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Nutrition: Calcium

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Total 218 results found since Jan 2013.

Comparative effects of antihypertensive drugs on stroke outcome in China
ConclusionThis study suggests that early initiation of calcium channel blockers is associated with improved outcome after stroke. Further randomized studies are warranted to confirm these findings and to delineate differential beneficial effects of antihypertensive therapy in stroke prevention.
Source: International Journal of Stroke - July 1, 2014 Category: Neurology Authors: Emma L. Heeley, Jade W. Wei, Ji‐Guang Wang, Hisatomi Arima, Yining Huang, Lawrence K. S. Wong, Craig S. Anderson, Tags: Research Source Type: research

Relative Contributions of Sympathetic, Cholinergic, and Myogenic Mechanisms to Cerebral Autoregulation Clinical Sciences
Conclusions— Our results suggest that myogenic effects occur outside the active region of autoregulation, whereas neurogenic influences are largely responsible for cerebral blood flow control within it. However, our model of cerebral autoregulation left 38% of the cerebral pressure–flow relationship unexplained, suggesting that there are other physiological mechanisms that contribute to cerebral autoregulation.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Hamner, J. W., Tan, C. O. Tags: Cerebrovascular disease/stroke, Doppler ultrasound, Transcranial Doppler etc., Autonomic, reflex, and neurohumoral control of circulation Clinical Sciences Source Type: research

Voltage Gated Calcium Channels Antibody-Associated Autoimmune Encephalitis (P5.228)
ConclusionThis case demonstrates a correlation between a high titer of VGCC antibodies and autoimmune encephalitis. Our patient's initial improvement with steroids and plasma exchange in the face of a negative CT and PET suggests a primary autoimmune process rather than a paraneoplastic etiology, though we admit that it is premature to rule out remission and we will continue to follow herDisclosure: Dr. Alwaki has nothing to disclose. Dr. Lugo has nothing to disclose. Dr. Goshgarian has nothing to disclose. Dr. Ahmad has nothing to disclose. Dr. Hefzy has nothing to disclose. Dr. Mitsias has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Alwaki, A., Lugo, A., Goshgarian, C., Ahmad, O., Hefzy, H., Mitsias, P. Tags: Aging, Dementia, and Cognitive and Behavioral Neurology: Creutzfeldt-Jakob Disease and Subacute Encephalopathies Source Type: research

Are Carotid Artery Stenosis-Isolated and Carotid Artery-Plus Two Distinct Entities? (P7.172)
CONCLUSIONS: CAS-isolated and CAS-plus appear to be two distinct entities with unique demographic and clinical attributes.Disclosure: Dr. Jani has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Hussain has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Jani, V., Malik, A., Hussain, S., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Carotid Disease Source Type: research

Intakes of Potassium, Magnesium, and Calcium and Risk of Stroke Brief Reports
Conclusions— This study supports an association between high magnesium intake and a reduced stroke risk.
Source: Stroke - March 24, 2014 Category: Neurology Authors: Sluijs, I., Czernichow, S., Beulens, J. W. J., Boer, J. M. A., van der Schouw, Y. T., Verschuren, W. M. M., Grobbee, D. E. Tags: Epidemiology Brief Reports Source Type: research

Recurrent Extracranial Internal Carotid Artery Vasospasm Diagnosed by Serial Magnetic Resonance Angiography and Superselective Transarterial Injection of a Calcium Channel Blocker
In conclusion, we recommend intensive radiologic follow-up at the acute stage and therapeutic catheter angiography when the bilateral lesion is evident because bilateral occlusion of the ICA could lead to a catastrophic condition.
Source: Journal of Stroke and Cerebrovascular Diseases - March 21, 2014 Category: Neurology Authors: Yoshiteru Shimoda, Miki Fujimura, Naoto Kimura, Masayuki Ezura, Hiroshi Uenohara, Teiji Tominaga Tags: Case Reports Source Type: research

The neurology of itch
Research over the past 15 years has helped to clarify the anatomy and physiology of itch, the clinical features of neuropathic itch syndromes and the scientific underpinning of effective treatments. Two itch-sensitive pathways exist: a histamine-stimulated pathway that uses mechanically insensitive C-fibres, and a cowhage-stimulated pathway primarily involving polymodal C-fibres. Interactions with pain continue to be central to explaining various aspects of itch. Certain spinal interneurons (Bhlhb5) inhibit itch pathways within the dorsal horn; they may represent mediators between noxious and pruritic pathways, and allow s...
Source: Brain - February 5, 2014 Category: Neurology Authors: Dhand, A., Aminoff, M. J. Tags: Review Article Source Type: research

