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Total 37 results found since Jan 2013.

Uncoupling Protein 2 as a pathogenic determinant and therapeutic target in cardiovascular and metabolic diseases
Curr Neuropharmacol. 2021 Apr 20. doi: 10.2174/1570159X19666210421094204. Online ahead of print.ABSTRACTUncoupling protein 2 (UCP2) is a mitochondrial protein that acts as an anion carrier. It is involved in the regulation of several processes including mitochondrial membrane potential, generation of reactive oxygen species within the inner mitochondrial membrane and calcium homeostasis. UCP2 expression can be regulated at different levels: genetic (gene variants), transcriptional [by peroxisome proliferator-activated receptors (PPARs) and microRNAs], and post-translational. Experimental evidence indicates that activation ...
Source: Current Neuropharmacology - April 22, 2021 Category: Drugs & Pharmacology Authors: Rosita Stanzione Maurizio Forte Maria Cotugno Franca Bianchi Simona Marchitti Carla Letizia Busceti Francesco Fornai Speranza Rubattu Source Type: research

Impact of Comorbidities on Lung Cancer Screening Evaluation
CONCLUSION: Patient and procedure-level factors may alter the benefits of lung cancer screening. Data concerning individual risk factors and high-risk complications should therefore be incorporated into diagnostic algorithms to optimize clinical benefit and minimize harm. Further study and validation of the risk factors identified herein are warranted.PMID:35641376 | DOI:10.1016/j.cllc.2022.03.012
Source: Clinical Prostate Cancer - May 31, 2022 Category: Cancer & Oncology Authors: Eric M Robinson Benjamin Y Liu Keith Sigel Chung Yin Juan Wisnivesky Minal S Kale Source Type: research

Outcome after decompressive craniectomy in patients with dominant middle cerebral artery infarction: A preliminary report
Conclusion: Language and motor outcomes after DC in patients with DMCAI are not as dismal as commonly perceived. Perhaps young patients (<50 years) with DMCAI should be treated with the same aggressiveness that non-DMCAI is currently dealt with.
Source: Annals of Indian Academy of Neurology - October 25, 2013 Category: Neurology Authors: Amandeep KumarManish Singh SharmaBhawani Shanker SharmaRohit BhatiaManmohan SinghAjay GargRajinder KumarAshish SuriPoodipedi Sarat ChandraShashank Sharad KaleAshok Kumar Mahapatra Source Type: research

Are there "superfoods" for heart health?
Myth or reality: eating certain superfoods can strengthen the heart and protect against heart attack and stroke? It's mostly just myth and wishful thinking, reports the March 2014 Harvard Heart Letter. There's no question that some foods are rich in nutrients that may help keep arteries clear and the heartbeat stable. It's great to eat them. But what's really important is eating a variety of fresh, unprocessed foods that deliver all of the nutrients needed to keep the heart healthy, not just those in a few so-called superfoods. "It's really about the whole package—the combination of nutrients and micronutrients that ...
Source: New Harvard Health Information - February 27, 2014 Category: Consumer Health News Source Type: news

Fruits And Vegetables May Not Prevent Cancer
BOSTON (CBS) – Who hasn’t heard that eating a lot of fruits and vegetables can help you fend off cancer? Dr. Walter Willett, a leading expert on nutrition and health at the Harvard School of Public Health, says your diet may play less of a role in cancer prevention as originally thought. “As better data have come along,” he says, “the benefits for cancer don’t look nearly as impressive.” And fat doesn’t appear to be as bad as once thought for promoting cancer either. “There had been a strong belief that fat in our diet was the major cause of breast cancer, colon cancer, prostate cancer and oth...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 5, 2014 Category: Consumer Health News Authors: deanreddington Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen Cancer Dr. Mallika Marshall Dr. Walter Willett Fruit Vegetables Source Type: news

Why Having a Happy Vegan Holiday Matters
I love this time of the year because, to me, the holidays really emphasize how important it is to be kind to one another. With every email that ends "Have a Happy Holiday!" I'm reminded that during the rest of the year we often let the busy-ness of our lives overtake our sense of humanity and kindness. At the end of the year we change: Charities report higher donations, we remember the family member or friend we haven't spoken to all year, and we take the time to smile at strangers. This year I would like us to consider extending that kindness to all creatures -- those we share our couches with and those we share the plan...
Source: Healthy Living - The Huffington Post - December 25, 2014 Category: Consumer Health News Source Type: news

Effects of organic extracts and their different fractions of five Bangladeshi plants on in vitro thrombolysis
Conclusions: Our study suggests that thrombolytic activity of T. orientalis, B. monnieri and U. sinuata could be considered as very promising and beneficial for the Bangladeshi traditional medicine. Lower effects of other extracts might suggest the lack of bio-active components and/or insufficient quantities in the extract. In vivo clot dissolving property and active component(s) of T. orientalis and B. monnieri for clot lysis could lead the plants for their therapeutic uses. However, further work will establish whether or not, chloroform soluble phytochemicals from these plants could be incorporated as a thrombolytic agen...
Source: BMC Complementary and Alternative Medicine - April 23, 2015 Category: Complementary Medicine Authors: Talha EmranMd RahmanMir UddinMd RahmanMd UddinRaju DashChadny Layzu Source Type: research

New brain diet 'slows mental decline'
ConclusionThis observational study aimed to investigate the relationship between the MIND diet and its protective properties for mental decline in an older population. The study has several strengths, including the large sample size, long observational period of up to nine years, regular annual assessment of cognitive functions, and comprehensive assessment of diet. However, one of the main limitations is that this type of study cannot show cause and effect – it can only show an association between the diet and slower mental decline. There may be other unmeasured factors that account for the results, such as genetics, ...
Source: NHS News Feed - August 6, 2015 Category: Consumer Health News Tags: Food/diet Neurology Source Type: news

The Best Protein You Can Eat, According To Nutritionists
Protein is the key to keeping cravings at bay, building lean muscle and dropping those last few pounds. But according to a new review published in Applied Physiology, Nutrition and Metabolism, it’s not just how much protein you eat that’s important: It's where you get your protein that also matters. The reason is threefold. First of all, every source of protein -- from chicken to peanuts -- contains a different array of amino acids, the building blocks of protein. Of the 20 various amino acids, nine are “essential,” meaning you can only get them from food. So it’s especiall...
Source: Healthy Living - The Huffington Post - August 16, 2015 Category: Consumer Health News Source Type: news