research Source Type: research

The Case of the Furtive Flutter: Atypical Atrial Flutter
A patient's arrhythmia was identified only after an electrocardiogram (ECG) lead was attached directly to an atrial epicardial lead. The 87-year-old man had a history of paroxysmal atrial fibrillation, coronary artery disease, and severe mitral and tricuspid regurgitation; he was admitted for corrective cardiac surgery. His history included a cardioembolic stroke 10 months prior to admission, hypertension, and hyperlipidemia. He underwent coronary artery bypass grafting (CABG) to the right coronary artery, bioprosthetic mitral valve replacement, tricuspid annulus repair, and a maze cryoablation or cryomaze procedure.
Source: The American Journal of Medicine - July 31, 2014 Category: Journals (General) Authors: Jeffrey Paulsen, Gagan Singh, Uma Srivatsa, Ezra A. Amsterdam Tags: ECG image of the month Source Type: research

Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial
Publication date: Available online 16 March 2015 Source:The Lancet Author(s): Marco Valgimigli , Andrea Gagnor , Paolo Calabró , Enrico Frigoli , Sergio Leonardi , Tiziana Zaro , Paolo Rubartelli , Carlo Briguori , Giuseppe Andò , Alessandra Repetto , Ugo Limbruno , Bernardo Cortese , Paolo Sganzerla , Alessandro Lupi , Mario Galli , Salvatore Colangelo , Salvatore Ierna , Arturo Ausiello , Patrizia Presbitero , Gennaro Sardella , Ferdinando Varbella , Giovanni Esposito , Andrea Santarelli , Simone Tresoldi , Marco Nazzaro , Antonio Zingarelli , Nicoletta de Cesare , Stefano Rigattieri , Paolo Tosi , Cataldo Palmieri ,...
Source: The Lancet - March 17, 2015 Category: Journals (General) Source Type: research

Coronary heart disease in moyamoya disease: are they concomitant or coincidence?
Abstract The purpose of this study was to determine the prevalence and characteristics of symptomatic coronary heart disease (CHD) in patients with moyamoya disease (MMD). This retrospective study evaluated 456 patients who received examination for MMD between 1995 and 2012. We reviewed the patients' medical history and coronary imaging, including conventional coronary angiography and coronary computed tomography angiogram (CTA). Among 456 patients with MMD, 21 (4.6%) patients were found to have symptomatic CHD. Ten patients were treated with coronary artery bypass graft or percutaneous coronary intervention for u...
Source: J Korean Med Sci - April 1, 2015 Category: Journals (General) Authors: Nam TM, Jo KI, Yeon JY, Hong SC, Kim JS Tags: J Korean Med Sci Source Type: research

Depression, anxiety and major adverse cardiovascular and cerebrovascular events in patients following coronary artery bypass graft surgery: a five year longitudinal cohort study
Conclusions: Generalized anxiety disorder was significantly associated with MACCE at follow-up after CABG surgery. The findings encourage further research pertaining to generalized anxiety disorder, and theoretical conceptualizations of depression, general distress and anxiety in persons undergoing CABG surgery.
Source: BioMed Central - May 25, 2015 Category: Journals (General) Authors: Phillip TullyHelen WinefieldRobert BakerJohan DenolletSusanne PedersenGary WittertDeborah Turnbull Source Type: research

Is Early Reperfusion a Good Thing? Optimal Timing of CABG Surgery Postacute Myocardial Infarction.
CONCLUSIONS: Our data demonstrate no statistical difference in mortality or in the factors of morbidity studied between either early or late CABG after AMI. PMID: 26630898 [PubMed - in process]
Source: Southern Medical Journal - December 4, 2015 Category: Journals (General) Tags: South Med J Source Type: research

Clinical characteristics, management and 1-year outcomes of patients with acute coronary syndrome in Iran: the Iranian Project for Assessment of Coronary Events 2 (IPACE2)
Conclusions Our study showed that the composition of Iranian patients with ACS regarding the type of ACS is similar to that in developed European countries and is unlike that in developing countries of the Middle East and Africa. We found that our patients with ACS are treated with high levels of adherence to guideline-recommended in-hospital medications.
Source: BMJ Open - December 15, 2015 Category: Journals (General) Authors: Kassaian, S. E., Masoudkabir, F., Sezavar, H., Mohammadi, M., Pourmoghaddas, A., Kojouri, J., Ghaffari, S., Sanaati, H., Alaeddini, F., Pourmirza, B., Mir, E., on-behalf of the IPACE2 registry investigators Tags: Open access, Cardiovascular medicine, Evidence based practice, Medical management Research Source Type: research

Has the difference in mortality between percutaneous coronary intervention and coronary artery bypass grafting in people with heart disease and diabetes changed over the years? A systematic review and meta-regression
Conclusions The difference in outcome between PCI and CABG in diabetics has not narrowed from the beginning—with balloon angioplasty to current PCI—with the second generation of drug eluting stents. In contrast to the non-diabetics, there is a persistent 30% benefit in all cause mortality favouring CABG in diabetics, and this should be a major factor in treatment recommendation.
Source: BMJ Open - December 30, 2015 Category: Journals (General) Authors: Herbison, P., Wong, C.-K. Tags: Open access, Cardiovascular medicine, Diabetes and Endocrinology Research Source Type: research

Circulating microRNAs indicate cardioprotection by sevoflurane inhalation in patients undergoing off-pump coronary artery bypass surgery.
In conclusion, volatile induction and maintenance with sevoflurane resulted in some extent of cardiac function improvement in patients undergoing OPCAB. Cardioprotection by sevoflurane is suggested by reduced cardiac injury compared with propofol, and indicated by the sensitive biomarkers, circulating miR-499 and miR-208b. PMID: 27284310 [PubMed - as supplied by publisher]
Source: Experimental and Therapeutic Medicine - June 12, 2016 Category: Journals (General) Tags: Exp Ther Med Source Type: research