N-type calcium channel antibody-mediated paraneoplastic limbic encephalitis: A diagnostic challenge
Conclusion: This case highlights limbic encephalitis as an atypical presentation of neuroendocrine cancer. It also illustrates how treatment of the underlying cancer can reverse limbic encephalitis and Lambert–Eaton myasthenic syndrome in a neuroendocrine carcinoma patient even before the paraneoplastic panel becomes negative.
Source: Journal of the Neurological Sciences - January 27, 2014 Category: Neurology Authors: Carlos Kamiya-Matsuoka, David Blas-Boria, Michelle D. Williams, Pedro Garciarena, Sudhakar Tummala, Ivo W. Tremont-Lukats Tags: Original Articles Source Type: research

Upregulation of ANGPTL4 Messenger RNA and Protein in Severely Calcified Carotid Plaques
Conclusions: In high-calcified plaques, ANGPTL4 might be upregulated for antiangiogenic modulating function together with the downregulation of FGFR2, contributing to the stability of the plaques.
Source: Journal of Stroke and Cerebrovascular Diseases - September 30, 2013 Category: Neurology Authors: Hiroyuki Katano, Kazuo Yamada Tags: Original Articles Source Type: research

Inhibition of Calcium/Calmodulin-Dependent Protein Kinase Kinase {beta} and Calcium/Calmodulin-Dependent Protein Kinase IV Is Detrimental in Cerebral Ischemia Basic Sciences
Conclusions— Our data have established that the CaMKK/CaMK IV pathway is a key endogenous protective mechanism in ischemia. Our results suggest that this pathway serves as an important regulator of blood–brain barrier integrity and transcriptional activation of neuroprotective molecules in stroke.
Source: Stroke - August 26, 2013 Category: Neurology Authors: McCullough, L. D., Tarabishy, S., Liu, L., Benashski, S., Xu, Y., Ribar, T., Means, A., Li, J. Tags: Animal models of human disease Basic Sciences Source Type: research

Mitochondrial Calcium Uniporter Opener Spermine Attenuates the Cerebral Protection of Diazoxide through Apoptosis in Rats
Conclusions: Results in our study suggested that diazoxide improved neurologic deficits, decreased infarct volume in cortex but not in subcortex, and apoptosis in cortex against ischemia/reperfusion injury is mediated by spermine.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Lei Zhang, Xiujuan Gao, Xin Yuan, Huanli Dong, Zongwang Zhang, Shilei Wang Tags: Original Articles Source Type: research

Neurodegeneration after transient brain ischemia in aged mice: Beneficial effects of bilobalide.
In conclusion, aged mice show some differences in their response to transient ischemia when compared with young mice. Bilobalide has prominent neuroprotective properties in mice of all ages. PMID: 23850645 [PubMed - as supplied by publisher]
Source: Brain Research - July 11, 2013 Category: Neurology Authors: Schwarzkopf TM, Koch KA, Klein J Tags: Brain Res Source Type: research

Low Serum Calcium Levels Contribute to Larger Hematoma Volume in Acute Intracerebral Hemorrhage Brief Reports
Conclusions— Low admission serum calcium levels were associated with larger hematoma volume and higher National Institutes of Health Stroke Scale score among patients with acute intracerebral hemorrhage.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Inoue, Y., Miyashita, F., Toyoda, K., Minematsu, K. Tags: Acute Cerebral Hemorrhage Brief Reports Source Type: research

MiRNA-424 Protects Against Permanent Focal Cerebral Ischemia Injury in Mice Involving Suppressing Microglia Activation Basic Sciences
Conclusions— MiR-424 overexpression lessened the ischemic brain injury through suppressing microglia activation by translational depression of key activators of G1/S transition, suggesting a novel miR-based intervention strategy for stroke.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Zhao, H., Wang, J., Gao, L., Wang, R., Liu, X., Gao, Z., Tao, Z., Xu, C., Song, J., Ji, X., Luo, Y. Tags: Acute Cerebral Infarction Basic Sciences Source Type: research

Magnesium treatment for neuroprotection in ischemic diseases of the brain
This article reviews experimental and clinical data on the use of magnesium as a neuroprotective agent in various conditions of cerebral ischemia. Whereas magnesium has shown neuroprotective properties in animal models of global and focal cerebral ischemia, this effect could not be reproduced in a large human stroke trial. These conflicting results may be explained by the timing of treatment. While treatment can be started before or early after ischemia in experimental studies, there is an inevitable delay of treatment in human stroke. Magnesium administration to women at risk for preterm birth has been investigated in sev...
Source: Experimental and Translational Stroke Medicine - April 25, 2013 Category: Neurology Source Type: research