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Infectious Disease: Adenoviruses
Vaccination: Covid Vaccine
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Total 388 results found since Jan 2013.
TWiV 1037: Antibodies, the good (CoV), the bad (Ad), the beautiful
TWiV reviews evidence that symptomatic adenovirus infection leads to thrombocytopenia, thrombosis, and production of anti-platelet factor 4 antibodies similar to the rare disorder seen after immunization with adenoviral vectored COVID-19 vaccines, and a monoclonal antibody isolated from a SARS survivor, following vaccination with a SARS-CoV-2 spike mRNA vaccine, that neutralizes a broad collection of ACE2-binding sarbecoviruses. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Link...
Source: This Week in Virology - MP3 Edition - August 20, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Intranasal inoculation of female BALB/c mice with replication-deficient human adenovirus type 5 expressing SARS-CoV-2 nucleocapsid protein aggravates lung pathology upon re-encountering the antigen
Virus Res. 2023 Aug 16:199201. doi: 10.1016/j.virusres.2023.199201. Online ahead of print.ABSTRACTPreclinical studies indicate that SARS-CoV-2 nucleocapsid (N)-based vaccines, along with other viral protein(s), confer protection in various animal models against infection by SARS-CoV-2 ancestral virus and variants of concern. However, the optimal vaccination procedure and the role of N-specific host adaptive immune responses remain elusive. Here, we report that intranasal inoculation with replication-deficient human adenovirus type 5 expressing SARS-CoV-2 N protein (Ad5-N) conferred no protection in the lung of female BALB/...
Source: Virus Research - August 18, 2023 Category: Virology Authors: Junxia Cao Hongjing Gu Xueting Zhang Hongfang Yun Jiarong Li Chuan-Yimu Si Jiyan Zhang Hui Wang Source Type: research
Herpes zoster reactivation after mRNA and adenovirus-vectored coronavirus disease 2019 vaccination: Analysis of National Health Insurance Database
CONCLUSIONS: mRNA COVID-19 vaccination possibly increases the risk of herpes zoster reactivation, and thus close follow-up for herpes zoster reactivation is required.PMID:37549237 | DOI:10.1093/infdis/jiad297
Source: Herpes - August 7, 2023 Category: Infectious Diseases Authors: Jin Gu Yoon Young-Eun Kim Min Joo Choi Won Suk Choi Yu Bin Seo Jaehun Jung Hak-Jun Hyun Hye Seong Eliel Nham Ji Yun Noh Joon Young Song Woo Joo Kim Dong Wook Kim Hee Jin Cheong Source Type: research
Viral vectors engineered for gene therapy
Int Rev Cell Mol Biol. 2023;379:1-41. doi: 10.1016/bs.ircmb.2023.05.005. Epub 2023 Jul 1.ABSTRACTGene therapy has seen major progress in recent years. Viral vectors have made a significant contribution through efficient engineering for improved delivery and safety. A large variety of indications such as cancer, cardiovascular, metabolic, hematological, neurological, muscular, ophthalmological, infectious diseases, and immunodeficiency have been targeted. Viral vectors based on adenoviruses, adeno-associated viruses, herpes simplex viruses, retroviruses including lentiviruses, alphaviruses, flaviviruses, measles viruses, rh...
Source: International Review of Cell and Molecular Biology - August 4, 2023 Category: Cytology Authors: Kenneth Lundstrom Source Type: research
