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Management: National Institutes of Health (NIH)

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Total 1650 results found since Jan 2013.

Mechanical thrombectomy in patients with stroke due to large vessel occlusion in the anterior circulation and low baseline NIHSS score
J Integr Neurosci. 2021 Sep 30;20(3):645-650. doi: 10.31083/j.jin2003068.ABSTRACTWe sought to verify the benefit of mechanical thrombectomy in patients with acute ischemic stroke due to large vessel occlusion in the anterior circulation and low National Institute of Health stroke scale score at presentation. The prospective database of our stroke center was screened for patients with acute ischemic stroke due to large vessel occlusion and a baseline National Institute of Health stroke scale score ≤5 that had undergone mechanical thrombectomy. Outcome measures were the modified Rankin Scale (mRS) score at 90 days, brain b...
Source: Journal of Integrative Neuroscience - October 14, 2021 Category: Neuroscience Authors: Andrea M Alexandre Iacopo Valente Giovanni Frisullo Roberta Morosetti Danilo Genovese Andrea Bartolo Riccardo Gigli Claudia Rollo Luca Scarcia Francesca Carosi Giusy Fortunato Francesco D'Argento Paolo Calabresi Giacomo Della Marca Alessandro Pedicelli Al Source Type: research

Acute Stroke Diagnosis
Am Fam Physician. 2022 Jun 1;105(6):616-624.ABSTRACTStroke accounts for significant morbidity and mortality and is the fifth leading cause of death in the United States, with direct and indirect costs of more than $100 billion annually. Expedient recognition of acute neurologic deficits with appropriate history, physical examination, and glucose testing will help diagnose stroke and rule out mimicking presentations. The National Institutes of Health Stroke Scale should be used to determine stroke severity and to monitor for evolving changes in clinical presentation. Initial neuroimaging is used to differentiate between isc...
Source: American Family Physician - June 15, 2022 Category: Primary Care Authors: Edwin Y Choi Gilberto A Nieves Darrell Edward Jones Source Type: research

Increased plasma levels of circPTP4A2 and circTLK2 are associated with stroke injury
Ann Clin Transl Neurol. 2023 Jun 23. doi: 10.1002/acn3.51837. Online ahead of print.ABSTRACTOBJECTIVE: Accumulating studies have shown that circulating circular RNAs (circRNAs) represent novel biomarkers for many human diseases. We investigated whether plasma circPTP4A2 and circTLK2 levels are associated with stroke severity, infarct volume, stroke etiology, and functional outcome in acute ischemic stroke (AIS) patients.METHODS: We applied quantitative real-time PCR (qPCR) to measure plasma circPTP4A2 and circTLK2 levels of 236 AIS patients within 72 h of symptoms onset and 136 healthy controls. We further assessed the Nat...
Source: Atherosclerosis - June 23, 2023 Category: Cardiology Authors: Xingzhi Wang Shenyang Zhang Zuohui Zhang Jie Zu Hongjuan Shi Lu Yu Bingchen Lv Likun Cui Wenqi Mao Di Wu Guiyun Cui Source Type: research

Death and ADL Dependency After Scoring Zero on the NIHSS: A Swedish Retrospective Registry-Based Study
Discussion One of 17 patients has either died or become ADL-dependent 3 months after a 0-NIHSS stroke, stressing that these strokes are not always benign. Older and physically inactive patients are at greater risk of an adverse outcome.
Source: Neurology Clinical Practice - September 1, 2023 Category: Neurology Authors: Darehed, D., Reinholdsson, M., Viktorisson, A., Abzhandadze, T., Sunnerhagen, K. S. Tags: Outcome research, All Cerebrovascular disease/Stroke, Cohort studies Research Article Source Type: research

Prognostic Value of Plasma Neuroendocrine Biomarkers in Patients with Acute Ischaemic Stroke
Inflammation and activation of the neuroendocrine systems comprise important aspects of stroke pathophysiology. The present study investigated whether baseline plasma brain natriuretic peptide (BNP), N‐terminal pro‐brain natriuretic peptide (NT‐proBNP), cortisol and copeptin levels on admission can predict short‐term outcomes and mortality after acute ischaemic stroke. The study group consisted of 189 patients who had their first acute ischaemic stroke. Plasma levels of BNP, NT‐proBNP, cortisol and copeptin were evaluated to determine their value with respect to predicting functional outcome and mortality within ...
Source: Journal of Neuroendocrinology - August 20, 2013 Category: Endocrinology Authors: W.‐J. Tu, X. Dong, S.‐J. Zhao, D.‐G. Yang, H. Chen Tags: Original Article Source Type: research