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Kinematic descriptions of upper limb function using simulated tasks in activities of daily living after stroke
Hum Mov Sci. 2021 Jul 9;79:102834. doi: 10.1016/j.humov.2021.102834. Online ahead of print.ABSTRACTAssessment of upper limb function poststroke is critical for clinical management and determining the efficacy of interventions. We designed a unilateral upper limb task to simulate activities of daily living to examine how chronic stroke survivors manage reaching, grasping and handling skills simultaneously to perform the functional task using kinematic analysis. The aim of the study was to compare the motor strategies for performing a functional task between paretic and nonparetic arms. Sixteen chronic stroke survivors were ...
Source: Human Movement Science - July 12, 2021 Category: Neurology Authors: Yen-Wei Chen Wan-Wen Liao Chia-Ling Chen Ching-Yi Wu Source Type: research
PCSK9 inhibition in patients with acute stroke and symptomatic intracranial atherosclerosis: protocol for a prospective, randomised, open-label, blinded end-point trial with vessel-wall MR imaging
BMJ Open. 2022 Apr 29;12(4):e060068. doi: 10.1136/bmjopen-2021-060068.ABSTRACTINTRODUCTION: Dual antiplatelet therapy and high-intensity statins are the mainstay treatment in patients with acute stage, symptomatic intracranial atherosclerotic stenosis (ICAS). Alirocumab is a monoclonal antibody that can inhibit proprotein convertase subtilisin-kexin type 9 and effectively lower low-density lipoprotein cholesterol levels with less side effects than statins. We hypothesise that alirocumab treatment in addition to statin therapy could stabilise intracranial plaque and reduce arterial stenosis.METHODS AND ANALYSIS: In this pro...
Source: Atherosclerosis - April 29, 2022 Category: Cardiology Authors: Yen-Chu Huang Chia-Hao Chang Yuan-Hsiung Tsai Hsu-Huei Weng Leng-Chieh Lin Jiann-Der Lee Source Type: research
Stroke propensity in the Th3+/ mouse model of β-thalassemia intermedia
Neurobiol Dis. 2022 Jun 23:105802. doi: 10.1016/j.nbd.2022.105802. Online ahead of print.ABSTRACTβ-thalassemia is associated with multiple hematological and cerebrovascular symptoms linked to a hypercoagulable state that has not been fully replicated in animal models for the development of stroke treatments. Herein we compared the physiological properties and responses to transient cerebral hypoxia-ischemia (tHI) between six-month-old wildtype and heterozygous Th3/+ mice, a model of non-transfusion-dependent β-thalassemia intermedia (β-TI). We found that Th3/+ mice developed microcytic anemia, splenomegaly, higher plate...
Source: Neurobiology of Disease - June 26, 2022 Category: Neurology Authors: Yu-Yo Sun Hui-Wen Yao Hong-Ru Chen Ching-Wen Chen Melissa M Kinkaid Chia-Yi Kuan Source Type: research
Does Weekends Effect Exist in Asia? Analysis of Endovascular Thrombectomy for Acute Ischemic Stroke in A Medical Center
Conclusions This study revealed nonworking-hour effects truly exist in patients who received EST. Although delays in door-to-groin puncture times were noticed during nonworking hours, significant differences in neurological functions and mortality were not observed between working and nonworking hours. Nevertheless, methods to improve the process during nonworking hours should be explored in the future.PMID:35894472 | DOI:10.2174/1567202619666220727094020
Source: Current Neurovascular Research - July 27, 2022 Category: Neurology Authors: Chia-Wei Lin Hung-Yu Huang Jeng-Hung Guo Wei-Laing Chen Hong-Mo Shih Hsueh-Ting Chu Charles C N Wang Tai Hsu Source Type: research
Impacts of Sensation, Perception and Motor Abilities of the Ipsilesional Upper Limb on Hand Functions in Unilateral Stroke: Quantifications from Biomechanical and Functional Perspectives
The presence of subtle losses in hand dexterity after stroke impacts the regaining of independence with regard to activities of daily living. Therefore, awareness of ipsilesional upper extremity (UE) function may be of importance when drafting a comprehensive rehabilitation program. However, current hand function tests seem to be unable to identify asymptomatic UE impairments.
Source: PM and R - July 17, 2017 Category: Rehabilitation Authors: Hsiu-Yun Hsu, Chia-Wen Ke, Ta-Shen Kuan, Hsiu-Ching Yang, Ching-Liang Tsai, Li-Chieh Kuo Source Type: research
Impacts of Sensation, Perception, and Motor Abilities of the Ipsilesional Upper Limb on Hand Functions in Unilateral Stroke: Quantifications From Biomechanical and Functional Perspectives
The presence of subtle losses in hand dexterity after stroke affects the regaining of independence with regard to activities of daily living. Therefore, awareness of ipsilesional upper extremity (UE) function may be of importance when developing a comprehensive rehabilitation program. However, current hand function tests seem to be unable to identify asymptomatic UE impairments.
Source: PM and R - July 17, 2017 Category: Rehabilitation Authors: Hsiu-Yun Hsu, Chia-Wen Ke, Ta-Shen Kuan, Hsiu-Ching Yang, Ching-Liang Tsai, Li-Chieh Kuo Tags: Original Research Source Type: research
Potential Predictors of Quality of Life in Patients with Stroke: A Follow-Up Study
This study identifies predictors for quality of life (QOL) 6 months later in patients with stroke.
Source: Archives of Physical Medicine and Rehabilitation - September 24, 2017 Category: Rehabilitation Authors: Tzu-Ling Chang, Chia-Ling Chen, Chia-ying Chong Source Type: research
Effects of action observation therapy and mirror therapy after stroke on rehabilitation outcomes and neural mechanisms by MEG: study protocol for a randomized controlled trial
Loss of upper-extremity motor function is one of the most debilitating deficits following stroke. Two promising treatment approaches, action observation therapy (AOT) and mirror therapy (MT), aim to enhance mo...
Source: Trials - October 4, 2017 Category: General Medicine Authors: Tsai-yu Shih, Ching-yi Wu, Keh-chung Lin, Chia-hsiung Cheng, Yu-wei Hsieh, Chia-ling Chen, Chih-jou Lai and Chih-chi Chen Tags: Study protocol Source Type: research
Development of a Social Functioning Assessment using Computerized Adaptive Testing for Patients with Stroke
To develop a Computerized Adaptive Testing of Social Functioning (Social-CAT) for patients with stroke.
Source: Archives of Physical Medicine and Rehabilitation - October 6, 2017 Category: Rehabilitation Authors: Shih-Chieh Lee, Yi-Jing Huang, Gong-Hong Lin, Yeh-Tai Chou, Chia-Yeh Chou, Ching-Lin Hsieh Source Type: research
Seasonal variation in the risk of ischemic stroke in patients with atrial fibrillation: A nationwide cohort study
Several cardiovascular diseases exhibit seasonal variations, but data about cold temperature and risk of ischemic stroke in patients with atrial fibrillation (AF) are limited.
Source: Heart Rhythm - July 2, 2018 Category: Cardiology Authors: Jo-Nan Liao, Tze-Fan Chao, Chia-Jen Liu, Su-Jung Chen, Chung-Lieh Hung, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Fa-Po Chung, Tzeng-Ji Chen, Gregory Y.H. Lip, Shih-Ann Chen Source Type: research
