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Male circumcision and Sexually transmitted Infections & #8211; An update
Kajal S Mehta, Yogesh S Marfatia, Apexa P Jain, Dhiral J Shah, Disha S BaxiIndian Journal of Sexually Transmitted Diseases and AIDS 2021 42(1):1-6Role of male circumcision (MC) as a tool to prevent sexually transmitted infections (STIs)/human immunodeficiency virus (HIV) was assessed. An attempt was made to search articles related to association between MC and STIs/HIV. A thorough search was carried out to find out quality articles published in indexed specialty journals. Centers for Disease Control and Prevention and World Health Organization (WHO) sites were also referred. Warm and moist environment of area under foreski...
Source: Indian Journal of Sexually Transmitted Diseases - May 4, 2021 Category: Infectious Diseases Authors: Kajal S Mehta Yogesh S Marfatia Apexa P Jain Dhiral J Shah Disha S Baxi Source Type: research

HPV vaccination and the prevention of genital warts and precancerous lesions-current evidence and evaluation
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2021 Apr 13. doi: 10.1007/s00103-021-03316-x. Online ahead of print.ABSTRACTHuman papillomaviruses (HPVs) can cause both benign and malignant tumors. To date, more than 200 HPV types have been discovered, of which 12 are currently classified as high risk for cervical cancer. HPV types that affect the anogenital tract are sexually transmitted. Since 2006, prophylactic HPV vaccines have been available and should be administered before first sexual contact.HPVs infect epithelial cells and are worldwide the most common sexually transmitted viruses. Apart from cervi...
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - April 14, 2021 Category: International Medicine & Public Health Authors: Vanesa Osmani Stefanie J Klug Source Type: research

Declines in Prevalence of Human Papillomavirus Vaccine-Type Infection Among Females after Introduction of Vaccine - United States, 2003-2018
MMWR Morb Mortal Wkly Rep. 2021 Mar 26;70(12):415-420. doi: 10.15585/mmwr.mm7012a2.ABSTRACTHuman papillomavirus (HPV) is the most common sexually transmitted infection in the United States (1). Although most infections resolve without clinical sequalae, persistent HPV infection can cause cervical, other anogenital, and oropharyngeal cancers and anogenital warts. HPV vaccination has been recommended in the United States at age 11-12 years since 2006 for females and since 2011 for males. Catch-up vaccination is recommended through age 26 years.* A quadrivalent vaccine (4vHPV) targeting types 6, 11, 16, and 18 was mainly used...
Source: MMWR Morb Mortal Wkl... - March 25, 2021 Category: Epidemiology Authors: Hannah G Rosenblum Rayleen M Lewis Julia W Gargano Troy D Querec Elizabeth R Unger Lauri E Markowitz Source Type: research

Worldwide genetic variations in High-risk human papillomaviruses capsid L1 gene and their impact on vaccine efficiency
CONCLUSION: This study investigated the major capsid L1 genetic diversity of HPV16, 18, 31, 33, 58, 45, and 52 circulating in different populations around the world. Further investigations should be conducted to confirm their effect on immunogenicity and prophylactic vaccine efficiency.PMID:33636291 | DOI:10.1016/j.gene.2021.145533
Source: Gene - February 26, 2021 Category: Genetics & Stem Cells Authors: Loubna Oumeslakht Mouna Ababou Bouabid Badaoui Zineb Qmichou Source Type: research

Anti-viral therapy for the sexually transmitted viruses: recent updates on vaccine development.
Authors: Kardani K, Basimi P, Fekri M, Bolhassani A Abstract INTRODUCTION: The sexually transmitted infections (STIs) caused by viruses including human T cell leukemia virus type-1 (HTLV-1), human immunodeficiency virus-1 (HIV-1), human simplex virus-2 (HSV-2), hepatitis C virus (HCV), hepatitis B virus (HBV), and human papillomavirus (HPV) are major public health issues. These infections can cause cancer or result in long-term health problems. Due to high prevalence of STIs, a safe and effective vaccine is required to overcome these fatal viruses. AREAS COVERED: This review includes a comprehensive overview of...
Source: Expert Review of Clinical Pharmacology - August 27, 2020 Category: Drugs & Pharmacology Tags: Expert Rev Clin Pharmacol Source Type: research

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